(Q37287418)

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The association between the T309G polymorphism of the MDM2 gene and sensitivity to anticancer drug is dependent on the p53 mutational status in cellular models.

scientific article published on 09 June 2009

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19513075%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

The association between the T309G polymorphism of the MDM2 gene and sensitivity to anticancer drug is dependent on the p53 mutational status in cellular models (English)

1 reference

Europe PubMed Central

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30 January 2020

5

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30 January 2020

7

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30 January 2020

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N Faur

1

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30 January 2020

L Araud

2

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30 January 2020

A Laroche-Clary

3

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30 January 2020

J Kanno

4

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30 January 2020

T Yamori

6

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30 January 2020

V Le Morvan

8

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30 January 2020

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9 June 2009

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30 January 2020

British Journal of Cancer

1 reference

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30 January 2020

101

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30 January 2020

2

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30 January 2020

350-356

1 reference

Europe PubMed Central

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30 January 2020

MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia

1 reference

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Genetic variants contributing to daunorubicin-induced cytotoxicity

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6 September 2017

Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach

1 reference

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6 September 2017

A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.

1 reference

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6 September 2017

Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen

1 reference

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6 September 2017

A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans

1 reference

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6 September 2017

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

1 reference

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6 September 2017

Identification of gene polymorphisms of human DNA topoisomerase I in the National Cancer Institute panel of human tumour cell lines.

1 reference

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6 September 2017

Relationships between genetic polymorphisms and anticancer drug cytotoxicity vis-à-vis the NCI-60 panel

1 reference

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6 September 2017

"Per cell" normalization method for mRNA measurement by quantitative PCR and microarrays

1 reference

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6 September 2017

p53 family members and chemoresistance in cancer: what we know and what we need to know

1 reference

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6 September 2017

Surfing the p53 network

1 reference

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6 September 2017

A gene expression database for the molecular pharmacology of cancer

1 reference

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6 September 2017

Apoptosis, p53, and tumor cell sensitivity to anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

6 September 2017

A simple p53 functional assay for screening cell lines, blood, and tumors

1 reference

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6 September 2017

Meta-analysis of the role of p53 status in isogenic systems tested for sensitivity to cytotoxic antineoplastic drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

14 September 2017

Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

14 September 2017

Involvement of gene polymorphisms of thymidylate synthase in gene expression, protein activity and anticancer drug cytotoxicity using the NCI-60 panel

1 reference

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14 September 2017

DNA repair gene polymorphisms affect cytotoxicity in the National Cancer Institute Human Tumour Cell Line Screening Panel

1 reference

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14 September 2017

Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

14 September 2017

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

14 September 2017

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

14 September 2017

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

14 September 2017

DNA damage, oncogenesis and the p53 tumour-suppressor gene

1 reference

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14 September 2017

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

1 reference

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26 June 2018

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

1 reference

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26 June 2018

p53 polymorphic variants at codon 72 and the outcome of therapy in randomized breast cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720206

3 September 2018

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

1 reference

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3 September 2018

Enhancing TRAIL-induced apoptosis by Bcl-X(L) siRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605096

21 January 2018

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19513075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 can provoke apoptosis in p53-deficient Hep3B cells with delayed kinetics relative to wild-type p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/19513075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19513075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scarff-Bloom-Richardson (SBR) grading: a pleiotropic marker of chemosensitivity in invasive ductal breast carcinomas treated by neoadjuvant chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19513075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJC.6605096

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19513075%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19513075%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19513075%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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