(Q37347828)

English

CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation

scientific article published on 05 January 2016

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

0 references

0 references

author name string

J Liu

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

C Gao

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

W Chen

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

W Ma

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

X Li

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Y Shi

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

H Zhang

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

L Zhang

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Y Long

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

H Xu

10

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

X Guo

11

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

S Deng

12

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

X Yan

13

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

D Yu

14

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

G Pan

15

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Y Chen

16

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

L Lai

17

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

W Liao

18

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Z Li

19

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

5 January 2016

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Translational Psychiatry

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

e703

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Reprogramming patient-derived cells to study the epilepsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Effectiveness of antiepileptic drug combination therapy for partial-onset seizures based on mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

RNA-guided human genome engineering via Cas9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Nontruncating SCN1A mutations associated with severe myoclonic epilepsy of infancy impair cell surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Dravet syndrome history

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

A TALE nuclease architecture for efficient genome editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Epileptogenic ion channel mutations: From bedside to bench and, hopefully, back again

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

NaV1.1 channels and epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Truly "rational" polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Noninactivating voltage-gated sodium channels in severe myoclonic epilepsy of infancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Genetic mechanisms that underlie epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Epilepsy-associated dysfunction in the voltage-gated neuronal sodium channel SCN1A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Molecular basis of an inherited epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Origin of GABAergic neurons in the human neocortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Severe myoclonic epilepsy of infancy: extended spectrum of GEFS+?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Generalized epilepsy with febrile seizures plus. A genetic disorder with heterogeneous clinical phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

6 September 2017

Mosaic SCN1A mutations in familial partial epilepsy with antecedent febrile seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

2 September 2018

Nonfunctional SCN1A is common in severe myoclonic epilepsy of infancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

2 September 2018

Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

2 September 2018

Nav1.1 channels with mutations of severe myoclonic epilepsy in infancy display attenuated currents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

2 September 2018

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068877

2 September 2018

Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/26731440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulatory proteins can rescue a trafficking defective epileptogenic Nav1.1 Na+ channel mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/26731440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/TP.2015.203

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37347828&oldid=2200207706"