(Q37367625)

English

Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells

scientific article published on May 1997

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells (English)

1 reference

Europe PubMed Central

20 August 2017

author name string

H P Brezinschek

1

1 reference

Europe PubMed Central

20 August 2017

S J Foster

2

1 reference

Europe PubMed Central

20 August 2017

R I Brezinschek

3

1 reference

Europe PubMed Central

20 August 2017

T Dörner

4

1 reference

Europe PubMed Central

20 August 2017

R Domiati-Saad

5

1 reference

Europe PubMed Central

20 August 2017

P E Lipsky

6

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

1 May 1997

1 reference

Europe PubMed Central

20 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

20 August 2017

99

1 reference

Europe PubMed Central

20 August 2017

2488-2501

1 reference

Europe PubMed Central

20 August 2017

10

1 reference

Europe PubMed Central

20 August 2017

Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

A majority of Ig H chain cDNA of normal human adult blood lymphocytes resembles cDNA for fetal Ig and natural autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Molecular characterization of human Ig heavy chain DIR genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Staphylococcal protein A induces biased production of Ig by VH3-expressing B lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Evidence for the overexpression of the VH4-34 (VH4.21) Ig gene segment in the normal adult human peripheral blood B cell repertoire.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Ethnic differences of polymorphism of an immunoglobulin VH3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Somatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Organization of human immunoglobulin heavy chain diversity gene loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Human immunoglobulin heavy-chain variable region genes: organization, polymorphism, and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Most peripheral B cells in mice are ligand selected

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Relationship of the CD5 B cell to human tonsillar lymphocytes that express autoantibody-associated cross-reactive idiotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Immunoglobulin VH clan and family identity predicts variable domain structure and may influence antigen binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

VH-gene representation in autoantibodies reflects the normal human B-cell repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Identification and analysis of a novel human surface CD5- B lymphocyte subset producing natural antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Molecular approaches to the study of human B-cell and (auto)antibody repertoire generation and selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

6 September 2017

Development of the primary antibody repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

14 September 2017

Somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

14 September 2017

Positive and negative selection events during B lymphopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

14 September 2017

B-cell superantigens: implications for selection of the human antibody repertoire.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

14 September 2017

CD5 B cells, a fetal B cell lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

14 September 2017

B-1 cells: unique origins and functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

28 September 2017

In vitro analysis of the generation and propagation of memory B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

28 September 2017

Life and death in germinal centers (redux).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

28 September 2017

Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

28 September 2017

B-1a, B-1b and B-2 B cells display unique VHDJH repertoires formed at different stages of ontogeny and under different selection pressures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

28 September 2017

Representation of rearranged VH gene segments in the human adult antibody repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Comparable profiles of the immunoglobulin heavy chain complementarity determining region (CDR)-3 in CD5+ and CD5- human cord blood B lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Early restriction of the human antibody repertoire.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Unique V gene usage by B-Ly1 cell lines, and a discordance between isotype switch commitment and variable region hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Maintenance of B-cell memory by long-lived cells generated from proliferating precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Human immunoglobulin VH and VK repertoire revealed by in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

26 June 2018

The VDJ repertoire expressed in human preB cells reflects the selection of bona fide heavy chains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

B1 and B2 cells differ in their potential to switch immunoglobulin isotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

The majority of human tonsillar CD5+ B cells express somatically mutated V kappa 4 genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

High frequency of somatically mutated IgM molecules in the human adult blood B cell repertoire.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508090

2 September 2018

DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative activation requirements of human peripheral blood, spleen, and lymph node B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

At least five DH genes of human immunoglobulin heavy chains are encoded in 9-kilobase DNA fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell receptor-beta mRNA splicing during thymic maturation in vivo and in an inducible T cell clone in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral human CD5+ and CD5- B cells may express somatically mutated VH5- and VH6-encoded IgM receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cells are generated throughout life in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VH gene usage is multiple myeloma: complete absence of the VH4.21 (VH4-34) gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the expression of CD5 by human B cells and correlation with functional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9153293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119433

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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