(Q37336895)

2 July 2019

review article

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title

Enhancing aromatic L-amino acid decarboxylase activity: implications for L-DOPA treatment in Parkinson's disease (English)

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2 July 2019

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Maria Hadjiconstantinou

series ordinal

1

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2 July 2019

Norton H Neff

series ordinal

2

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2 July 2019

publication date

1 January 2008

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2 July 2019

CNS Neuroscience & Therapeutics

published in

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2 July 2019

volume

14

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2 July 2019

issue

4

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2 July 2019

page(s)

340-351

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2 July 2019

Treatment of Parkinsonism With Levodopa

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Microdialysis study of the effects of the antiparkinsonian drug budipine on L-DOPA-induced release of dopamine and 5-hydroxytryptamine by rat substantia nigra and corpus striatum

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12 December 2020

Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET study

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Regulation of dopaminergic activity in early Parkinson's disease

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Effect of memantine (NMDA antagonist) on Parkinson's disease: a double-blind crossover randomized study

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Stimulation of dopa decarboxylase activity in striatum of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine

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12 December 2020

Immunocytochemical characterization of catecholaminergic neurons in the rat striatum following dopamine-depleting lesions

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12 December 2020

Dual effects of L-3,4-dihydroxyphenylalanine on aromatic L-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: evidence that behaviour is dopamine independent

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12 December 2020

In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease

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12 December 2020

Opposite effects of glutamate antagonists and antiparkinsonian drugs on the activities of DOPA decarboxylase and 5-HTP decarboxylase in the rat brain

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12 December 2020

Phosphorylation and activation of brain aromatic L-amino acid decarboxylase by cyclic AMP-dependent protein kinase

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12 December 2020

Clozapine and risperidone treatment of psychosis in Parkinson's disease

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12 December 2020

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12 December 2020

Dyskinesias and motor fluctuations in Parkinson's disease. A community-based study.

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12 December 2020

Continuous dopamine-receptor stimulation in early Parkinson's disease

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12 December 2020

MK801 influences L-DOPA-induced dopamine release in intact and hemi-parkinson rats

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12 December 2020

6-(18)F-DOPA PET study in patients with schizophrenia. Positron emission tomography

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12 December 2020

SCH 23390 enhances exogenous L-DOPA decarboxylation in nigrostriatal neurons

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12 December 2020

Mechanisms of the effects of exogenous levodopa on the dopamine-denervated striatum

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12 December 2020

Acute neuroleptic stimulates DOPA decarboxylase in porcine brain in vivo

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12 December 2020

Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study

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12 December 2020

18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease

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12 December 2020

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Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen

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12 December 2020

A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: an 18F-dopa PET study

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12 December 2020

Amantadine in Parkinson's disease

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12 December 2020

Quetiapine versus clozapine: a preliminary report of comparative effects on dopaminergic psychosis in patients with Parkinson's disease.

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12 December 2020

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12 December 2020

Progression of dopaminergic hypofunction in striatal subregions in Parkinson's disease using [18F]CFT PET.

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12 December 2020

Localization and functional significance of striatal neurons immunoreactive to aromatic L-amino acid decarboxylase or tyrosine hydroxylase in rat Parkinsonian models

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12 December 2020

Amantadine increases L-DOPA-derived extracellular dopamine in the striatum of 6-hydroxydopamine-lesioned rats

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12 December 2020

Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines

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12 December 2020

Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study

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12 December 2020

Effect of ritanserin, a highly selective 5-HT2 receptor antagonist, on Parkinson's disease

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12 December 2020

Clozapine prevents recurrence of psychosis in Parkinson's disease

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12 December 2020

Changes in dopa decarboxylase mRNA but not tyrosine hydroxylase mRNA levels in rat brain following antipsychotic treatment

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12 December 2020

Parallel upregulation of catecholamine-synthesizing enzymes in rat brain and adrenal gland: effects of reserpine and correlation with immediate early gene expression

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12 December 2020

The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia

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12 December 2020

Efficacy of memantine, an NMDA receptor antagonist, in the treatment of Parkinson's disease.

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12 December 2020

Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells

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12 December 2020

Does Nefazodone Improve Both Depression and Parkinson Disease? A Pilot Randomized Trial

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12 December 2020

The sensitivity of 18-fluorodopa positron emission tomography and magnetic resonance imaging in Parkinson's disease

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12 December 2020

Continuous dopaminergic stimulation in early and advanced Parkinson's disease

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12 December 2020

Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats

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12 December 2020

Quetiapine and clozapine in parkinsonian patients with dopaminergic psychosis

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12 December 2020

Functional interactions between somatodendritic dopamine release, glutamate receptors and brain-derived neurotrophic factor expression in mesencephalic structures of the brain

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12 December 2020

Levodopa and the progression of Parkinson's disease

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12 December 2020

Aromatic L-amino acid decarboxylase (AAAD) activity in rhesus macaque striatum after MAO-B inhibition by Ro 16-6491.

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12 December 2020

Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004

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12 December 2020

Other pharmacological treatments for motor complications and dyskinesias

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12 December 2020

Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA.

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12 December 2020

The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.

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12 December 2020

Dopamine-glutamate reciprocal modulation of release and motor responses in the rat caudate-putamen and nucleus accumbens of "intact" animals

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12 December 2020

Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum

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12 December 2020

Modulation of [18F]fluorodopa (FDOPA) kinetics in the brain of healthy volunteers after acute haloperidol challenge

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12 December 2020

Striatal subregional 6-[18F]fluoro-L-dopa uptake in early Parkinson's disease: a two-year follow-up study

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12 December 2020

Imaging in Parkinson's disease: the role of monoamines in behavior

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12 December 2020

Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

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12 December 2020

Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission

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12 December 2020

Regulation of aromatic L-amino acid decarboxylase by dopamine receptors in the rat brain

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12 December 2020

Levodopa-induced dyskinesias

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12 December 2020

Extrastriatal monoamine neuron function in Parkinson's disease: an 18F-dopa PET study.

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12 December 2020

Differential recovery of dopamine synthetic enzymes following MPTP and the consequences of GM1 ganglioside treatment.

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12 December 2020

The metabolism of exogenous L-dopa in the brain: an immunohistochemical study of its conversion to dopamine in non-catecholaminergic cells of the rat brain

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12 December 2020

Modulation of retinal aromatic L-amino acid decarboxylase via alpha 2 adrenoceptors

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12 December 2020

Striatal neurons with aromatic L-amino acid decarboxylase-like immunoreactivity in the rat

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12 December 2020

Aromatic L-amino acid decarboxylase activity of the rat retina is modulated in vivo by environmental light

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12 December 2020

Adjuvant treatment of Parksinson's disease with budipine: a double-blind trial versus placebo.

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12 December 2020

Exposure to light accelerates the formation of dopamine from exogenous L-dopa in the rat retina.

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12 December 2020

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12 December 2020

Nonaminergic striatal neurons convert exogenous l-dopa to dopamine in parkinsonism

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12 December 2020

Clinical and [18F] dopa PET findings in early Parkinson's disease

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12 December 2020

Analysis of the Neuronal Promoter of the Rat Aromatic l‐Amino Acid Decarboxylase Gene

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12 December 2020

The Human Aromatic l‐Amino Acid Decarboxylase Gene Can Be Alternatively Spliced To Generate Unique Protein Isoforms

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12 December 2020

Regulation of DOPA decarboxylase activity in brain of living rat.

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12 December 2020

Mianserin treatment of patients with psychosis induced by antiparkinsonian drugs

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12 December 2020

Dizocilpine enhances striatal tyrosine hydroxylase and aromatic L-amino acid decarboxylase activity

1 reference

12 December 2020

Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease

1 reference

12 December 2020

Distribution of aromatic L-amino acid decarboxylase mRNA in mouse brain by in situ hybridization histology

1 reference

12 December 2020

Suppression of dyskinesias in advanced Parkinson's disease: moderate daily clozapine doses provide long-term dyskinesia reduction

1 reference

12 December 2020

Phorbol ester administration transiently increases aromatic L-amino acid decarboxylase activity of the mouse striatum and midbrain

1 reference

12 December 2020

Induction of aromatic L-amino acid decarboxylase mRNA by interleukin-1 beta and prostaglandin E2 in PC12 cells

1 reference

12 December 2020

Regulation of striatal aromatic L-amino acid decarboxylase: effects of blockade or activation of dopamine receptors

1 reference

12 December 2020

Modulatory effect of clozapine on levodopa response in Parkinson's disease: a preliminary study

1 reference

12 December 2020

NSD-1015 alters the gene expression of aromatic L-amino acid decarboxylase in rat PC12 pheochromocytoma cells

1 reference

12 December 2020

Evidence for cyclic AMP-mediated increase of aromatic L-amino acid decarboxylase activity in the striatum and midbrain

1 reference

12 December 2020

Structure of the rat aromatic L-amino acid decarboxylase gene: evidence for an alternative promoter usage

1 reference

12 December 2020

Parallel up-regulation of catecholamine biosynthetic enzymes by dexamethasone in PC12 cells

1 reference

12 December 2020

Nocturnal akathisia in Parkinson's disease: treatment with clozapine.

1 reference

12 December 2020

Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors

1 reference

12 December 2020

Aromatic L-amino acid decarboxylase immunoreactive cells in the rat striatum: a possible site for the conversion of exogenous L-DOPA to dopamine

1 reference

12 December 2020

An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease.

1 reference

12 December 2020

Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme

1 reference

12 December 2020

D2 dopamine receptor antisense increases the activity and mRNA of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in mouse brain.

1 reference

12 December 2020

Modulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase after inhibiting monoamine oxidase-A.

1 reference

12 December 2020

Differential effects of levodopa on dopaminergic function in early and advanced Parkinson's disease.

1 reference

12 December 2020

Regulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase by dopaminergic drugs.

1 reference

12 December 2020

Does phenylethylamine have a role in schizophrenia?: LSD and PCP up-regulate aromatic L-amino acid decarboxylase mRNA levels

1 reference

12 December 2020

In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain

1 reference

12 December 2020

The significance of continuous dopaminergic stimulation in the treatment of Parkinson's disease.

1 reference

12 December 2020

Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET.

1 reference

12 December 2020

Enhanced [3H]DOPA and [3H]dopamine turnover in striatum and frontal cortex in vivo linked to glutamate receptor antagonism

1 reference

12 December 2020

Differential effects of NMDA and non-NMDA antagonists on the activity of aromatic L-amino acid decarboxylase activity in the nigrostriatal dopamine pathway of the rat.

1 reference

12 December 2020

Low dosage clozapine effects on L-dopa induced dyskinesias in parkinsonian patients

1 reference

12 December 2020

Clozapine use in Parkinson's disease: a retrospective analysis of a large multicentered clinical experience.

1 reference

12 December 2020

The antiparkinsonian drug budipine stimulates the activity of aromatic L-amino acid decarboxylase and enhances L-DOPA-induced dopamine release in rat substantia nigra

1 reference

12 December 2020

Parallel modulation of striatal dopamine synthetic enzymes by second messenger pathways

1 reference

12 December 2020

Effects of glutamate antagonists on the activity of aromatic L-amino acid decarboxylase

1 reference

12 December 2020

Role of excitatory amino acids in the regulation of dopamine synthesis and release in the neostriatum

1 reference

12 December 2020

10.1111/J.1755-5949.2008.00058.X

Identifiers

DOI

1 reference

2 July 2019

PMC publication ID

6494005

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2 July 2019

PubMed publication ID

19040557

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2 July 2019