Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37282237)
Watch
English
Long-range coupling in an allosteric receptor revealed by mutant cycle analysis
scientific article published on April 2009
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
title
Long-range coupling in an allosteric receptor revealed by mutant cycle analysis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author
Jai A P Shanata
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
Henry Lester
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author name string
Kristin R Gleitsman
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
Shawnalea J Frazier
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
Dennis A Dougherty
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
language of work or name
English
0 references
publication date
1 April 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
published in
Biophysical Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
volume
96
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
page(s)
3168-3178
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
cites work
A conserved salt bridge critical for GABA(A) receptor function and loop C dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Cys-loop neuroreceptors: structure to the rescue?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Unnatural amino acid mutagenesis of the GABA(A) receptor binding site residues reveals a novel cation-pi interaction between GABA and beta 2Tyr97
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Recent advances in Cys-loop receptor structure and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Dynamics of the acetylcholine receptor pore at the gating transition state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Allosteric mechanisms of signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Cys-loop receptors: new twists and turns
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
How fast does the GluR1Qflip channel open?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Structure and gating mechanism of the acetylcholine receptor pore
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Coupling of agonist binding to channel gating in the GABA(A) receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Aromatics at the murine nicotinic receptor agonist binding site: mutational analysis of the alphaY93 and alphaW149 residues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
The glycinergic inhibitory synapse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Nicotinic receptors at the amino acid level
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
The 5-HT3B subunit is a major determinant of serotonin-receptor function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Single binding versus single channel recordings: a new approach to study ionotropic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9' position
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: mutations of alpha-subunit tyrosine 190 affect both binding and gating
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Acetylcholine binding by a synthetic receptor: implications for biological recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
6 September 2017
Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
14 September 2017
Contributions of the non-alpha subunit residues (loop D) to agonist binding and channel gating in the muscle nicotinic acetylcholine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
14 September 2017
A mutational analysis of the acetylcholine receptor channel transmitter binding site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
14 September 2017
Acetylcholine receptor gating is influenced by the polarity of amino acids at position 9' in the M2 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
28 September 2017
Binding sites contribute unequally to the gating of mouse nicotinic alpha D200N acetylcholine receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
28 September 2017
In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
26 June 2018
Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
26 June 2018
Mutational analysis of ligand-induced activation of the Torpedo acetylcholine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
26 June 2018
An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Ligand-binding residues integrate affinity and efficacy in the NMDA receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Contributions of Torpedo nicotinic acetylcholine receptor gamma Trp-55 and delta Trp-57 to agonist and competitive antagonist function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Channel opening locks agonist onto the GABAC receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718292
retrieved
3 September 2018
Nicotinic receptors in wonderland
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19383461
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19383461
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BPJ.2008.12.3949
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PMC publication ID
2718292
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PubMed publication ID
19383461
1 reference
stated in
Europe PubMed Central
PMC publication ID
2718292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19383461%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
ResearchGate publication ID
24345627
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit