(Q37323577)

19 August 2017

Reactor design for large scale suspension animal cell culture (English)

1 reference

19 August 2017

J Varley

1

1 reference

PMCID

3463394

19 August 2017

J Birch

series ordinal

2

1 reference

19 August 2017

1 May 1999

1 reference

19 August 2017

1 reference

19 August 2017

29

1 reference

19 August 2017

3

1 reference

19 August 2017

177-205

1 reference

https://scigraph.springernature.com/pub.10.1023/a:1008008021481

19 August 2017

0 references

cites work

Bubble bed reactor: A reactor design to minimize the damage of bubble aeration on animal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Effects of stirring and sparging on cultured hybridoma cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Equipment and procedures for production of monoclonal antibodies in culture

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 1. Analysis of data from controlled batch reactors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Media additives for protecting freely suspended animal cells against agitation and aeration damage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Potential and problems of animal cells in suspension culture

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Cells and bubbles in sparged bioreactors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Perfusion culture apparatus for suspended mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Scale-up considerations and bioreactor development for animal cell cultivation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Problems in scale-up of biotechnology production processes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Dextran as protectant against damage caused by sparging for hybridoma cells in a bubble column

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Utilization of osmoprotective compounds by hybridoma cells exposed to hyperosmotic stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Effect of low serum concentrations (0%-2.5%) on growth, production, and shear sensitivity of hybridoma cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Effects of ammonia and lactate on hybridoma growth, metabolism, and antibody production

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Oxygen transfer in animal cell culture medium

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Effects of abrupt and gradual osmotic stress on antibody production and content in hybridoma cells that differ in production kinetics

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Production of human alkaline phosphatase, a secreted, glycosylated protein, from a baculovirus expression system and the attachment-dependent cell line Trichoplusia ni BTI-Tn 5B1-4 using a split-flow, air-lift bioreactor

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Safety and economic aspects of continuous mammalian cell culture

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor. 2. Effects of medium components and waste products

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Large scale production of recombinant mouse and rat growth hormone by fed-batch GS-NSO cell cultures

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Nutrient enrichment and in-situ waste removal through electrical means for hybridoma cultures

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Intracellular responses of productive hybridomas subjected to high osmotic pressure

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Death mechanisms of animal cells in conditions of intensive agitation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Ammonia affects the glycosylation patterns of recombinant mouse placental lactogen-I by chinese hamster ovary cells in a pH-dependent manner

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Scale-up on basis of structured mixing models: A new concept.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

The influence of vessel height and top-section size on the hydrodynamic characteristics of airlift fermentors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Quantification of damage to suspended insect cells as a result of bubble rupture.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Substantial overproduction of antibodies by applying osmotic pressure and sodium butyrate

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Estimation of disruption of animal cells by laminar shear stress.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

The influence of fluid mixing upon respiratory patterns for extended growth of a methylotroph in an air-lift fermenter.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

A comparison of large-scale Sf9 insect cell growth and protein production: stirred vessel vs. airlift

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463394

Development of a strategy to control the dissolved concentrations of oxygen and carbon dioxide at constant shear in a plant cell bioreactor

2 September 2018

1 reference

12 December 2020

Large-scale production of monoclonal antibodies in suspension culture

1 reference

12 December 2020

Oxygen transfer in liquids

1 reference

12 December 2020

Damage mechanisms of suspended animal cells in agitated bioreactors with and without bubble entrainment

1 reference

12 December 2020

Cultivation of hybridoma cells in an inclined bioreactor

1 reference

12 December 2020

CO(2) in large-scale and high-density CHO cell perfusion culture

1 reference

12 December 2020

Cell inactivation in the presence of sparging and mechanical agitation

1 reference

12 December 2020

Animal cells in turbulent fluids: Details of the physical stimulus and the biological response

1 reference

12 December 2020

Evidence for posttranscriptional stimulation of monoclonal antibody secretion by L-glutamine during slow hybridoma growth

1 reference

12 December 2020

Gas holdup and overall volumetric oxygen transfer coefficient in airlift contactors

1 reference

12 December 2020

Cultivation of E. coli in single- and ten-stage tower-loop reactors

1 reference

12 December 2020

Oxygen transfer properties of bubbles in animal cell culture media

1 reference

12 December 2020

Oxygen transfer in a pulse bioreactor

1 reference

12 December 2020

Use of surface aerator improve oxygen transfer in cell culture

1 reference

12 December 2020

Growth and oxygen requirements of antibody producing mouse hybridoma cells in suspension culture

1 reference

12 December 2020

Lethal events during gas sparging in animal cell culture

1 reference

12 December 2020

Cultivation of mammalian cells as aggregates in bioreactors: effect of calcium concentration of spatial distribution of viability

1 reference

12 December 2020

Hydrodynamics and mixing in a multiple air-lift loop reactor

1 reference

12 December 2020

Effect of medium osmolarity on hybridoma growth, metabolism, and antibody production

1 reference

12 December 2020

Dissolved oxygen concentration profiles in a production-scale bioreactor

1 reference

12 December 2020

Characterization of the two-phase systems in airlift tower-loop bioreactors during the cultivation of E. coli

1 reference

12 December 2020

Homogenisation and oxygen transfer rates in large agitated and sparged animal cell bioreactors: Some implications for growth and production

1 reference

12 December 2020

Effect of silicone antifoam on shear sensitivity of hybridoma cells in sparged cultures

1 reference

12 December 2020

Integrated design for mammalian cell culture

1 reference

12 December 2020

Effects of paddle impeller geometry on power input and mass transfer in small-scale animal cell culture vessels

1 reference

12 December 2020

Enhancement of monoclonal antibody production by immobilized hybridoma cell culture with hyperosmolar medium

1 reference

12 December 2020

In-situ removal of ammonium and lactate through electrical means for hybridoma cultures

1 reference

12 December 2020

Very large scale suspension cultures of mammalian cells

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1008008021481

1 reference

PMCID

3463394

Dimensions Publication ID

19 August 2017

0 references

1 reference

19 August 2017

1 reference

PMCID

3463394