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CCN family of proteins: critical modulators of the tumor cell microenvironment.
scientific article published on 12 August 2016
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5055503
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20 March 2020
title
CCN family of proteins: critical modulators of the tumor cell microenvironment
(English)
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5055503
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20 March 2020
main subject
protein family
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author
Herman Yeger
series ordinal
1
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Europe PubMed Central
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5055503
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27517291%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
author name string
Bernard Perbal
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2
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Europe PubMed Central
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5055503
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12 August 2016
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20 March 2020
published in
Journal of Cell Communication and Signaling
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20 March 2020
volume
10
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20 March 2020
page(s)
229-240
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Europe PubMed Central
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20 March 2020
issue
3
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Europe PubMed Central
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20 March 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s12079-016-0346-6
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6 September 2017
CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer
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6 September 2017
CCN5: biology and pathophysiology
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Connective tissue growth factor: context-dependent functions and mechanisms of regulation
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CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease
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6 September 2017
The CCN family of proteins: structure-function relationships
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6 September 2017
Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage
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6 September 2017
CCN3/nephroblastoma overexpressed matricellular protein regulates integrin expression, adhesion, and dissemination in melanoma
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retrieved
6 September 2017
Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
New insight into CCN3 interactions--nuclear CCN3 : fact or fantasy?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
CCN proteins and cancer: two to tango
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
Expression of connective tissue growth factor (CCN2) in desmoplastic small round cell tumour
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
The expression of ccn3(nov) gene in musculoskeletal tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
Differential expression of the ccn3 (nov) proto-oncogene in human prostate cell lines and tissues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
Nuclear localisation of NOVH protein: a potential role for NOV in the regulation of gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
6 September 2017
The CCN family of genes: a perspective on CCN biology and therapeutic potential
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
14 September 2017
The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
14 September 2017
Role of WISP3 siRNA in proliferation, apoptosis and invasion of bladder cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
14 September 2017
Prognostic value of CCN3 in osteosarcoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
14 September 2017
Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
14 September 2017
Patterns of specific genomic alterations associated with poor prognosis in high-grade renal cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
28 September 2017
Report on the 8th international workshop on the CCN family of genes - Nice November 3-8, 2015.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
26 June 2018
The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
26 June 2018
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
26 June 2018
CCN3: a key growth regulator in Chronic Myeloid Leukaemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
26 June 2018
Extracellular matrix microarrays to study inductive signaling for endoderm specification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
CCN2 and CCN5 exerts opposing effect on fibroblast proliferation and transdifferentiation induced by TGF-β.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Evaluation of extracellular matrix protein CCN1 as a prognostic factor for glioblastoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Novel and recurrent mutations in WISP3 and an atypical phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Association of Wnt-Inducible Signaling Pathway Protein 1 Genetic Polymorphisms With Lung Cancer Susceptibility and Platinum-Based Chemotherapy Response.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Expression of CCN family members correlates with the clinical features of hepatocellular carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Connective tissue growth factor is a new ligand of epidermal growth factor receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
A comparative study of clinicopathological significance, FGFBP1, and WISP-2 expression between squamous cell/adenosquamous carcinomas and adenocarcinoma of the gallbladder
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
CCN3 regulates proliferation and migration properties in Jeg3 trophoblast cells via ERK1/2, Akt and Notch signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Wnt/beta-catenin pathway deregulation in childhood adrenocortical tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5055503
retrieved
2 September 2018
Matricellular protein CCN1 (CYR61) expression is associated with high-grade ductal carcinoma in situ
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27517291
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S12079-016-0346-6
1 reference
stated in
Europe PubMed Central
PMCID
5055503
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27517291%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Fatcat ID
release_pmza27grdbhmthosm4alno52lu
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/pmza27grdbhmthosm4alno52lu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
5055503
1 reference
stated in
Europe PubMed Central
PMCID
5055503
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27517291%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PubMed ID
27517291
1 reference
stated in
Europe PubMed Central
PMCID
5055503
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27517291%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
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