(Q37324308)

19 August 2017

1 reference

title

Biological repair of the degenerated intervertebral disc by the injection of growth factors (English)

1 reference

19 August 2017

Koichi Masuda

1

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19 August 2017

13 November 2008

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19 August 2017

European Spine Journal

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19 August 2017

17 Suppl 4

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19 August 2017

441-451

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https://scigraph.springernature.com/pub.10.1007/s00586-008-0749-z

19 August 2017

0 references

cites work

Pharmacological enhancement of disc diffusion and differentiation of healthy, ageing and degenerated discs : Results from in-vivo serial post-contrast MRI studies in 365 human lumbar discs

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Prevention of disc degeneration with growth factors

6 September 2017

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Biologic modification of animal models of intervertebral disc degeneration

6 September 2017

1 reference

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Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model

6 September 2017

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Cellular therapy for disc degeneration

6 September 2017

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Tumor necrosis factor-alpha modulates matrix production and catabolism in nucleus pulposus tissue

6 September 2017

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

6 September 2017

1 reference

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Growth factors and treatment of intervertebral disc degeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Nutrition of the intervertebral disc

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Growth factors and the intervertebral disc

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Collagen and proteoglycan abnormalities in the GDF-5-deficient mice and molecular changes when treating disk cells with recombinant growth factor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells.

6 September 2017

1 reference

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2000 Volvo Award winner in basic science studies: Exogenous tumor necrosis factor-alpha mimics nucleus pulposus-induced neuropathology. Molecular, histologic, and behavioral comparisons in rats

6 September 2017

1 reference

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Morphogenetic messages are in the extracellular matrix: biotechnology from bench to bedside

6 September 2017

1 reference

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A morphological and histological study of the postnatal development of intervertebral discs in the lumbar spine of the rabbit

6 September 2017

1 reference

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The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells

6 September 2017

1 reference

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Anti-apoptotic effects of IGF-1 and PDGF on human intervertebral disc cells in vitro

14 September 2017

1 reference

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Tumor necrosis factor alpha and nucleus-pulposus-induced nerve root injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Reproducible long-term disc degeneration in a large animal model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Human nucleus pulposis can respond to a pro-inflammatory stimulus

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Human intervertebral disc cells from the annulus: three-dimensional culture in agarose or alginate and responsiveness to TGF-beta1.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Stimulation of mature canine intervertebral disc by growth factors

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Radiographic and histologic effects of chondroitinase ABC on normal canine lumbar intervertebral disc

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

An in vivo model of reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertebral disc

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Recombinant human osteogenic protein-1 upregulates proteoglycan metabolism of human anulus fibrosus and nucleus pulposus cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

The in vivo biological effects of intradiscal recombinant human bone morphogenetic protein-2 on the injured intervertebral disc: an animal experiment.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Tissue-engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF-beta1 in platelet-rich plasma.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Platelet-rich plasma (PRP) stimulates the extracellular matrix metabolism of porcine nucleus pulposus and anulus fibrosus cells cultured in alginate beads.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Osteogenic protein-1 (osteogenic protein-1/bone morphogenetic protein-7) inhibits degeneration and pain-related behavior induced by chronically compressed nucleus pulposus in the rat.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Osteogenic protein-1 is most effective in stimulating nucleus pulposus and annulus fibrosus cells to repair their matrix after chondroitinase ABC-induced in vitro chemonucleolysis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

ISSLS prize winner: A study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

In vivo growth factor treatment of degenerated intervertebral discs

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Disc chondrocyte transplantation in a canine model: a treatment for degenerated or damaged intervertebral disc

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

The effect of bone morphogenetic protein-2 on rat intervertebral disc cells in vitro

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Recombinant osteogenic protein-1 upregulates extracellular matrix metabolism by rabbit annulus fibrosus and nucleus pulposus cells cultured in alginate beads.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587664

The effects of chondroitinase ABC on the rabbit intervertebral disc. A roentgenographic and histologic study

2 September 2018

1 reference

12 December 2020

Nucleolysis of the rabbit intervertebral disc using chondroitinase ABC

1 reference

12 December 2020

Serial changes observed by magnetic resonance imaging in the intervertebral disc after chemonucleolysis. A consideration of the mechanism of chemonucleolysis

1 reference

12 December 2020

Effects of chondroitinase ABC on degenerative intervertebral discs

1 reference

12 December 2020

Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2

1 reference

12 December 2020

Experimental chemonucleolysis with chondroitinase ABC in monkeys

1 reference

12 December 2020

Autocrine/paracrine mechanism of insulin-like growth factor-1 secretion, and the effect of insulin-like growth factor-1 on proteoglycan synthesis in bovine intervertebral discs

1 reference

12 December 2020

Chemonucleolytic effects of chondroitinase ABC on normal rabbit intervertebral discs. Course of action up to 10 days postinjection and minimum effective dose

1 reference

12 December 2020

Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study

1 reference

12 December 2020

Percutaneous reinsertion of the nucleus pulposus. An experimental study

1 reference

12 December 2020

Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: an in vitro and in vivo experimental study

1 reference

12 December 2020

Investigation of the short-term effect of chemonucleolysis with chondroitinase ABC

1 reference

12 December 2020

mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs

1 reference

12 December 2020

Osteogenic protein-1 enhances matrix replenishment by intervertebral disc cells previously exposed to interleukin-1

1 reference

12 December 2020

An in vivo model of degenerative disc disease

1 reference

12 December 2020

Expression and Distribution of Tumor Necrosis Factor Alpha in Human Lumbar Intervertebral Discs: A Study in Surgical Specimen and Autopsy Controls

1 reference

12 December 2020

Intradiscal injections of osteogenic protein-1 restore the viscoelastic properties of degenerated intervertebral discs

1 reference

12 December 2020

Effects of growth differentiation factor-5 on the intervertebral disc--in vitro bovine study and in vivo rabbit disc degeneration model study

1 reference

12 December 2020

Anti-catabolic effect of OP-1 in chronically compressed intervertebral discs

1 reference

12 December 2020

Experimental intervertebral disc degeneration induced by chondroitinase ABC in the goat

1 reference

12 December 2020

10.1007/S00586-008-0749-Z

Identifiers

DOI

1 reference

19 August 2017

1 reference

PMC publication ID

2587664

19 August 2017

PubMed publication ID

19005698

1 reference

PMC publication ID

2587664