(Q37376569)

English

The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera

scientific article published on December 1997

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera (English)

1 reference

Europe PubMed Central

20 August 2017

0 references

0 references

1 reference

based on heuristic

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author name string

P A Rufo

1

1 reference

Europe PubMed Central

20 August 2017

D Merlin

2

1 reference

Europe PubMed Central

20 August 2017

M Riegler

3

1 reference

Europe PubMed Central

20 August 2017

M H Ferguson-Maltzman

4

1 reference

Europe PubMed Central

20 August 2017

B L Dickinson

5

1 reference

Europe PubMed Central

20 August 2017

C Brugnara

6

1 reference

Europe PubMed Central

20 August 2017

S L Alper

7

1 reference

Europe PubMed Central

20 August 2017

W I Lencer

8

1 reference

Europe PubMed Central

20 August 2017

language of work or name

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publication date

1 December 1997

1 reference

Europe PubMed Central

20 August 2017

Journal of Clinical Investigation

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Europe PubMed Central

20 August 2017

100

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Europe PubMed Central

20 August 2017

3111-3120

1 reference

Europe PubMed Central

20 August 2017

12

1 reference

Europe PubMed Central

20 August 2017

The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Regulated Cl transport, K and Cl permeability, and exocytosis in T84 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Basolateral potassium channel in turtle colon. Evidence for single-file ion flow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Synergistic action of cyclic adenosine monophosphate- and calcium-mediated chloride secretion in a colonic epithelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Carbachol increases basolateral K+ conductance in T84 cells. Simultaneous measurements of cell [Ca] and gK explore calcium's role

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Cl- secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Mechanism of cholera toxin action on a polarized human intestinal epithelial cell line: role of vesicular traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Clotrimazole: a review of its antifungal activity and therapeutic efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

6 September 2017

Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

14 September 2017

Potassium channels in epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

14 September 2017

Barrier function of epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

14 September 2017

Modulation of Cl- secretion by benzimidazolones. II. Coordinate regulation of apical GCl and basolateral GK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

28 September 2017

Positive and negative regulation of chloride secretion in T84 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

28 September 2017

Apical recruitment of CFTR in T-84 cells is dependent on cAMP and microtubules but not Ca2+ or microfilaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

28 September 2017

Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

28 September 2017

Ca2+ and cAMP activate different K+ conductances in the human intestinal goblet cell line HT29-Cl.16E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

28 September 2017

Regulation of an inwardly rectifying K channel in the T84 epithelial cell line by calcium, nucleotides and kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

28 September 2017

Characteristics of two basolateral potassium channel populations in human colonic crypts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Ca2+ regulated K+ and non-selective cation channels in the basolateral membrane of rat colonic crypt base cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Cytochrome P-450 metabolites mediate extracellular Ca(2+)-induced inhibition of apical K+ channels in the TAL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Cyclic AMP and Ca2+ interactions affecting epithelial chloride secretion in human cultured colonic epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Inhibition of cAMP- and Ca-dependent Cl- secretion by phorbol esters: inhibition of basolateral K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

A new class of inhibitors of cAMP-mediated Cl- secretion in rabbit colon, acting by the reduction of cAMP-activated K+ conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

In vitro measurement of gastrointestinal tissue permeability using a new diffusion cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Rapid epithelial restitution of human and rabbit colonic mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Carbachol induces oscillations of membrane potassium conductance in a colonic cell line, T84.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Established intestinal cell lines as model systems for electrolyte transport studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Characterization of a membrane potassium ion conductance in intestinal secretory cells using whole cell patch-clamp and calcium ion-sensitive dye techniques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Carbachol induces K+, Cl-, and nonselective cation conductances in T84 cells: a perforated patch-clamp study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Clotrimazole treatment of chronic mucocutaneous candidiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

26 June 2018

Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

2 September 2018

Calcium-mediated agonists activate an inwardly rectified K+ channel in colonic secretory cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

2 September 2018

Structural analysis of a human intestinal epithelial cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

2 September 2018

Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

2 September 2018

Apical membrane chloride channels in a colonic cell line activated by secretory agonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508524

2 September 2018

The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The outwardly rectifying Cl? channel is not involved in cAMP-mediated Cl? secretion in HT-29 cells: evidence for a very-low-conductance Cl? channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-activated K+ transport in erythrocytes. Comparison of binding and transport inhibition by scorpion toxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dilatation of the basilar artery in response to selective activation of endothelin B receptors in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: the imidazole ring is not required for inhibitory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cAMP-regulated and 293B-inhibited K+ conductance of rat colonic crypt base cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor promotes rapid response to epithelial injury in rabbit duodenum in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical studies with oral clotrimazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clotrimazole: intermittent therapy in chronic mucocutaneous candidiasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral clotrimazole in the treatment of esophageal candidiasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ba2+ inhibition of VIP- and A23187-stimulated Cl- secretion by T84 cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9399958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119866

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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