(Q37352287)

English

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter

scientific article published on January 2009

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter (English)

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Europe PubMed Central

PMC publication ID

19 August 2017

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positron emission tomography

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author name string

Fanxing Zeng

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jiyoung Mun

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Nachwa Jarkas

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jeffrey S Stehouwer

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Ronald J Voll

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Gilles D Tamagnan

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Leonard Howell

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

John R Votaw

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Clinton D Kilts

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Charles B Nemeroff

10

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Europe PubMed Central

PMC publication ID

19 August 2017

Mark M Goodman

11

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Europe PubMed Central

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19 August 2017

language of work or name

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publication date

1 January 2009

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Europe PubMed Central

PMC publication ID

19 August 2017

Journal of Medicinal Chemistry

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Europe PubMed Central

PMC publication ID

19 August 2017

52

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Europe PubMed Central

PMC publication ID

19 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

62-73

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

(R)-N-Methyl-3-(3-(125)I-pyridin-2-yloxy)-3-phenylpropan-1-amine: a novel probe for norepinephrine transporters

1 reference

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6 September 2017

Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

6 September 2017

Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C

1 reference

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6 September 2017

Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors

1 reference

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6 September 2017

Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

6 September 2017

Synthesis and binding affinities of fluoroalkylated raloxifenes

1 reference

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6 September 2017

An apparatus and behavioral training protocol to conduct positron emission tomography (PET) neuroimaging in conscious rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

6 September 2017

The role of the locus coeruleus in the development of Parkinson's disease

1 reference

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6 September 2017

Attention-deficit/hyperactivity disorder (ADHD) as a noradrenergic disorder

1 reference

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6 September 2017

Role of norepinephrine in the pathophysiology and treatment of mood disorders

1 reference

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6 September 2017

Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites

1 reference

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6 September 2017

Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter

1 reference

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6 September 2017

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

14 September 2017

Molecular physiology of norepinephrine and serotonin transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

14 September 2017

Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

26 June 2018

Relationship between lipophilicity and brain extraction of C-11-labeled radiopharmaceuticals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

26 June 2018

3Hnisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

26 June 2018

Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Imaging the norepinephrine transporter with positron emission tomography: initial human studies with (S,S)-[18F]FMeNER-D2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Imaging the norepinephrine transporter in humans with (S,S)-[11C]O-methyl reboxetine and PET: problems and progress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

In vivo assessment of [11C]MRB as a prospective PET ligand for imaging the norepinephrine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Synthesis and evaluation of radioiodinated (S,S)-2-(alpha-(2-iodophenoxy)benzyl)morpholine for imaging brain norepinephrine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Synthesis, enantiomeric resolution, F-18 labeling and biodistribution of reboxetine analogs: promising radioligands for imaging the norepinephrine transporter with positron emission tomography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Isoflurane alters the amount of dopamine transporter expressed on the plasma membrane in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Selective binding of 2-[125I]iodo-nisoxetine to norepinephrine transporters in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Evaluation of a new norepinephrine transporter PET ligand in baboons, both in brain and peripheral organs

1 reference

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2 September 2018

Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

Synthesis and in vivo evaluation of novel radiotracers for the in vivo imaging of the norepinephrine transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746395

2 September 2018

PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter

1 reference

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2 September 2018

Synthesis of 11C/13C-labelled prostacyclins

1 reference

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2 September 2018

Synthesis of 11C-labeled desipramine and its metabolite 2-hydroxydesipramine: potential radiotracers for PET studies of the norepinephrine transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/19067522

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoradiographic analysis of [3H]desmethylimipramine binding in the human brain postmortem

1 reference

https://pubmed.ncbi.nlm.nih.gov/19067522

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norepinephrine transporter sites are decreased in the locus coeruleus in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19067522

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfones as Radical Progenitors: An Unprecedented Example of Homolytic Sulfone Cleavage Facilitated by o-Stannyl Substitution of Aryl Sulfones(1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19067522

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric synthesis of (+)-(S,S)-reboxetine via a new (S)-2-(hydroxymethyl)morpholine preparation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19067522

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM800817H

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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