(Q37357076)

English

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).

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scholarly article

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29 February 2020

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530) (English)

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29 February 2020

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29 February 2020

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29 February 2020

Noriomi Matsumura

8

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29 February 2020

author name string

R Y-J Huang

1

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29 February 2020

M K Wong

2

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29 February 2020

K T Kuay

4

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29 February 2020

A H C Ng

5

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29 February 2020

Y-S Chu

7

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29 February 2020

H-C Lai

9

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29 February 2020

Y F Lee

10

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29 February 2020

W-J Sim

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29 February 2020

C Chai

12

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29 February 2020

E Pietschmann

13

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29 February 2020

S Mori

14

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29 February 2020

J J H Low

15

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29 February 2020

M Choolani

16

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29 February 2020

J P Thiery

17

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29 February 2020

publication date

7 November 2013

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29 February 2020

Cell Death and Disease

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29 February 2020

4

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29 February 2020

e915

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29 February 2020

copyright license

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

1 November 2013

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April 2022 Public Data File from Crossref

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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

1 reference

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6 September 2017

Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis

1 reference

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6 September 2017

Early events in cell adhesion and polarity during epithelial-mesenchymal transition.

1 reference

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6 September 2017

Epithelial-mesenchymal transition in ovarian carcinoma

1 reference

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6 September 2017

Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT).

1 reference

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6 September 2017

A cell-based small molecule screening method for identifying inhibitors of epithelial-mesenchymal transition in carcinoma

1 reference

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6 September 2017

Slug and Sox9 cooperatively determine the mammary stem cell state

1 reference

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6 September 2017

Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2.

1 reference

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6 September 2017

ZEB2 upregulates integrin α5 expression through cooperation with Sp1 to induce invasion during epithelial-mesenchymal transition of human cancer cells

1 reference

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6 September 2017

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

1 reference

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6 September 2017

TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Integrated genomic analyses of ovarian carcinoma

1 reference

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6 September 2017

Hallmarks of Cancer: The Next Generation

1 reference

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6 September 2017

Target cell movement in tumor and cardiovascular diseases based on the epithelial-mesenchymal transition concept

1 reference

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6 September 2017

Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity

1 reference

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6 September 2017

Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

ZEB1-responsive genes in non-small cell lung cancer

1 reference

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6 September 2017

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

1 reference

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6 September 2017

Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells

1 reference

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6 September 2017

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells

1 reference

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6 September 2017

Metastasis: alone or together?

1 reference

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6 September 2017

Epithelial-mesenchymal transitions in development and disease

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6 September 2017

Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

1 reference

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6 September 2017

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

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6 September 2017

Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm.

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6 September 2017

Vimentin and epithelial-mesenchymal transition in human breast cancer--observations in vitro and in vivo.

1 reference

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6 September 2017

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

1 reference

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6 September 2017

Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis

1 reference

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6 September 2017

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 reference

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6 September 2017

The NCI60 human tumour cell line anticancer drug screen

1 reference

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6 September 2017

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Complex networks orchestrate epithelial-mesenchymal transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Epithelial-mesenchymal transitions in tumour progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Disruption of epithelial cell-matrix interactions induces apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

6 September 2017

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

14 September 2017

An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

14 September 2017

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

14 September 2017

Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

14 September 2017

Hepatocyte growth factor activator inhibitor type 1 regulates epithelial to mesenchymal transition through membrane-bound serine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847320

14 September 2017

Switching in discoid domain receptor expressions in SLUG-induced epithelial-mesenchymal transition

1 reference

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14 September 2017

Lysophosphatidic acid induces ovarian cancer cell dispersal by activating Fyn kinase associated with p120-catenin

1 reference

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14 September 2017

Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition

1 reference

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14 September 2017

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

1 reference

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14 September 2017

The extracellular matrix as a cell survival factor

1 reference

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14 September 2017

Overcoming anoikis--pathways to anchorage-independent growth in cancer.

1 reference

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2 September 2018

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2 September 2018

Tumor cell invasiveness correlates with changes in integrin expression and localization

1 reference

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2 September 2018

The morphological and molecular features of the epithelial-to-mesenchymal transition

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21 January 2018

Reversible transition towards a fibroblastic phenotype in a rat carcinoma cell line

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The characterization of alpha5-integrin expression on tubular epithelium during renal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24201814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDDIS.2013.442

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24201814%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

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29 February 2020

1 reference

Europe PubMed Central

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29 February 2020

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