(Q37326531)

19 August 2017

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title

Insulin-like growth factor-I and bone: lessons from mice and men. (English)

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19 August 2017

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Masanobu Kawai

1

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PubMed ID

19011906

19 August 2017

Clifford J Rosen

series ordinal

2

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PubMed ID

19011906

19 August 2017

language of work or name

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15 November 2008

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19 August 2017

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19 August 2017

24

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19 August 2017

7

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19 August 2017

1277-1285

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https://scigraph.springernature.com/pub.10.1007/s00467-008-1040-6

19 August 2017

0 references

cites work

Insulin-like growth factors and bone: the osteoporosis connection

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00467-008-1040-6

Circulating levels of IGF-1 directly regulate bone growth and density

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00467-008-1040-6

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00467-008-1040-6

Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring adipogenic differentiation

21 January 2018

1 reference

12 December 2020

Sibling pair linkage and association studies between bone mineral density and the insulin-like growth factor I gene locus

1 reference

12 December 2020

IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts.

1 reference

12 December 2020

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

1 reference

12 December 2020

Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice

1 reference

12 December 2020

Insulin-like growth factor I and bone mineral density: experience from animal models and human observational studies

1 reference

12 December 2020

Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study

1 reference

12 December 2020

PPARG by dietary fat interaction influences bone mass in mice and humans

1 reference

12 December 2020

Reduced bone mineral content in adult patients with growth hormone deficiency

1 reference

12 December 2020

Normal growth and development in the absence of hepatic insulin-like growth factor I

1 reference

12 December 2020

A Whole-Genome Linkage Scan Suggests Several Genomic Regions Potentially Containing Quantitative Trait Loci for Osteoporosis

1 reference

12 December 2020

A novel mutation in a patient with insulin-like growth factor 1 (IGF1) deficiency

1 reference

12 December 2020

Mechanisms of disease: is osteoporosis the obesity of bone?

1 reference

12 December 2020

Clinical and functional characteristics of the human Arg59Ter insulin-like growth factor i receptor (IGF1R) mutation: implications for a gene dosage effect of the human IGF1R.

1 reference

12 December 2020

Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation

1 reference

12 December 2020

Perturbations in Bone Formation and Resorption in Insulin-Like Growth Factor Binding Protein-3 Transgenic Mice

1 reference

12 December 2020

Growth enhancement of transgenic mice expressing human insulin-like growth factor I

1 reference

12 December 2020

Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover

1 reference

12 December 2020

Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women

1 reference

12 December 2020

Reduced bone mineral density in patients with adult onset growth hormone deficiency.

1 reference

12 December 2020

Effects of long-term treatment with growth hormone on bone and mineral metabolism in children with growth hormone deficiency

1 reference

12 December 2020

Paracrine Overexpression of IGFBP‐4 in Osteoblasts of Transgenic Mice Decreases Bone Turnover and Causes Global Growth Retardation

1 reference

12 December 2020

Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells

1 reference

12 December 2020

Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa

1 reference

12 December 2020

No major effect of the insulin-like growth factor I gene on bone mineral density in premenopausal Chinese women

1 reference

12 December 2020

Lifelong accumulation of bone in mice lacking Pten in osteoblasts

1 reference

12 December 2020

The relationship among serum insulin-like growth factor-I, insulin-like growth factor-I gene polymorphism, and bone mineral density in postmenopausal women in Korea

1 reference

12 December 2020

Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo

1 reference

12 December 2020

Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the Framingham Study

1 reference

12 December 2020

Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion

1 reference

12 December 2020

Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program

1 reference

12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

1 reference

12 December 2020

Mutation at cleavage site of insulin-like growth factor receptor in a short-stature child born with intrauterine growth retardation.

1 reference

12 December 2020

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

1 reference

12 December 2020

Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo

1 reference

12 December 2020

Are adult patients with Laron syndrome osteopenic? A comparison between dual-energy X-ray absorptiometry and volumetric bone densities

1 reference

12 December 2020

Homozygous and heterozygous expression of a novel insulin-like growth factor-I mutation

1 reference

12 December 2020

Umbilical venous IGF-1 concentration, neonatal bone mass, and body composition.

1 reference

12 December 2020

Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling

1 reference

12 December 2020

Expression profile of osteoblast lineage at defined stages of differentiation.

1 reference

12 December 2020

The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study

1 reference

12 December 2020

1,25-Dihydroxyvitamin D3 increases secretion of insulin-like growth factor binding protein-4 (IGFBP-4) by human osteoblast-like cells in vitro and elevates IGFBP-4 serum levels in vivo

1 reference

12 December 2020

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

1 reference

12 December 2020

Postnatal growth and bone mass in mice with IGF-I haploinsufficiency.

1 reference

12 December 2020

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1 reference

12 December 2020

Adipocyte differentiation from the inside out

1 reference

12 December 2020

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

1 reference

12 December 2020

The skeletal structure of insulin-like growth factor I-deficient mice

1 reference

12 December 2020

Bone is a target for the antidiabetic compound rosiglitazone.

1 reference

12 December 2020

Bone mineral, histomorphometry, and body composition in adults with growth hormone receptor deficiency.

1 reference

12 December 2020

Inhibitory Insulin-Like Growth Factor-Binding Protein: Cloning, Complete Sequence, and Physiological Regulation

1 reference

12 December 2020

IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation

1 reference

12 December 2020

Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway.

1 reference

12 December 2020

Mapping quantitative trait loci for serum insulin-like growth factor-1 levels in mice

1 reference

12 December 2020

Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study

1 reference

12 December 2020

Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study

1 reference

12 December 2020

Role of IGF-I signaling in regulating osteoclastogenesis

1 reference

12 December 2020

Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene

1 reference

12 December 2020

Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

1 reference

12 December 2020

Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.

1 reference

12 December 2020

A chromosomal inversion within a quantitative trait locus has a major effect on adipogenesis and osteoblastogenesis

1 reference

12 December 2020

Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin.

1 reference

12 December 2020

Effects of recombinant insulin-like growth factor-I and growth hormone on bone turnover in elderly women

1 reference

12 December 2020

10.1007/S00467-008-1040-6

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19011906