(Q37365816)

20 August 2017

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title

Neuropeptidases and the metabolic inactivation of insect neuropeptides (English)

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20 August 2017

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3

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author name string

R Elwyn Isaac

series ordinal

1

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PubMed ID

19135055

20 August 2017

Nicholas D Bland

series ordinal

2

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20 August 2017

24 December 2008

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General and Comparative Endocrinology

20 August 2017

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20 August 2017

162

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20 August 2017

1

1 reference

20 August 2017

8-17

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GLP-1 based therapy for type 2 diabetes

20 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Allatostatins: a growing family of neuropeptides with structural and functional diversity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Identification and partial characterization of the enzyme of omega: one of five putative DPP IV genes in Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Using FlyAtlas to identify better Drosophila melanogaster models of human disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Mechanisms of initiation and termination of signalling by neuropeptide receptors: a comparison with the proteinase-activated receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Structure-activity studies with endogenous allatostatins from Periplaneta americana: expressed receptor compared with functional bioassay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Degradation of Dip-allatostatins by hemolymph from the cockroach, Diploptera punctata.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Inactivation of Dip-allatostatin 5 by membrane preparations from the cockroach Diploptera punctata.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Proteases for processing proneuropeptides into peptide neurotransmitters and hormones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Isolation of two differentially glycosylated forms of peptidyl-dipeptidase A (angiotensin converting enzyme) from pig brain: a re-evaluation of their role in neuropeptide metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Brain-specific aminopeptidase: from enkephalinase to protector against neurodegeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

A novel peptide-processing activity of insect peptidyl-dipeptidase A (angiotensin I-converting enzyme): the hydrolysis of lysyl-arginine and arginyl-arginine from the C-terminus of an insect prohormone peptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Proctolin degradation by membrane peptidases from nervous tissues of the desert locust (Schistocerca gregaria)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Neuropeptide-degrading endopeptidase activity of locust (Schistocerca gregaria) synaptic membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Angiotensin-converting enzyme as a target for the development of novel insect growth regulators.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Identification and localization of a neprilysin-like activity that degrades tachykinin-related peptides in the brain of the cockroach, Leucophaea maderae, and locust, Locusta migratoria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Inactivation of a tachykinin-related peptide: identification of four neuropeptide-degrading enzymes in neuronal membranes of insects from four different orders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Toward a role for angiotensin-converting enzyme in insects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Inactivation of neurotensin and neuromedin N by Zn metallopeptidases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

A cytosolic form of aminopeptidase P from Drosophila melanogaster: molecular cloning and characterization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Identification of an ACE-like peptidyl dipeptidase activity in the housefly, Musca domestica.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Metabolism of insect neuropeptides: properties of a membrane-bound endopeptidase from heads of Musca domestica.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Hydrolysis of insect neuropeptides by an angiotensin-converting enzyme from the housefly, Musca domestica.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

The endopeptidase activity and the activation by Cl- of angiotensin-converting enzyme is evolutionarily conserved: purification and properties of an an angiotensin-converting enzyme from the housefly, Musca domestica

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Jacques Benoit lecture: the neuroendocrine view of the angiotensin and apelin systems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

An endothelin-converting enzyme homologue in the locust, Locusta migratoria: functional activity, molecular cloning and tissue distribution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

High-affinity enkephalin-degrading peptidase in brain is increased after morphine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Proline-specific dipeptidyl peptidase from the blue blowfly Calliphora vicina hydrolyzes in vitro the ecdysiostatic peptide trypsin-modulating oostatic factor (Neb-TMOF).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

In vitro metabolism of an insect neuropeptide by neural membrane preparations from Lymantria dispar

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Characterization of a functionally expressed dipeptidyl aminopeptidase III from Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Purification, partial sequencing and characterization of an insect membrane dipeptidyl aminopeptidase that degrades the insect neuropeptide proctolin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Identification and characterization of two dipeptidyl-peptidase III isoforms in Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

7 January 2021

Cell-surface peptidases

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Endothelin-like immunoreactivity in midgut endocrine cells of the desert locust, Locusta migratoria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Expression of the endothelin-converting enzyme-1 isoforms in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Abundant distribution of locustatachykinin-like peptide in the nervous system and intestine of the cockroach Leucophaea maderae.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Isolation of five tachykinin-related peptides from the midgut of the cockroach Leucophaea maderae: existence of N-terminally extended isoforms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Hemolymph and tissue-bound peptidase-resistant analogs of the insect allatostatins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

An aminoisobutyric acid-containing analogue of the cockroach tachykinin-related peptide, LemTRP-1, with potent bioactivity and resistance to an insect angiotensin-converting enzyme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Enhanced in vivo activity of peptidase-resistant analogs of the insect kinin neuropeptide family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Insect myotropic peptides: differential distribution of locustatachykinin- and leucokinin-like immunoreactive neurons in the locust brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Neuropeptides in the nervous system of Drosophila and other insects: multiple roles as neuromodulators and neurohormones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Neuropeptides in interneurons of the insect brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Proline-specific dipeptidyl peptidase activity in the cockroach brain and intestine: partial characterization, distribution, and inactivation of tachykinin-related peptides.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Locust adipokinetic hormones: carrier-independent transport and differential inactivation at physiological concentrations during rest and flight

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Metabolism of proctolin, a pentapeptide neurotransmitter in insects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

MEROPS: the peptidase database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Endothelin-converting enzyme-1 degrades internalized somatostatin-14.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Immunocytochemical distribution of angiotensin I-converting enzyme-like immunoreactivity in the brain and testis of insects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Expression and functional characterization of a Drosophila neuropeptide precursor with homology to mammalian preprotachykinin A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Peptidyl dipeptidases (Ance and Acer) of Drosophila melanogaster: major differences in the substrate specificity of two homologs of human angiotensin I-converting enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Dipeptidyl aminopeptidase III of guinea-pig brain: specificity for short oligopeptide sequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Analogs of the insect myotropic peptide proctolin: Synthesis and structure-activity studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Metabolism of insect hypertrehalosemic hormone in Blaberus discoidalis cockroaches.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Structural basis of proline-specific exopeptidase activity as observed in human dipeptidyl peptidase-IV

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Biological activities of the allatostatin family of peptides in the cockroach, Diploptera punctata, and potential interactions with receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

The neprilysin family in health and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

The angiotensin-converting enzyme gene family: genomics and pharmacology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Are there neuropeptide-specific peptidases?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Extracellular peptidase activity tunes motor pattern modulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Proline-dependent structural and biological properties of peptides and proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

A new feature of angiotensin-converting enzyme in the brain: Hydrolysis of substance P

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

Furin: the prototype mammalian subtilisin-like proprotein-processing enzyme. Endoproteolytic cleavage at paired basic residues of proproteins of the eukaryotic secretory pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGCEN.2008.12.011

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YGCEN.2008.12.011

1 reference

20 August 2017

1 reference

PubMed ID

19135055