(Q37364099)

English

Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features

scientific article published on 05 January 2016

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19 August 2017

Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features (English)

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19 August 2017

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Joanna Collingwood

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Conceicao Bettencourt

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10 June 2020

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M Heidari

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D M Johnstone

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B Bassett

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R M Graham

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A C G Chua

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M J House

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H Houlden

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M Ryten

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D Trinder

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E A Milward

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Molecular Psychiatry

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10 June 2020

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10 June 2020

1599-1607

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10 June 2020

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5 January 2016

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Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Microarray Data Involving Small Changes.

1 reference

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6 September 2017

Neurodegeneration with Brain Iron Accumulation: Genetic Diversity and Pathophysiological Mechanisms

1 reference

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6 September 2017

Molecular regulators of nerve conduction - Lessons from inherited neuropathies and rodent genetic models

1 reference

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6 September 2017

Neurodegeneration with brain iron accumulation: diagnosis and management

1 reference

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6 September 2017

The role of iron in brain ageing and neurodegenerative disorders.

1 reference

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6 September 2017

Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

1 reference

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6 September 2017

PLA2G6-associated neurodegeneration (PLAN): further expansion of the clinical, radiological and mutation spectrum associated with infantile and atypical childhood-onset disease

1 reference

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6 September 2017

Glial cell ceruloplasmin and hepcidin differentially regulate iron efflux from brain microvascular endothelial cells

1 reference

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6 September 2017

Repeated mild traumatic brain injury results in long-term white-matter disruption.

1 reference

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6 September 2017

Role of myelin plasticity in oscillations and synchrony of neuronal activity

1 reference

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6 September 2017

Iron status in children with autism spectrum disorder

1 reference

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6 September 2017

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

1 reference

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6 September 2017

Iron dysregulation in movement disorders

1 reference

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6 September 2017

Iron sensing and signalling

1 reference

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6 September 2017

Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation

1 reference

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6 September 2017

Neuroimaging features of neurodegeneration with brain iron accumulation.

1 reference

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6 September 2017

Hemochromatosis-induced bipolar disorder: a case report

1 reference

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6 September 2017

Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration

1 reference

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6 September 2017

In silico QTL mapping of basal liver iron levels in inbred mouse strains

1 reference

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6 September 2017

Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism

1 reference

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6 September 2017

Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations

1 reference

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6 September 2017

Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations

1 reference

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6 September 2017

C2orf37 mutational spectrum in Woodhouse-Sakati syndrome patients.

1 reference

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6 September 2017

Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Fatty acid 2-Hydroxylation in mammalian sphingolipid biology

1 reference

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6 September 2017

AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology.

1 reference

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6 September 2017

Oligodendrocytes and myelination: the role of iron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Absence of 2-hydroxylated sphingolipids is compatible with normal neural development but causes late-onset axon and myelin sheath degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Non-classical hereditary hemochromatosis in Portugal: novel mutations identified in iron metabolism-related genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Nonheme-iron histochemistry for light and electron microscopy: a historical, theoretical and technical review

1 reference

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6 September 2017

LPA-mediated demyelination in ex vivo culture of dorsal root

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron

1 reference

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6 September 2017

A mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin

1 reference

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6 September 2017

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1 reference

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6 September 2017

Ceruloplasmin metabolism and function

1 reference

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6 September 2017

Adjusting for multiple testing--when and how?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

1 reference

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6 September 2017

Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

HFE gene knockout produces mouse model of hereditary hemochromatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

The ferritins: molecular properties, iron storage function and cellular regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

6 September 2017

Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

14 September 2017

Iron overload among a psychiatric outpatient population

1 reference

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28 September 2017

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.

1 reference

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26 June 2018

Transferrin is an essential factor for myelination

1 reference

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26 June 2018

Arachidonic acid inhibits myelin basic protein phosphorylation in cultured oligodendrocytes

1 reference

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26 June 2018

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1 reference

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2 September 2018

Adult neural precursor cells from the subventricular zone contribute significantly to oligodendrocyte regeneration and remyelination.

1 reference

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2 September 2018

MRI measures of corpus callosum iron and myelin in early Huntington's disease.

1 reference

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2 September 2018

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1 reference

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2 September 2018

Brain iron takes off: a new propeller protein links neurodegeneration with autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Brain transcriptome perturbations in the transferrin receptor 2 mutant mouse support the case for brain changes in iron loading disorders, including effects relating to long-term depression and long-term potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Mutations in the HFE, TFR2, and SLC40A1 genes in patients with hemochromatosis.

1 reference

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2 September 2018

Non-protein-bound iron and 4-hydroxynonenal protein adducts in classic autism

1 reference

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2 September 2018

Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Mutations in HFE and TFR2 genes in a Spanish patient with hemochromatosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Defective FA2H leads to a novel form of neurodegeneration with brain iron accumulation (NBIA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet

1 reference

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2 September 2018

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1 reference

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2 September 2018

Movement disorders in the Hfe knockout mouse

1 reference

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2 September 2018

Hereditary ferritinopathy: a novel mutation, its cellular pathology, and pathogenetic insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Effects of development and iron status on ceruloplasmin expression in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Severity of neurodegeneration correlates with compromise of iron metabolism in mice with iron regulatory protein deficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

The effect of age on the non-haemin iron in the human brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078858

2 September 2018

Investigations on Pantothenic Acid and Its Related Compounds: IX. Biochemical Studies (4).* Separation and Substrate Specificity of Pantothenate Kinase and Phosphopantothenoylcysteine Synthetase**

1 reference

https://pubmed.ncbi.nlm.nih.gov/26728570

12 December 2020

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Proceedings of the third joint symposium on neuroacanthocytosis and neurodegeneration with brain iron accumulation: from benchside to bedside

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https://pubmed.ncbi.nlm.nih.gov/26728570

12 December 2020

based on heuristic

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The Effect of Injections of Lysophosphatidyl Choline into White Matter of the Adult Mouse Spinal Cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/26728570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26728570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early manifestations of BPAN in a pediatric patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/26728570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic heterogeneity in Woodhouse-Sakati syndrome: two new families with a mutation in the C2orf37 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/26728570

12 December 2020

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10.1038/MP.2015.192

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Europe PubMed Central

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10 June 2020

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10 June 2020

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10 June 2020

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