(Q37299856)

19 August 2017

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title

The long road to the thymus: the generation, mobilization, and circulation of T-cell progenitors in mouse and man. (English)

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19 August 2017

Daniel A Zlotoff

1

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PubMed ID

18925398

19 August 2017

Benjamin A Schwarz

series ordinal

2

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PubMed ID

18925398

19 August 2017

Avinash Bhandoola

series ordinal

3

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19 August 2017

17 October 2008

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Seminars in Immunopathology

19 August 2017

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19 August 2017

30

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19 August 2017

371-382

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19 August 2017

4

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https://scigraph.springernature.com/pub.10.1007/s00281-008-0133-4

19 August 2017

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The blood contains multiple distinct progenitor populations with clonogenic B and T lineage potential

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12 December 2020

Purification and characterization of mouse hematopoietic stem cells

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12 December 2020

Physiological migration of hematopoietic stem and progenitor cells.

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12 December 2020

Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages

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12 December 2020

A multistep adhesion cascade for lymphoid progenitor cell homing to the thymus

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12 December 2020

Signaling pathways governing stem-cell fate

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12 December 2020

Soluble c-kit receptor mobilizes hematopoietic stem cells to peripheral blood in mice.

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12 December 2020

The role of CCL21 in recruitment of T-precursor cells to fetal thymi

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12 December 2020

Circulating autologous stem cells collected in very early remission from acute non-lymphoblastic leukaemia produce prompt but incomplete haemopoietic reconstitution after high dose melphalan or supralethal chemoradiotherapy

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12 December 2020

Differentiation of hematopoietic stem cells in irradiated mouse thymic lobes. Kinetics and phenotype of progeny

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12 December 2020

Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.

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12 December 2020

Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential.

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12 December 2020

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

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12 December 2020

Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

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12 December 2020

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

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12 December 2020

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment

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12 December 2020

The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts

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12 December 2020

Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system

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12 December 2020

A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

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12 December 2020

Evidence for stem cells in the peripheral blood of mice

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12 December 2020

Uncertainty in the niches that maintain haematopoietic stem cells

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12 December 2020

Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization

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12 December 2020

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

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12 December 2020

Identification of a novel, human multilymphoid progenitor in cord blood

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12 December 2020

Identification of a T lineage-committed progenitor in adult blood.

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12 December 2020

Emergence of T cell progenitors without B cell or myeloid differentiation potential at the earliest stage of hematopoiesis in the murine fetal liver.

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12 December 2020

Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor

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Peripheral blood stem cells for allogeneic transplantation: a review

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12 December 2020

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

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12 December 2020

Hematopoietic thymocyte precursors. I. Assay and kinetics of the appearance of progeny

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12 December 2020

Notch signaling controls the generation and differentiation of early T lineage progenitors

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12 December 2020

Lymphocyte depletion during treatment with intensive chemotherapy for cancer

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12 December 2020

Increase in circulating stem cells following chemotherapy in man

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12 December 2020

Expression of interleukin-7 receptor by lineage-negative human bone marrow progenitors with enhanced lymphoid proliferative potential and B-lineage differentiation capacity.

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12 December 2020

Prospective isolation of human clonogenic common myeloid progenitors

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12 December 2020

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

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12 December 2020

Human immunodeficiency virus-1 infection interrupts thymopoiesis and multilineage hematopoiesis in vivo

1 reference

12 December 2020

Dynamics of Thymus-Colonizing Cells during Human Development

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12 December 2020

Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation.

1 reference

12 December 2020

Successful autologous transplantation with peripheral blood hemopoietic cells in a patient with acute leukemia

1 reference

12 December 2020

A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision

1 reference

12 December 2020

Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver.

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12 December 2020

Hematopoietic stem cells and their niche.

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12 December 2020

The relationship between the spleen colony-forming cell and the haemopoietic stem cell

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12 December 2020

BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

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12 December 2020

Osteoblastic cells regulate the haematopoietic stem cell niche

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12 December 2020

Hematopoietic stem cells are uniquely selective in their migratory response to chemokines

1 reference

12 December 2020

Requirement for Notch1 signals at sequential early stages of intrathymic T cell development

1 reference

12 December 2020

The earliest thymic progenitors for T cells possess myeloid lineage potential.

1 reference

12 December 2020

Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

1 reference

12 December 2020

Anti-VLA4/VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway

1 reference

12 December 2020

Hematopoietic stem/progenitor cell mobilization. A continuing quest for etiologic mechanisms

1 reference

12 December 2020

Hematopoietic stem cells: generation and self-renewal.

1 reference

12 December 2020

Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation

1 reference

12 December 2020

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

1 reference

12 December 2020

The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors

1 reference

12 December 2020

Circulating hematopoietic progenitors with T lineage potential

1 reference

12 December 2020

Major T cell progenitor activity in bone marrow-derived spleen colonies

1 reference

12 December 2020

Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus

1 reference

12 December 2020

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

1 reference

12 December 2020

T cell development and receptor diversity during aging

1 reference

12 December 2020

Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo

1 reference

12 December 2020

Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway

1 reference

12 December 2020

The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice

1 reference

12 December 2020

Identification of the haematopoietic stem cell niche and control of the niche size

1 reference

12 December 2020

Adult T-cell progenitors retain myeloid potential

1 reference

12 December 2020

Selective thymus settling regulated by cytokine and chemokine receptors

1 reference

12 December 2020

Murine hematopoietic stem and progenitor cells: I. Enrichment and biologic characterization

1 reference

12 December 2020

Trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis

1 reference

12 December 2020

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

1 reference

12 December 2020

Lentivector-mediated clonal tracking reveals intrinsic heterogeneity in the human hematopoietic stem cell compartment and culture-induced stem cell impairment

1 reference

12 December 2020

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

1 reference

12 December 2020

The biology and clinical uses of blood stem cells.

1 reference

12 December 2020

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

1 reference

12 December 2020

Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment.

1 reference

12 December 2020

Isolation of a candidate human hematopoietic stem-cell population

1 reference

12 December 2020

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

1 reference

12 December 2020

Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization

1 reference

12 December 2020

Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. A study in parabiotic mice

1 reference

12 December 2020

A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitution

1 reference

12 December 2020

Current concepts of the immunological function of the thymus

1 reference

12 December 2020

Homing and cellular traffic in lymph nodes

1 reference

12 December 2020

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

1 reference

12 December 2020

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

1 reference

12 December 2020

Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function

1 reference

12 December 2020

Cytokines and hematopoietic stem cell mobilization

1 reference

12 December 2020

Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche.

1 reference

12 December 2020

Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF

1 reference

12 December 2020

Haematopoietic stem cell release is regulated by circadian oscillations

1 reference

12 December 2020

On the sparse seeding of bone marrow and thymus in radiation chimaeras

1 reference

12 December 2020

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome

1 reference

12 December 2020

Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny

1 reference

12 December 2020

A short primer on early molecular and cellular events in thymus organogenesis and replacement

1 reference

12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

1 reference

12 December 2020

Distinct classes of human stem cells that differ in proliferative and self-renewal potential

1 reference

12 December 2020

Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity

1 reference

12 December 2020

Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.

1 reference

12 December 2020

The relative spatial distributions of CFUs and CFUc in the normal mouse femur

1 reference

12 December 2020

Thymic microenvironments for T cell differentiation and selection.

1 reference

12 December 2020

Lineage specification and plasticity in CD19- early B cell precursors

1 reference

12 December 2020

Hemopoietic Stem Cells in Human Peripheral Blood

1 reference

12 December 2020

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

1 reference

12 December 2020

Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy

1 reference

12 December 2020

Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells

1 reference

12 December 2020

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

1 reference

12 December 2020

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

12 December 2020

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

1 reference

12 December 2020

Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells

1 reference

12 December 2020

Characterization of peripheral blood stem cells in mice

1 reference

12 December 2020

Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood

1 reference

12 December 2020

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors

1 reference

12 December 2020

A human postnatal lymphoid progenitor capable of circulating and seeding the thymus

1 reference

12 December 2020

Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors

1 reference

12 December 2020

Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1

1 reference

12 December 2020

Identification of a bone marrow precursor of the earliest thymocytes in adult mouse

1 reference

12 December 2020

Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor.

1 reference

12 December 2020

Stem cell factor is a potent synergistic factor in hematopoiesis

1 reference

12 December 2020

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

1 reference

12 December 2020

Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

1 reference

12 December 2020

Donor-derived hematopoietic stem cells in organ transplantation: technical aspects and hurdles yet to be cleared

1 reference

12 December 2020

Strategies to enhance T-cell reconstitution in immunocompromised patients

1 reference

12 December 2020

Turnover of circulating hematopoietic stem cells

1 reference

12 December 2020

Little evidence for developmental plasticity of adult hematopoietic stem cells.

1 reference

12 December 2020

Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.

1 reference

12 December 2020

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

12 December 2020

Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin-CD34+CD38- population.

1 reference

12 December 2020

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

1 reference

12 December 2020

The Biology of Hematopoietic Stem Cells

1 reference

12 December 2020

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood

1 reference

12 December 2020

Autologous transplantation of blood-derived hemopoietic stem cells after myeloablative therapy in a patient with Burkitt's lymphoma

1 reference

12 December 2020

The B lineage potential of thymus settling progenitors is critically dependent on mouse age.

1 reference

12 December 2020

Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization.

1 reference

12 December 2020

Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance.

1 reference

12 December 2020

10.1007/S00281-008-0133-4

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18925398