(Q37344225)

19 August 2017

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title

The importance of the intrarenal renin-angiotensin system (English)

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19 August 2017

Juan Carlos Q Velez

1

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19 August 2017

publication date

9 December 2008

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Nature Clinical Practice Nephrology

19 August 2017

published in

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19 August 2017

volume

5

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19 August 2017

issue

2

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19 August 2017

page(s)

89-100

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Enhanced expression of Ang-(1-7) during pregnancy

19 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Effects of truncated angiotensins in humans after double blockade of the renin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Renal angiotensin II concentration and interstitial infiltration of immune cells are correlated with blood pressure levels in salt-sensitive hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Implications of species difference for clinical investigation: studies on the renin-angiotensin system

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Cathepsin B is a prorenin processing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Differential ANG II generation in plasma and tissue of mice with decreased expression of the ACE gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Characterization of neutral endopeptidase 24.11 in dog glomeruli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Effects of different angiotensins during acute, double blockade of the renin system in conscious dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Renal microvascular actions of angiotensin II fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

Antihypertensive therapy with MK 421: angiotensin II--renin relationships to evaluate efficacy of converting enzyme blockade

21 January 2018

1 reference

12 December 2020

Functional expression of the renin-angiotensin system in human podocytes

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12 December 2020

Tissue-specific expression of renin-angiotensin system components in IgA nephropathy

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12 December 2020

Aldosterone enhances renin gene expression in juxtaglomerular cells

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12 December 2020

Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension

1 reference

12 December 2020

Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes.

1 reference

12 December 2020

Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms

1 reference

12 December 2020

Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles

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12 December 2020

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12 December 2020

Aminopeptidase A activity and angiotensin III effects on [Ca2+]i along the rat nephron

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12 December 2020

Effects of ACE inhibition on proximal tubule sodium transport

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12 December 2020

Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via a NO/cGMP-dependent pathway

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12 December 2020

Quantification of human angiotensinogen by a novel sandwich ELISA.

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12 December 2020

Why are angiotensin concentrations so high in the kidney?

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12 December 2020

Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats

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12 December 2020

Effects of angiotensin-(1-7) and other bioactive components of the renin-angiotensin system on vascular resistance and noradrenaline release in rat kidney

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12 December 2020

Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors

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12 December 2020

Cell surface aminopeptidase A and N activities in human glomerular epithelial cells

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12 December 2020

Renal expression of matrix metalloproteinases in human ANCA-associated glomerulonephritis

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12 December 2020

Identification and proteomic profiling of exosomes in human urine

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12 December 2020

In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system

1 reference

12 December 2020

Aliskiren combined with losartan in type 2 diabetes and nephropathy

1 reference

12 December 2020

AT1 receptor-activated signaling mediates angiotensin IV-induced renal cortical vasoconstriction in rats

1 reference

12 December 2020

Involvement of the pancreatic renin-angiotensin system in insulin resistance and the metabolic syndrome

1 reference

12 December 2020

Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trial

1 reference

12 December 2020

Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats.

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12 December 2020

Distribution of neutral endopeptidase activity along the rat and rabbit nephron

1 reference

12 December 2020

Expression of aminopeptidase A, an angiotensinase, in glomerular mesangial cells

1 reference

12 December 2020

Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney

1 reference

12 December 2020

Kidney aminopeptidase A and hypertension, part II: effects of angiotensin II

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12 December 2020

Activation of a local renin angiotensin system in podocytes by glucose

1 reference

12 December 2020

Renal expression of aminopeptidase A in rats with two-kidney, one-clip hypertension

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12 December 2020

Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells

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12 December 2020

Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats.

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12 December 2020

Angiotensin II receptors in rabbit renal preglomerular vessels

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12 December 2020

A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli

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12 December 2020

Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta

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12 December 2020

RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney.

1 reference

12 December 2020

Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats

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12 December 2020

Renin-angiotensin system-regulating aminopeptidase activities are modified in the pineal gland of rats with breast cancer induced by N-methyl-nitrosourea

1 reference

12 December 2020

Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren

1 reference

12 December 2020

Genetic deletion of AT1a receptors attenuates intracellular accumulation of ANG II in the kidney of AT1a receptor-deficient mice

1 reference

12 December 2020

L-158,809 and (D-Ala(7))-angiotensin I/II (1-7) decrease PAI-1 release from human umbilical vein endothelial cells

1 reference

12 December 2020

Does angiotensin (1-7) contribute to the anti-proteinuric effect of ACE-inhibitors

1 reference

12 December 2020

Direct renin inhibitors: the dawn of a new era, or just a variation on a theme?

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12 December 2020

Quantification of conversion and degradation of circulating angiotensin in rats.

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12 December 2020

Localization of carboxypeptidase A-like enzyme in rat kidney

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12 December 2020

Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes

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12 December 2020

Aminopeptidase N reduces basolateral Na+ -K+ -ATPase in proximal tubule cells

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12 December 2020

Biological properties of the angiotensin peptides other than angiotensin II: implications for hypertension and cardiovascular diseases

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12 December 2020

Overexpression of angiotensinogen increases tubular apoptosis in diabetes

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12 December 2020

Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls

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12 December 2020

Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation.

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12 December 2020

Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats

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12 December 2020

Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system

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12 December 2020

Immunoelectron microscopic single and double labelling of aminopeptidase N (CD 13) and dipeptidyl peptidase IV (CD 26)

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12 December 2020

Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.

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12 December 2020

Hypertension and angiotensin II hypersensitivity in aminopeptidase A-deficient mice.

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12 December 2020

Enzymatic properties of human aminopeptidase A. Regulation of its enzymatic activity by calcium and angiotensin IV

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12 December 2020

In vitro production of angiotensin II by isolated glomeruli

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12 December 2020

Synthesis and effects of active fragments of angiotensin II.

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12 December 2020

Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats

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12 December 2020

The renin-angiotensin system in the mammalian central nervous system.

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12 December 2020

Antenatal Membranous Glomerulonephritis Due to Anti–Neutral Endopeptidase Antibodies

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12 December 2020

Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor.

1 reference

12 December 2020

Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor

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12 December 2020

AT1 and AT2 receptor in the kidney: role in health and disease

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12 December 2020

High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells

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12 December 2020

Mouse glomerular epithelial cells in culture with features of podocytes in vivo express aminopeptidase A and angiotensinogen but not other components of the renin-angiotensin system.

1 reference

12 December 2020

Angiotensin-(1-7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors

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12 December 2020

Autoradiographic analysis and regulation of angiotensin receptor subtypes AT(4), AT(1), and AT((1-7)) in the kidney

1 reference

12 December 2020

Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

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12 December 2020

Angiotensin I-to-II conversion in the human renal vascular bed

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12 December 2020

Angiotensin and cell growth: a link to cardiovascular hypertrophy?

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12 December 2020

Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.

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12 December 2020

The role of angiotensin(1-7) in renal vasculature of the rat.

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12 December 2020

Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat.

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12 December 2020

The (pro)renin receptor: pathophysiological roles in cardiovascular and renal pathology

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12 December 2020

Documentation of angiotensin II receptors in glomerular epithelial cells

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12 December 2020

Role of angiotensin II generated by angiotensin converting enzyme-independent pathways in canine kidney.

1 reference

12 December 2020

Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism

1 reference

12 December 2020

Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats

1 reference

12 December 2020

Angiotensinase A gene expression and enzyme activity in isolated glomeruli of diabetic rats

1 reference

12 December 2020

Transforming growth factor-beta and angiotensin II: the missing link from glomerular hyperfiltration to glomerulosclerosis?

1 reference

12 December 2020

Involvement of (pro)renin receptor in the glomerular filtration barrier

1 reference

12 December 2020

Possible involvement of aminopeptidase A in hypertension and renal damage in Dahl salt-sensitive rats

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12 December 2020

ACE and ACE2 activity in diabetic mice.

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12 December 2020

Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury

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12 December 2020

Renal ACE2 expression in human kidney disease

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12 December 2020

Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose

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12 December 2020

Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats

1 reference

12 December 2020

Differential regulation of angiotensin peptide levels in plasma and kidney of the rat

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12 December 2020

Enhancement of intrarenal angiotensin II levels in 2 kidney 1 clip and angiotensin II induced hypertension

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12 December 2020

Differential regulation of elevated renal angiotensin II in chronic renal ischemia

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12 December 2020

Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations

1 reference

12 December 2020

Local adipose tissue renin-angiotensin system

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12 December 2020

Differential actions of renal ischemic injury on the intrarenal angiotensin system

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12 December 2020

Renin and angiotensinogen gene expression in maturing rat kidney

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12 December 2020

Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats

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12 December 2020

Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ-induced diabetic rats

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12 December 2020

Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system

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12 December 2020

Activation of the renin-angiotensin system within podocytes in diabetes

1 reference

12 December 2020

Antihypertensive therapy with aliskiren

1 reference

12 December 2020

ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice.

1 reference

12 December 2020

Angiotensin converting enzyme-independent angiotensin ii production by chymase is up-regulated in the ischemic kidney in renovascular hypertension

1 reference

12 December 2020

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

1 reference

12 December 2020

Tissue angiotensin system in cardiovascular medicine. A paradigm shift?

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12 December 2020

Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats

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12 December 2020

The paradox of the low-renin state in diabetic nephropathy

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12 December 2020

Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II

1 reference

12 December 2020

(Des-Asp1) Angiotensin I: A Study of its Pressor and Steroidogenic Activities in Conscious Rats*

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12 December 2020

Interactions between angiotensin II and NF-kappaB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy.

1 reference

12 December 2020

Gene expression of the renin-angiotensin system in human kidney

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12 December 2020

The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules

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12 December 2020

Chymase-like angiotensin II-generating activity in end-stage human autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor

1 reference

12 December 2020

Angiotensin II production and distribution in the kidney--II. Model-based analysis of experimental data

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12 December 2020

Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor

1 reference

12 December 2020

Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure

1 reference

12 December 2020

Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus

1 reference

12 December 2020

Renal ACE immunohistochemical localization in NIDDM patients with nephropathy

1 reference

12 December 2020

Angiotensin II compartmentalization within the kidney: effects of salt diet and blood pressure alterations

1 reference

12 December 2020

AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases

1 reference

12 December 2020

The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group

1 reference

12 December 2020

Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease

1 reference

12 December 2020

Vanadate and fluoride effects on Na+-K+-Cl- cotransport in squid giant axon

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

7 January 2021

inferred from DOI database lookup

Electrically silent potassium channel subunits from human lens epithelium

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

7 January 2021

inferred from DOI database lookup

Antihypertensive Therapy with MK 4211

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH1015

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCPNEPH1015

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19 August 2017

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