(Q37356028)

English

Human immunodeficiency virus type 1 V1-to-V5 envelope variants from the chronic phase of infection use CCR5 and fuse more efficiently than those from early after infection.

scientific article published on 22 July 2009

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3 February 2020

Human immunodeficiency virus type 1 V1-to-V5 envelope variants from the chronic phase of infection use CCR5 and fuse more efficiently than those from early after infection (English)

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3 February 2020

Brenda Kwambana

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3 February 2020

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Behzad Etemad

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Angela Fellows

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Anupa Kamat

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Yang Feng

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Sandra Lee

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22 July 2009

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3 February 2020

Journal of Virology

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3 February 2020

9694-9708

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3 February 2020

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.

1 reference

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Natural variation in the V3 crown of human immunodeficiency virus type 1 affects replicative fitness and entry inhibitor sensitivity

1 reference

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Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome

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Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virus

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Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

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Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

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Comparative study of adaptive molecular evolution in different human immunodeficiency virus groups and subtypes

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Infection with Multiple Human Immunodeficiency Virus Type 1 Variants Is Associated with Faster Disease Progression

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Role of the human immunodeficiency virus type 1 envelope gene in viral fitness.

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Antibody neutralization and escape by HIV-1

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

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Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES

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Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.

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Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

1 reference

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Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

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Increased replication of non-syncytium-inducing HIV type 1 isolates in monocyte-derived macrophages is linked to advanced disease in infected children

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HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use

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HIV-1 sequence variation: drift, shift, and attenuation

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Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection

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Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates

1 reference

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Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences.

1 reference

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Variants from the diverse virus population identified at seroconversion of a clade A human immunodeficiency virus type 1-infected woman have distinct biological properties

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A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

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Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression.

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

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A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

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In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5.

1 reference

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Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

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Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies

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Viral dynamics in human immunodeficiency virus type 1 infection

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26 June 2018

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1 reference

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1 reference

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2 September 2018

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1 reference

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HIV type 1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748008

2 September 2018

Selection forces and constraints on retroviral sequence variation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748008

2 September 2018

CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748008

2 September 2018

In vitro replication kinetics of human immunodeficiency virus type 1 (HIV-1) variants in relation to virus load in long-term survivors of HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748008

2 September 2018

Restriction of HIV Type 1 Infection in Macrophages Heterozygous for a Deletion in the CC-Chemokine Receptor 5 Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748008

3 December 2018

Surface CD4 Is Critical to in Vitro HIV Infection of Human Alveolar Macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748008

3 December 2018

Chemokine receptor regulation and HIV type 1 tropism in monocyte-macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/19625411

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for human peripheral blood monocyte isolation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19625411

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00925-09

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19625411%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19625411%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19625411%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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