(Q37320501)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

2 references

8 February 2021

Imaging of EGFR and EGFR tyrosine kinase overexpression in tumors by nuclear medicine modalities (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

2 October 2019

1 reference

15 December 2019

1 reference

inferred from abstract

1 reference

8 February 2021

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Eyal Mishani

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Galith Abourbeh

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Martin Eiblmaier

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

1 reference

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

Current Pharmaceutical Design

26 December 2019

published in

7 references

3 April 2019

31 July 2019

28 September 2019

2 October 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

8 February 2021

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

issue

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

2983-2998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.5 Generic

26 December 2019

copyright license

6 references

3 April 2019

31 July 2019

28 September 2019

2 October 2019

15 December 2019

on focus list of Wikimedia project

8 February 2021

ScienceSource

0 references

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Panitumumab: in the treatment of metastatic colorectal cancer

6 September 2017

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Comparing antibody and small-molecule therapies for cancer

6 September 2017

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Selecting lung cancer patients for treatment with epidermal growth factor receptor tyrosine kinase inhibitors by immunohistochemistry and fluorescence in situ hybridization--why, when, and how?

6 September 2017

1 reference

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Tyrphostins and other tyrosine kinase inhibitors

6 September 2017

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Combining targeted therapies and drugs with multiple targets in the treatment of NSCLC.

6 September 2017

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High-affinity epidermal growth factor receptor (EGFR) irreversible inhibitors with diminished chemical reactivities as positron emission tomography (PET)-imaging agent candidates of EGFR overexpressing tumors

6 September 2017

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Erlotinib in lung cancer - molecular and clinical predictors of outcome

6 September 2017

1 reference

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Radiolabeled peptides in oncology: role in diagnosis and treatment

6 September 2017

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State-of-the art therapy for gastrointestinal stromal tumors

6 September 2017

1 reference

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Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

6 September 2017

1 reference

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

6 September 2017

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Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

6 September 2017

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

6 September 2017

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

6 September 2017

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Tyrosine kinase receptors as attractive targets of cancer therapy

6 September 2017

1 reference

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A census of human cancer genes

6 September 2017

1 reference

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The HER receptor family: a rich target for therapeutic development

6 September 2017

1 reference

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Epidermal growth factor receptor: a promising target in solid tumours

6 September 2017

1 reference

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Targeting angiogenesis: a review of angiogenesis inhibitors in the treatment of lung cancer

6 September 2017

1 reference

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EGF receptor as a therapeutic target

6 September 2017

1 reference

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6 September 2017

1 reference

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Protein kinase inhibitors as a therapeutic modality

6 September 2017

1 reference

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The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors

6 September 2017

1 reference

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The epidermal growth factor receptor: a new target for anticancer therapy

6 September 2017

1 reference

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Tyrosine kinase inhibitors: from rational design to clinical trials

6 September 2017

1 reference

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The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

6 September 2017

1 reference

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6-Substituted-4-(3-bromophenylamino)quinazolines as putative irreversible inhibitors of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases with enhanced antitumor activity

6 September 2017

1 reference

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Oncogenic kinase signalling

6 September 2017

1 reference

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

6 September 2017

1 reference

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Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

6 September 2017

1 reference

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Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases

6 September 2017

1 reference

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ZD1839 ('Iressa') as an anticancer agent

6 September 2017

1 reference

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Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents

6 September 2017

1 reference

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The pursuit of optimal outcomes in cancer therapy in a new age of rationally designed target-based anticancer agents

6 September 2017

1 reference

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PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

6 September 2017

1 reference

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Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

6 September 2017

1 reference

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

6 September 2017

1 reference

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Consumption of EGF by A431 cells: evidence for receptor recycling

6 September 2017

1 reference

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Epidermal growth factor-related peptides and their receptors in human malignancies

6 September 2017

1 reference

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Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

6 September 2017

1 reference

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Genistein, a specific inhibitor of tyrosine-specific protein kinases

6 September 2017

1 reference

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Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

6 September 2017

1 reference

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Tyrphostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Receptor-binding, biodistribution, and metabolism studies of 64Cu-DOTA-cetuximab, a PET-imaging agent for epidermal growth-factor receptor-positive tumors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Characterization of compound 584, an Abl kinase inhibitor with lasting effects

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

In vivo and in vitro uptake of 111In, delivered with the affibody molecule (ZEGFR:955)2, in EGFR expressing tumour cells.

14 September 2017

1 reference

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Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors.

14 September 2017

1 reference

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Cellular studies of binding, internalization and retention of a radiolabeled EGFR-binding affibody molecule

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

(89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Novel iodine-124 labeled EGFR inhibitors as potential PET agents for molecular imaging in cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Novel carbon-11 labeled 4-dimethylamino-but-2-enoic acid [4-(phenylamino)-quinazoline-6-yl]-amides: potential PET bioprobes for molecular imaging of EGFR-positive tumors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Tyrosine kinase inhibition: an approach to drug development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Potential (18)F-labeled biomarkers for epidermal growth factor receptor tyrosine kinase.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

A tyrosine-specific protein kinase inhibitor, alpha-cyano-3-ethoxy-4-hydroxy-5-phenylthiomethylcinnamamide, blocks the phosphorylation of tyrosine kinase substrate in intact cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Panitumumab with irinotecan/leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

EKB-569, a new irreversible epidermal growth factor receptor tyrosine kinase inhibitor, with clinical activity in patients with non-small cell lung cancer with acquired resistance to gefitinib

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Radiosynthesis of ML03, a novel positron emission tomography biomarker for targeting epidermal growth factor receptor via the labeling synthon: [11C]acryloyl chloride

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Labeled EGFr-TK irreversible inhibitor (ML03): in vitro and in vivo properties, potential as PET biomarker for cancer and feasibility as anticancer drug.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

The effect of quercetin on the phosphorylatio activity of the Rous sarcoma virus transforming gene product in vitro and in vivo

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778093

The effect of the [18F]-PEG group on tracer qualification of [4-(phenylamino)-quinazoline-6-YL]-amide moiety--an EGFR putative irreversible inhibitor

2 September 2018

1 reference

12 December 2020

Effects of combination anti-vascular endothelial growth factor receptor and anti-epidermal growth factor receptor therapies on the growth of gastric cancer in a nude mouse model

1 reference

12 December 2020

Regulation of protein kinases activity by quercetin in Ehrlich ascites tumor cells

1 reference

12 December 2020

Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3

1 reference

12 December 2020

In situ inhibition of tyrosine protein kinase by erbstatin

1 reference

12 December 2020

Specific inhibitors of tyrosine-specific protein kinases: properties of 4-hydroxycinnamamide derivatives in vitro

1 reference

12 December 2020

Imaging of human tumor xenografts with an indium-111-labeled anti-epidermal growth factor receptor monoclonal antibody

1 reference

12 December 2020

Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus

1 reference

12 December 2020

Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumab

1 reference

12 December 2020

Targeting tyrosine kinases in cancer: the second wave

1 reference

12 December 2020

Synthesis of [11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase

1 reference

12 December 2020

10.2174/138161208786404326

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

release_vcnntk3ehvaohpvymfxga35syi

26 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vcnntk3ehvaohpvymfxga35syi

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18991714%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

18991714

1 reference