(Q37329290)

19 August 2017

Synthetic studies on Et-743. Assembly of the pentacyclic core and a formal total synthesis (English)

1 reference

19 August 2017

Dan Fishlock

1

1 reference

19 August 2017

Robert M Williams

series ordinal

2

1 reference

19 August 2017

language of work or name

English

0 references

publication date

1 December 2008

1 reference

Journal of Organic Chemistry

19 August 2017

1 reference

19 August 2017

73

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19 August 2017

24

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19 August 2017

9594-9600

1 reference

Regioselectivity of Pictet-Spengler Cyclization Reactions to Construct the Pentacyclic Frameworks of the Ecteinascidin-Saframycin Class of Tetrahydroisoquinoline Antitumor Antibiotics.

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Antitumor activity of tetrahydroisoquinoline analogues 3-epi-jorumycin and 3-epi-renieramycin G.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Chemistry and biology of the tetrahydroisoquinoline antitumor antibiotics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Synthesis of ecteinascidin ET-743 and phthalascidin Pt-650 from cyanosafracin B

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Antitumor compounds from tunicates

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Bioactive compounds from aquatic and terrestrial sources

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Molecular mechanism of action of 5,6-dihydroxytryptamine. Synthesis and biological evaluation of 4-methyl-, 7-methyl-, and 4,7-dimethyl-5,6-dihydroxytryptamines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Stereospecific formal total synthesis of ecteinascidin 743.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Asymmetric total syntheses of (-)-jorumycin, (-)-renieramycin G, 3-epi-jorumycin, and 3-epi-renieramycin G.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Synthetic studies toward ecteinascidin 743.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Synthetic studies on ecteinascidin 743: rapid access to the fully functionalized tetrahydroisoquinoline with a bridged 10-membered sulfur containing macrocycle

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

Total synthesis of ecteinascidin 743.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736329

A New, More Efficient, and Effective Process for the Synthesis of a Key Pentacyclic Intermediate for Production of Ecteinascidin and Phthalascidin Antitumor Agents

2 September 2018

1 reference

12 December 2020

Synthetic studies on ecteinascidin-743: constructing a versatile pentacyclic intermediate for the synthesis of ecteinascidins and saframycins

1 reference

12 December 2020

Total synthesis of (-)-tetrazomine. Determination of the stereochemistry of tetrazomine and the synthesis and biological activity of tetrazomine analogues

1 reference

12 December 2020

Total Synthesis of (-)-Tetrazomine and Determination of Its Stereochemistry This work was supported by the National Institutes of Health (Grant CA85419). We are grateful to Yamanouchi Pharmaceutical Co. for providing a generous gift of natural tetra

1 reference

12 December 2020

Molecular and crystal structures of ecteinascidins: potent antitumor compounds from the Caribbean tunicate Ecteinascidia turbinata

1 reference

12 December 2020

Asymmetric total synthesis of (-)-cribrostatin 4 (renieramycin H)

1 reference

12 December 2020

Total synthesis of ecteinascidin 743

1 reference

12 December 2020

Total synthesis of the marine natural product (-)-cribrostatin 4 (renieramycin H)

1 reference

12 December 2020

Synthetic studies on Et-743. Asymmetric, stereocontrolled construction of the tetrahydroisoquinoline core via radical cyclization on a glyoxalimine

1 reference

12 December 2020

KF-Silica as a stationary phase for the chromatographic removal of tin residues from organic compounds

1 reference

12 December 2020

Identifiers

DOI

10.1021/JO801159K

1 reference

release_rmssqaxt75ef5g4vfphg4mq7tq

19 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rmssqaxt75ef5g4vfphg4mq7tq

24 November 2022

mapped directly with Wikidata item

1 reference

19 August 2017

PubMed publication ID

18687003

1 reference