(Q37279691)

19 August 2017

Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents (English)

1 reference

19 August 2017

Lee Roy Morgan

1

1 reference

19 August 2017

Robert F Struck

2

1 reference

19 August 2017

William R Waud

3

1 reference

19 August 2017

Blaise LeBlanc

4

1 reference

19 August 2017

Andrew H Rodgers

5

1 reference

19 August 2017

Branko S Jursic

6

1 reference

19 August 2017

3 March 2009

1 reference

Cancer Chemotherapy and Pharmacology

19 August 2017

1 reference

19 August 2017

64

1 reference

19 August 2017

4

1 reference

19 August 2017

829-835

1 reference

https://scigraph.springernature.com/pub.10.1007/s00280-009-0933-9

19 August 2017

0 references

cites work

Dose-limiting neurotoxicity in a phase I study of penclomedine (NSC 388720, CRC 88-04), a synthetic alpha-picoline derivative, administered intravenously

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolites of penclomedine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Tissue and tumor distribution of C-penclomedine in rats.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

4-Demethylpenclomedine, an antitumor-active, potentially nonneurotoxic metabolite of penclomedine.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Preclinical antitumor activity of an alpha-picoline derivative, penclomedine (NSC 338720), on human and murine tumors.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Preclinical antitumor activity of penclomedine in mice: cross-resistance, schedule dependence, and oral activity against tumor xenografts in brain.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Murine pharmacokinetics and metabolism of penclomedine [3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine, NSC 338720]

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Polar, functionalized guanine-O6 derivatives resistant to repair by O6-alkylguanine-DNA alkyltransferase: implications for the design of DNA-modifying drugs.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Thiolo-, thiono- and dithiocarbonate and thiocarbamate derivatives of demethylpenclomedine as novel anticancer agents

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

The alkylating agent penclomedine induces degeneration of purkinje cells in the rat cerebellum

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717391

Phase I and pharmacologic study of penclomedine, a novel alkylating agent, in patients with solid tumors

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19255760

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase I clinical and pharmacokinetic trial of penclomedine using a novel, two-stage trial design for patients with advanced malignancy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19255760

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Murine and human in vivo penclomedine metabolism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19255760

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00280-009-0933-9

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

19255760

1 reference