(Q37332744)

19 August 2017

Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors (English)

1 reference

19 August 2017

Stephanie Wickham

1

1 reference

19 August 2017

Nicholas Regan

2

1 reference

19 August 2017

Matthew B West

3

1 reference

19 August 2017

Justin Thai

4

1 reference

19 August 2017

Paul F Cook

5

1 reference

19 August 2017

Simon S Terzyan

6

1 reference

19 August 2017

Pui Kai Li

7

1 reference

19 August 2017

Marie H Hanigan

8

1 reference

19 August 2017

language of work or name

English

0 references

publication date

1 March 2013

1 reference

19 August 2017

1 reference

19 August 2017

450

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19 August 2017

3

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19 August 2017

547-557

1 reference

Divergent effects of compounds on the hydrolysis and transpeptidation reactions of γ-glutamyl transpeptidase

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Cysteinyl leukotrienes and their receptors: molecular and functional characteristics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Lung lining fluid glutathione attenuates IL-13-induced asthma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Kinetic characterization and identification of the acylation and glycosylation sites of recombinant human gamma-glutamyltranspeptidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Chemical toxicology of reactive intermediates formed by the glutathione-dependent bioactivation of halogen-containing compounds

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Mechanism for acivicin inactivation of triad glutamine amidotransferases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Extracellular glutathione is a source of cysteine for cells that express gamma-glutamyl transpeptidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Inhibition of gamma-glutamyl transpeptidase activity by acivicin in vivo protects the kidney from cisplatin-induced toxicity.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Characterization and Physiological Function of Rat Renal γ-Glutamyltranspeptidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Serine-borate complex as a transition-state inhibitor of gamma-glutamyl transpeptidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Hydrolysis and transfer reactions catalyzed by γ-glutamyl transpeptidase; Evidence for separate substrate sites and for high affinity of L-cystine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

γ-glutamyltransferase of rat kidney. Simultaneous assay of the hydrolysis and transfer reactions with (glutamate-14C)glutathione

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Design, synthesis, and evaluation of gamma-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of gamma-glutamyl transpeptidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Phase I trial and pharmacokinetics of acivicin administered by 72-hour infusion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Probing the donor and acceptor substrate specificity of the γ-glutamyl transpeptidase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Gamma-glutamyl-glutathione. Natural occurrence and enzymology.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Gamma-glutamyl transpeptidase substrate specificity and catalytic mechanism

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836663

Gamma Glutamyl Transferase and Metabolic Syndrome, Cardiovascular Disease, and Mortality Risk

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20121435

Accumulation of DNA damage in the organs of mice deficient in γ-glutamyltranspeptidase

21 January 2018

1 reference

12 December 2020

Quantitative analysis and interpretation of allosteric behavior

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Gamma-glutamyl transpeptidase

1 reference

12 December 2020

Phase II trial of acivicin in advanced metastatic breast cancer

1 reference

12 December 2020

Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20121435

1 reference

release_g6nbhefgezczxg7ukxqzfc7bcm

19 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/g6nbhefgezczxg7ukxqzfc7bcm

24 November 2022

mapped directly with Wikidata item

1 reference

19 August 2017

1 reference