(Q37276902)

English

Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses

scientific article published on 24 June 2009

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses (English)

1 reference

Europe PubMed Central

19 August 2017

author name string

Jacob T Minang

1

1 reference

Europe PubMed Central

19 August 2017

Matthew T Trivett

2

1 reference

Europe PubMed Central

19 August 2017

Lori V Coren

3

1 reference

Europe PubMed Central

19 August 2017

Eugene V Barsov

4

1 reference

Europe PubMed Central

19 August 2017

Michael Piatak

5

1 reference

Europe PubMed Central

19 August 2017

David E Ott

6

1 reference

Europe PubMed Central

19 August 2017

Claes Ohlen

7

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

24 June 2009

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

391

1 reference

Europe PubMed Central

19 August 2017

1

1 reference

Europe PubMed Central

19 August 2017

130-139

1 reference

Europe PubMed Central

19 August 2017

Toward an AIDS vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Selective downregulation of rhesus macaque and sooty mangabey major histocompatibility complex class I molecules by Nef alleles of simian immunodeficiency virus and human immunodeficiency virus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Not all cytokine-producing CD8+ T cells suppress simian immunodeficiency virus replication

1 reference

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Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

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6 September 2017

The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus

1 reference

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6 September 2017

Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

1 reference

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6 September 2017

nef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.

1 reference

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Differential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytes

1 reference

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6 September 2017

T-cell receptor:CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

The advantage of early recognition of HIV-infected cells by cytotoxic T-lymphocytes

1 reference

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6 September 2017

Viral persistence: HIV's strategies of immune system evasion

1 reference

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6 September 2017

How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Nonmyeloablative immunosuppressive regimen prolongs In vivo persistence of gene-modified autologous T cells in a nonhuman primate model

1 reference

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6 September 2017

Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

The explosive human immunodeficiency virus type 1 epidemic among injecting drug users of Kathmandu, Nepal, is caused by a subtype C virus of restricted genetic diversity

1 reference

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6 September 2017

The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Degradation of cell proteins and the generation of MHC class I-presented peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

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6 September 2017

HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism

1 reference

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6 September 2017

Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

1 reference

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6 September 2017

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

1 reference

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6 September 2017

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

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Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction

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Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes

1 reference

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Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor

1 reference

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Efficient inhibition of SIV replication in rhesus CD4+ T-cell clones by autologous immortalized SIV-specific CD8+ T-cell clones

1 reference

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Transduction with human telomerase reverse transcriptase immortalizes a rhesus macaque CD8+ T cell clone with maintenance of surface marker phenotype and function

1 reference

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Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques

1 reference

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Comprehensive analysis of nef functions selected in simian immunodeficiency virus-infected macaques

1 reference

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Impacts of Avidity and Specificity on the Antiviral Efficiency of HIV-1-Specific CTL

1 reference

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Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses

1 reference

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Nef interference with HIV-1-specific CTL antiviral activity is epitope specific

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Molecular and biological characterization of simian immunodeficiency virus macaque strain 32H proviral clones containing nef size variants.

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The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus

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The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells

1 reference

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HIV-1-specific CTLs effectively suppress replication of HIV-1 in HIV-1-infected macrophages.

1 reference

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HIV evolution: CTL escape mutation and reversion after transmission

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CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

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Emergence of CTL coincides with clearance of virus during primary simian immunodeficiency virus infection in rhesus monkeys

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HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

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Dynamics of T cell responses in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2009.06.008

7 January 2021

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2009.06.008

7 January 2021

HIV- I Nef severely impairs thymocyte development and peripheral T-cell function by a CD4-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2009.06.008

7 January 2021

Cutting Edge: Epitope-dependent effect of Nef-mediated HLA class I down-regulation on ability of HIV-1-specific CTLs to suppress HIV-1 replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2009.06.008

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CTL-Mediated Selective Pressure Influences Dynamic Evolution and Pathogenic Functions of HIV-1 Nef

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Cytotoxic T lymphocyte activity in children infected with HIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/19555986

12 December 2020

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10.1016/J.VIROL.2009.06.008

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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