(Q37284465)

English

Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene

scientific article published on 26 March 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

phosphorylation

0 references

author name string

Sebnem Unlu

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Arvind Kumar

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Wayne R Waterman

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Junichi Tsukada

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kent Z Q Wang

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Deborah L Galson

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Philip E Auron

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

26 March 2007

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Molecular Immunology

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

44

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

3364-3379

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Structural bases of unphosphorylated STAT1 association and receptor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

STATs dimerize in the absence of phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Stats: transcriptional control and biological impact

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Mechanisms of Type I interferon cell signaling and STAT-mediated transcriptional responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

ICSBP/IRF-8 transactivation: a tale of protein-protein interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Identification of LIL-STAT in monocytic leukemia cells and monocytes after stimulation with interleukin-6 or interferon gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

SHP1 protein-tyrosine phosphatase inhibits gp91PHOX and p67PHOX expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous Cis elements in the CYBB and NCF2 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Biologic consequences of Stat1-independent IFN signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Adenovirus E1A down-regulates LMP2 transcription by interfering with the binding of stat1 to IRF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Differential expression and distinct functions of IFN regulatory factor 4 and IFN consensus sequence binding protein in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Gamma interferon augments macrophage activation by lipopolysaccharide by two distinct mechanisms, at the signal transduction level and via an autocrine mechanism involving tumor necrosis factor alpha and interleukin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

How cells respond to interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Differential binding activity of the transcription factor LIL-STAT in immature and differentiated normal and leukemic myeloid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Three-dimensional structure of the Stat3beta homodimer bound to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

A novel STAT-like factor mediates lipopolysaccharide, interleukin 1 (IL-1), and IL-6 signaling and recognizes a gamma interferon activation site-like element in the IL1B gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

A CRE/ATF-like site in the upstream regulatory sequence of the human interleukin 1 beta gene is necessary for induction in U937 and THP-1 monocytic cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

An interferon-gamma activation sequence mediates the transcriptional regulation of the IgG Fc receptor type IC gene by interferon-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Detection of two tissue-specific DNA-binding proteins with affinity for sites in the mouse beta-globin intervening sequence 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

6 September 2017

Interleukin 1 Activates STAT3/Nuclear Factor-κB Cross-talk via a Unique TRAF6- and p65-dependent Mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

14 September 2017

Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

14 September 2017

Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

14 September 2017

PU.1 and multiple IFN regulatory factor proteins synergize to mediate transcriptional activation of the human IL-1 beta gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

28 September 2017

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

28 September 2017

Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

28 September 2017

Cyclic AMP signaling pathways are important in IL-1 beta transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

28 September 2017

Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

26 June 2018

A two-step mechanism for recruitment of Pip by PU.1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

26 June 2018

Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

26 June 2018

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

26 June 2018

Interleukin-6 can prime THP-1 macrophages for enhanced production of tumor necrosis factor-α in response to LPS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

26 June 2018

Conserved ETS domain arginines mediate DNA binding, nuclear localization, and a novel mode of bZIP interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

3 September 2018

Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

3 September 2018

NF-IL6 (C/EBPbeta ) vigorously activates il1b gene expression via a Spi-1 (PU.1) protein-protein tether.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719065

3 September 2018

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of interleukin-1 beta gene expression in activated RAW 264.7 macrophages by interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plasticity of dendritic cell responses to pathogens and their components

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interleukin-1beta gene is transcribed from a poised promoter architecture in monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of PU.1/IRF-4/DNA ternary complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the human prointerleukin 1 beta gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17386941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLIMM.2007.02.016

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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