Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37285576)
Watch
English
Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection
scholarly article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
title
Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection
(English)
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
main subject
Reovirus
1 reference
based on heuristic
inferred from title
author name string
Kara L Norman
series ordinal
1
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
Kensuke Hirasawa
series ordinal
2
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
An-Dao Yang
series ordinal
3
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
Michael A Shields
series ordinal
4
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
Patrick W K Lee
series ordinal
5
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
language of work or name
English
0 references
publication date
19 July 2004
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
volume
101
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
page(s)
11099-11104
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
issue
30
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
cites work
Ral-GTPases: approaching their 15 minutes of fame
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Distinct requirements for Ras oncogenesis in human versus mouse cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Ras-dependent regulation of c-Jun phosphorylation is mediated by the Ral guanine nucleotide exchange factor-Ral pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Reovirus therapy of tumors with activated Ras pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Signaling pathways in Ras-mediated tumorigenicity and metastasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Stimulation of gene induction and cell growth by the Ras effector Rlf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Evidence that the epidermal growth factor receptor on host cells confers reovirus infection efficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Multiple Ras functions can contribute to mammalian cell transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
The preferential cytotoxicity of reovirus for certain transformed cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Differential sensitivity of normal and transformed human cells to reovirus infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
6 September 2017
Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
14 September 2017
Addition of exogenous protease facilitates reovirus infection in many restrictive cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
14 September 2017
Oncolytic viral therapy for human pancreatic cancer cells by reovirus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
14 September 2017
The v-erbB oncogene confers enhanced cellular susceptibility to reovirus infection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
14 September 2017
Selective p38 activation in human non-small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
28 September 2017
Oncolytic reovirus against ovarian and colon cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
28 September 2017
Insulin stimulation of gene expression mediated by p21ras activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
28 September 2017
Mitogen-activated protein kinase cascades as regulators of stress responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
26 June 2018
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
26 June 2018
A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
26 June 2018
Endogenous inhibitors of the dsRNA-dependent eIF-2 alpha protein kinase PKR in normal and ras-transformed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
26 June 2018
Oncogenic ras induces an inhibitor of double-stranded RNA-dependent eukaryotic initiation factor 2 alpha-kinase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
26 June 2018
Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Selective reovirus killing of bladder cancer in a co-culture spheroid model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Reovirus oncolysis as a novel purging strategy for autologous stem cell transplantation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Reovirus therapy of lymphoid malignancies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Reovirus oncolysis of human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Reovirus as an oncolytic agent against experimental human malignant gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Increasing complexity of Ras signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=503746
retrieved
3 September 2018
Polypeptide components of virions, top component and cores of reovirus type 3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15263068
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15263068
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0404310101
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
ADS bibcode
2004PNAS..10111099N
0 references
PMCID
503746
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
PubMed ID
15263068
1 reference
stated in
Q5412157
PMCID
503746
retrieved
19 August 2017
ResearchGate publication ID
8446641
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
