(Q37329052)

19 August 2017

1 reference

title

Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects (English)

1 reference

19 August 2017

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1 reference

Shigeaki Suzuki

1

1 reference

19 August 2017

Kortaro Tanaka

series ordinal

2

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19 August 2017

Norihiro Suzuki

series ordinal

3

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19 August 2017

19 November 2008

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Journal of Cerebral Blood Flow & Metabolism

19 August 2017

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19 August 2017

29

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19 August 2017

464-479

1 reference

19 August 2017

3

1 reference

Multiple levels of regulation of the interleukin-6 system in stroke

19 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 in biology and medicine

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Ischemia-Induced Interleukin-6 as a Potential Endogenous Neuroprotective Cytokine against NMDA Receptor-Mediated Excitoxicity in the Brain

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Leukemia inhibitory factor is expressed in astrocytes following cortical brain injury

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Inflammatory mediators and stroke: new opportunities for novel therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS).

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The role of STATs in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Leukemia inhibitory factor is a key signal for injury-induced neurogenesis in the adult mouse olfactory epithelium.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 and interleukin-1 receptor antagonist in acute stroke

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of IL-6 in the ischemic penumbra

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Signalling through the JAK-STAT pathway in the developing brain

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The –174G/C Polymorphism of the Interleukin 6 Gene Is a Hallmark of Lacunar Stroke and Not Other Ischemic Stroke Phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Upregulation of gp130 and STAT3 activation in the rat hippocampus following transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Lack of interleukin-6 expression is not protective against focal central nervous system ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Leukemia inhibitory factor participates in the expansion of neural stem/progenitors after perinatal hypoxia/ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 expression in exo-focal neurons after striatal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Pathobiology of ischaemic stroke: an integrated view

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitro

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Increased cytokine release from peripheral blood cells after acute stroke.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Proinflammatory genetic profiles in subjects with history of ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Ebselen lowers plasma interleukin-6 levels and glial heme oxygenase-1 expression after focal photothrombotic brain ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Genetic Polymorphisms and the Risk of Stroke After Cardiac Surgery

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Suppression of Stat3 promotes neurogenesis in cultured neural stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of CNTF/LIF-receptor components and activation of STAT3 signaling in axotomized facial motoneurons: evidence for a sequential postlesional function of the cytokines

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The many faces of tumor necrosis factor in stroke

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Experimental axonal injury triggers interleukin-6 mRNA, protein synthesis and release into cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The Role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Temporal modulation of cytokine expression following focal cerebral ischemia in mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

LIF: lots of interesting functions

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Inflammation in stroke and focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Cerebral ischemia and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Activation of the JAK/STAT pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

TNF-alpha -308G/A and IL-6 -174 G/C polymorphisms in the Turkish pediatric stroke patients

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin 6 primes human neutrophil and monocyte oxidative burst response

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Ischemic preconditioning-induced expression of gp130 and STAT3 in astrocytes of the rat hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Ciliary neurotrophic factor attenuates spatial cognition impairment, cortical infarction and thalamic degeneration in spontaneously hypertensive rats with focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Polymorphisms of the inflammatory system and risk of ischemic cerebrovascular events.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Quantitative changes in interleukin proteins following focal stroke in the rat

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Leukemia inhibitory factor (LIF) mRNA-expressing neuronal subpopulations in adult rat basal forebrain

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 is not expressed in activated microglia and in reactive astrocytes in response to lesion of rat basal forebrain cholinergic system as demonstrated by combined in situ hybridization and immunocytochemistry

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Concomitant mobilization of plasma cells and hematopoietic progenitors into peripheral blood of patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Inflammation and atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha (CNTFR alpha) expression following focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 prevents ischemia-induced learning disability and neuronal and synaptic loss in gerbils.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Effects of kainic acid on messenger RNA levels of IL-1 beta, IL-6, TNF alpha and LIF in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of interleukin-6 receptor, leukemia inhibitory factor receptor and glycoprotein 130 in the murine cerebellum and neuropathological effect of leukemia inhibitory factor on cerebellar Purkinje cells

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Inflammation and ischaemic stroke.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Nature of the retrograde signal from injured nerves that induces interleukin-6 mRNA in neurons

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Effect of CNTF on ischaemic cell damage in rat hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1beta and interleukin-6 in the rat hippocampus after transient global ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Differential regulation of ciliary neurotrophic factor and its receptor in the rat hippocampus following transient global ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Signalling pathways mediating inflammatory responses in brain ischaemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Induction of Stat3, a signal transducer and transcription factor, in reactive microglia following transient focal cerebral ischaemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Studies of Plasmodium falciparum cytoadherence using immortalized human brain capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Stromelysin-1 and Interleukin-6 Gene Promoter Polymorphisms Are Determinants of Asymptomatic Carotid Artery Atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Brain endothelial cell production of a neuroprotective cytokine, interleukin-6, in response to noxious stimuli

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Induction of interleukin-6 by depolarization of neurons.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

JAK2 and STAT3 activation contributes to neuronal damage following transient focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of interleukin 6 in the rat striatum following stereotaxic injection of quinolinic acid.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Transcriptional regulation of neurogenesis: potential mechanisms in cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Stimulation of interleukin-6 secretion and gene transcription in primary astrocytes by adenosine.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Multiple molecular penumbras after focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

The ciliary neurotrophic factor/leukemia inhibitory factor/gp130 receptor complex operates in the maintenance of mammalian forebrain neural stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Induction of gp130-related Cytokines and Activation of JAK2/STAT3 Pathway in Astrocytes Precedes Up-regulation of Glial Fibrillary Acidic Protein in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Distribution of the transcription factor signal transducer and activator of transcription 3 in the rat central nervous system and dorsal root ganglia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Temporal profile and cellular localization of interleukin-6 protein after focal cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Cerebral neurons express interleukin-6 after transient forebrain ischemia in gerbils.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Immunohistochemical detection of leukemia inhibitory factor after focal cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of interleukin-6 is suppressed by inhibition of voltage-sensitive Na+/Ca2+ channels after cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Phosphorylation of signal transducer and activator of transcription-3 (Stat3) after focal cerebral ischemia in rats.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 promotes post-traumatic healing in the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Gp130 and the interleukin-6 family of cytokines

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Alteration of second messengers during acute cerebral ischemia - adenylate cyclase, cyclic AMP-dependent protein kinase, and cyclic AMP response element binding protein

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Phosphorylation of cyclic adenosine monophosphate response element binding protein in oligodendrocytes in the corpus callosum after focal cerebral ischemia in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 expression and regulation in astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Proinflammatory cytokines and early neurological worsening in ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 receptor expression and localization after transient global ischemia in gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

IL-6: an early marker for outcome in acute ischemic stroke.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Expression of interleukin-6, c-fos, and zif268 mRNAs in rat ischemic cortex

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Characteristic localization of gp130 (the signal-transducing receptor component used in common for IL-6/IL-11/CNTF/LIF/OSM) in the rat brain

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Role of the interleukin-6 -174 G>C gene polymorphism in retinal artery occlusion

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Induction of phosphorylated-Stat3 following focal cerebral ischemia in mice.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Higher levels of interleukin-6 are associated with lower echogenicity of carotid artery plaques.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Localization of mRNA for leukemia inhibitory factor receptor in the adult rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons.

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2008.141

7 January 2021

Identifiers

DOI

10.1038/JCBFM.2008.141

1 reference

release_4zxb7qth35f37fjgfsteymj3b4

19 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4zxb7qth35f37fjgfsteymj3b4

24 November 2022

mapped directly with Wikidata item

1 reference