(Q37279814)

English

Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort

scientific article published on 20 May 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

0 references

drotrecogin alfa

1 reference

based on heuristic

inferred from title

author name string

Richard V Hodder

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Richard Hall

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

James A Russell

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Harold N Fisher

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Bobbie Lee

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

20 May 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

R78

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Recombinant human activated protein C: current insights into its mechanism of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Evaluating the use of Drotrecogin alfa (activated) in adult severe sepsis: a Canadian multicenter observational study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Clinical manifestations of disordered microcirculatory perfusion in severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Clinical review: Drotrecogin alfa (activated) as adjunctive therapy for severe sepsis--practical aspects at the bedside and patient identification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

The epidemiology of sepsis in the United States from 1979 through 2000

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Early goal-directed therapy in the treatment of severe sepsis and septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Epidemiology of sepsis: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

6 September 2017

Guidance on patient identification and administration of recombinant human activated protein C for the treatment of severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

14 September 2017

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

3 September 2018

Early changes in organ function predict eventual survival in severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

3 September 2018

A blueprint for a sepsis protocol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

3 September 2018

Predictors of hospital mortality for patients with severe sepsis treated with Drotrecogin alfa (activated).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

3 September 2018

Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

3 September 2018

Systemic Inflammatory Response and Progression to Severe Sepsis in Critically Ill Infected Patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717441

3 December 2018

Determinants of mortality in patients with severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19457240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/19457240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment*

1 reference

https://pubmed.ncbi.nlm.nih.gov/19457240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of Systemic Inflammatory Response Syndrome and Sepsis on Outcome of Critically Ill Infected Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19457240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/19457240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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