(Q37333827)

English

Leptin regulates KATP channel trafficking in pancreatic β-cells by a signaling mechanism involving AMP-activated protein kinase (AMPK) and cAMP-dependent protein kinase (PKA).

scientific article published on 07 October 2013

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27 February 2020

Leptin regulates KATP channel trafficking in pancreatic β-cells by a signaling mechanism involving AMP-activated protein kinase (AMPK) and cAMP-dependent protein kinase (PKA) (English)

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27 February 2020

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27 February 2020

author name string

Yelena N Kryukova

2

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27 February 2020

Show-Ling Shyng

3

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7 October 2013

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27 February 2020

Journal of Biological Chemistry

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27 February 2020

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27 February 2020

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27 February 2020

34098-34109

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27 February 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3837151/fullTextXML

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Actin dynamics regulated by the balance of neuronal Wiskott-Aldrich syndrome protein (N-WASP) and cofilin activities determines the biphasic response of glucose-induced insulin secretion

1 reference

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6 September 2017

Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic β-cells

1 reference

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6 September 2017

K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration

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BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures

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1 reference

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AMP-activated protein kinase connects cellular energy metabolism to KATP channel function

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A role of the sulfonylurea receptor 1 in endocytic trafficking of ATP-sensitive potassium channels

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PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis

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AMP-activated protein kinase attenuates nitric oxide-induced beta-cell death

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6 September 2017

Hypothalamic CaMKK2 contributes to the regulation of energy balance

1 reference

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6 September 2017

Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.

1 reference

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6 September 2017

Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism

1 reference

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6 September 2017

Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

1 reference

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The actin filament and dendritic peptide release

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6 September 2017

Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice

1 reference

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6 September 2017

Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue

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6 September 2017

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

6 September 2017

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

6 September 2017

KATP channels as molecular sensors of cellular metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

6 September 2017

ATP-sensitive potassium channelopathies: focus on insulin secretion

1 reference

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6 September 2017

Peptide tags for labeling membrane proteins in live cells with multiple fluorophores

1 reference

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6 September 2017

The AMP-activated protein kinase pathway--new players upstream and downstream.

1 reference

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6 September 2017

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

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6 September 2017

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

6 September 2017

PIP3, PIP2, and cell movement--similar messages, different meanings?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

6 September 2017

The adipoinsular axis: effects of leptin on pancreatic beta-cells

1 reference

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6 September 2017

Molecular biology of adenosine triphosphate-sensitive potassium channels

1 reference

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6 September 2017

Membrane phospholipid control of nucleotide sensitivity of KATP channels

1 reference

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6 September 2017

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

1 reference

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6 September 2017

Octameric stoichiometry of the KATP channel complex

1 reference

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6 September 2017

Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells

1 reference

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6 September 2017

Human leptin levels are pulsatile and inversely related to pituitary-adrenal function.

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Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells

1 reference

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14 September 2017

Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the K(ATP) channel and insulin secretion in rats.

1 reference

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Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels

1 reference

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Leptin activates AMP-activated protein kinase in hepatic cells via a JAK2-dependent pathway

1 reference

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14 September 2017

Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

14 September 2017

Leptin activation of ATP-sensitive K+ (KATP) channels in rat CRI-G1 insulinoma cells involves disruption of the actin cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

28 September 2017

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

1 reference

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28 September 2017

Essential role of phosphoinositide 3-kinase in leptin-induced K(ATP) channel activation in the rat CRI-G1 insulinoma cell line.

1 reference

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PKA-mediated phosphorylation of the human K(ATP) channel: separate roles of Kir6.2 and SUR1 subunit phosphorylation.

1 reference

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28 September 2017

Role of tyrosine phosphorylation in leptin activation of ATP-sensitive K+ channels in the rat insulinoma cell line CRI-G1.

1 reference

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28 September 2017

Leptin activates ATP-sensitive potassium channels in the rat insulin-secreting cell line, CRI-G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

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28 September 2017

Obesity and the beta cell: lessons from leptin

1 reference

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28 September 2017

PIP2 and PIP as determinants for ATP inhibition of KATP channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

26 June 2018

Leptin: a potent inhibitor of insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

26 June 2018

Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons

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2 September 2018

Retinoic acid leads to cytoskeletal rearrangement through AMPK-Rac1 and stimulates glucose uptake through AMPK-p38 MAPK in skeletal muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

2 September 2018

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

2 September 2018

Leptin reduces glucose transport and cellular ATP levels in INS-1 beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

2 September 2018

The insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

2 September 2018

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1 reference

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2 September 2018

ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837151

2 September 2018

Effects of cytochalasin D and latrunculin B on mechanical properties of cells.

1 reference

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2 September 2018

Subunit stoichiometry of the pancreatic β-cell ATP-sensitive K+ channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.516880

21 January 2018

A role for neuronal KATP channels in metabolic control of the seizure gate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.516880

21 January 2018

Deleterious effect of dithizone-DMSO staining on insulin secretion in rat and human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/24100028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association and stoichiometry of K(ATP) channel subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/24100028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pancreatic -cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/24100028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24100028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose recruits K(ATP) channels via non-insulin-containing dense-core granules

1 reference

https://pubmed.ncbi.nlm.nih.gov/24100028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.516880

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24100028%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24100028%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24100028%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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