(Q37311508)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Genetic and vascular modifiers of age-sensitive cognitive skills: effects of COMT, BDNF, ApoE, and hypertension (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

main subject

arterial hypertension

0 references

author

Karen M. Rodrigue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Naftali Raz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Kristen M Kennedy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Susan Land

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

publication date

1 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

105-116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

Human aging magnifies genetic effects on executive functioning and working memory

21 January 2020

cites work

1 reference

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6 September 2017

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Impact of the COMT Val108/158 Met and DAT genotypes on prefrontal function in healthy subjects.

6 September 2017

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Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function

6 September 2017

1 reference

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6 September 2017

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Cholesterol and triglycerides moderate the effect of apolipoprotein E on memory functioning in older adults

6 September 2017

1 reference

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DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability.

6 September 2017

1 reference

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The influence of APOE status on episodic and semantic memory: data from a population-based study

6 September 2017

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Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers

6 September 2017

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6 September 2017

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COMT genotype, gender and cognition in community-dwelling, older adults

6 September 2017

1 reference

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Synaptic plasticity in early aging

6 September 2017

1 reference

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Differential aging of the brain: patterns, cognitive correlates and modifiers

6 September 2017

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The correlative triad among aging, dopamine, and cognition: current status and future prospects

6 September 2017

1 reference

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The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks

6 September 2017

1 reference

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Variant BDNF (Val66Met) impact on brain structure and function

6 September 2017

1 reference

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Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers

6 September 2017

1 reference

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Mesocortical dopamine modulation of executive functions: beyond working memory

6 September 2017

1 reference

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Investigating cognitive genetics and its implications for the treatment of cognitive deficit

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

APOE polymorphism, socioeconomic status and cognitive function in mid-life--the Whitehall II longitudinal study.

6 September 2017

1 reference

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Differential dopaminergic modulation of executive control in healthy subjects

6 September 2017

1 reference

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Apolipoprotein E and category fluency: evidence for reduced semantic access in healthy normal controls at risk for developing Alzheimer's disease

6 September 2017

1 reference

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Brain-derived neurotrophic factor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

6 September 2017

1 reference

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The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

6 September 2017

1 reference

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The apolipoprotein E epsilon 2 allele and decline in episodic memory

6 September 2017

1 reference

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Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

6 September 2017

1 reference

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Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

6 September 2017

1 reference

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Adult age differences in memory performance: tests of an associative deficit hypothesis

6 September 2017

1 reference

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Calcium regulation of the brain-derived neurotrophic factor gene

6 September 2017

1 reference

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Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond

6 September 2017

1 reference

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Gender differences in episodic memory

6 September 2017

1 reference

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Substantial genetic influence on cognitive abilities in twins 80 or more years old.

6 September 2017

1 reference

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The processing-speed theory of adult age differences in cognition

6 September 2017

1 reference

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

6 September 2017

1 reference

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Facts and fiction about memory aging: a quantitative integration of research findings

6 September 2017

1 reference

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The assessment and analysis of handedness: The Edinburgh inventory

6 September 2017

1 reference

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6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Acute and long-term associations between ApoE genetic polymorphism, cortisol levels, and declarative memory performance in older adults

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Distribution of catechol-O-methyltransferase expression in human central nervous system.

26 June 2018

1 reference

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Impaired autoregulation in an experimental model of chronic cerebral hypoperfusion in rats

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Aging, inhibition, working memory, and speed

26 June 2018

1 reference

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Age differences in primary mental ability factors.

26 June 2018

1 reference

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COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

BDNF Val66Met polymorphism significantly affects d' in verbal recognition memory at short and long delays.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Association between apolipoprotein E4 and cognitive decline in elderly adults

2 September 2018

1 reference

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Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly.

2 September 2018

1 reference

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Apolipoprotein E epsilon4 genotype and gender: effects on memory.

2 September 2018

1 reference

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Genetics of verbal working memory processes: a twin study of middle-aged men.

2 September 2018

1 reference

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Apomorphine effects on episodic memory in young healthy volunteers.

2 September 2018

1 reference

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Apolipoprotein E affects both myelin breakdown and cognition: implications for age-related trajectories of decline into dementia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Differential course of executive control changes during normal aging.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Effects of sex and APOE epsilon4 on object recognition and spatial navigation in the elderly.

2 September 2018

1 reference

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The contribution of apolipoprotein E alleles on cognitive performance and dynamic neural activity over six decades.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Acute serotonin and dopamine depletion improves attentional control: findings from the stroop task.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Longitudinal genetic analysis of executive function in elderly men.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Hypertension downregulates the expression of brain-derived neurotrophic factor in the ischemia-vulnerable hippocampal CA1 and cortical areas after carotid artery occlusion.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Predicting memory decline in normal elderly: genetics, MRI, and cognitive reserve.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Interactive effects of APOE and CHRNA4 on attention and white matter volume in healthy middle-aged and older adults.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Effect of the BDNF V166M polymorphism on working memory in healthy adolescents.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

The brain-derived neurotrophic factor Val66Met polymorphism is associated with age-related change in reasoning skills.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Influence and interactions of cathepsin D, HLA-DRB1 and APOE on cognitive abilities in an older non-demented population.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Scaling of visuospatial attention undergoes differential longitudinal change as a function of APOE genotype prior to old age: results from the NIMH BIOCARD study.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Deficits in inhibition and flexibility are associated with the APOE-E4 allele in nondemented older adults.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

The longitudinal relationship between processing speed and cognitive ability: genetic and environmental influences.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Effect of COMT Val158Met polymorphism on the Continuous Performance Test, Identical Pairs Version: tuning rather than improving performance

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Catechol O-methyltransferase Val158Met polymorphism is associated with cognitive performance in nondemented adults

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

The influence of the dopaminergic system on cognitive functioning: A molecular genetic approach

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

The functional COMT polymorphism, Val 158 Met, is associated with logical memory and the personality trait intellect/imagination in a cohort of healthy 79 year olds

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Association between BDNF val66 met genotype and episodic memory.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Apolipoprotein E epsilon4 allele and lorazepam effects on memory in high-functioning older adults

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Apolipoprotein E and cognitive performance: a meta-analysis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Meta-analysis of genetic association studies.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Apolipoprotein e gene variability and cognitive functions at age 79: a follow-up of the Scottish mental survey of 1932.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Longitudinal changes in cognition and behavior in asymptomatic carriers of the APOE e4 allele.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Utilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Hypertension and the brain: vulnerability of the prefrontal regions and executive functions.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Regulation of Blood Pressure by Dopamine Receptors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Apolipoprotein E epsilon 4 affects new learning in cognitively normal individuals at risk for Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

The role of APOE-epsilon4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Working memory and apolipoprotein E: what's the connection?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Genetic structure of spatial and verbal working memory.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Patterns of cognitive ageing.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Elucidating the contributions of processing speed, executive ability, and frontal lobe volume to normal age-related differences in fluid intelligence.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Neuroanatomical correlates of cognitive aging: evidence from structural magnetic resonance imaging.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

NIDDM and blood pressure as risk factors for poor cognitive performance. The Framingham Study

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Hypertension and neuropsychological performance in men: interactive effects of age.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

High Systolic Blood Pressure Is Associated With Val/Val Genotype in the Catechol-O-Methyltransferase GeneThe Nord-Trøndelag Health Study (HUNT)

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729285

APOE genotype and cognitive decline in a middle-aged cohort

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19210038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

COMT genotype and cognitive ability: a longitudinal aging study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19210038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

COMT val158Met and executive control: a test of the benefit of specific deficits to translational research

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19210038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1037/A0013487

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19210038%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference