(Q37357487)

English

The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic.

scientific article published on 23 July 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

prostaglandin E2

1 reference

based on heuristic

inferred from title

sexual dimorphism

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Costantino Iadecola

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

Alexander Kunz

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Munehisa Shimamura

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Ping Zhou

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Josef Anrather

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

language of work or name

1 reference

based on heuristic

inferred from title

publication date

23 July 2008

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Journal of Cerebral Blood Flow & Metabolism

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

29

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

66-72

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

How can we improve the pre-clinical development of drugs for stroke?

1 reference

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6 September 2017

Role of COX-2 in inflammatory and degenerative brain diseases.

1 reference

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6 September 2017

Established treatments for acute ischaemic stroke

1 reference

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6 September 2017

Bench to bedside: the quest for quality in experimental stroke research

1 reference

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6 September 2017

1,026 experimental treatments in acute stroke

1 reference

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6 September 2017

Adult or perinatal brain injury: does sex matter?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of gender

1 reference

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6 September 2017

Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

Recommendations for standards regarding preclinical neuroprotective and restorative drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

Reduction of focal cerebral ischemic damage by delayed treatment with nitric oxide donors

1 reference

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6 September 2017

Tissue plasminogen activator for acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

6 September 2017

Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

26 June 2018

Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

26 June 2018

The problem of assessing effective neuroprotection in experimental cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

26 June 2018

Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

26 June 2018

Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

26 June 2018

Neurovascular protection by ischemic tolerance: role of nitric oxide and reactive oxygen species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

The Paul Coverdell National Acute Stroke Registry: initial results from four prototypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

Inducible nitric oxide synthase contributes to gender differences in ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748840

2 September 2018

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

1 reference

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2 September 2018

Frequency of thrombolytic therapy in patients with acute ischemic stroke and the risk of in-hospital mortality: the German Stroke Registers Study Group

1 reference

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2 September 2018

Neuroprotection of cultured cortical neurons mediated by the cyclooxygenase-2 inhibitor APHS can be reversed by a prostanoid

1 reference

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2 September 2018

A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia.

1 reference

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2 September 2018

Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility.

1 reference

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2 September 2018

Polynitroxyl albumin reduces infarct size in transient focal cerebral ischemia in the rat: potential mechanisms studied by magnetic resonance imaging

1 reference

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2 September 2018

Development of tissue damage, inflammation and resolution following stroke: an immunohistochemical and quantitative planimetric study.

1 reference

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2 September 2018

Neuropathological endpoints in experimental stroke pharmacotherapy: the importance of both early and late evaluation.

1 reference

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2 September 2018

Cognitive deficits after focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection failure in stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoacetyl moiety as a potential surrogate for diacylhydrazine group of SC-51089, a potent PGE2 antagonist, and its analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18648380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/JCBFM.2008.88

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18648380%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

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