(Q37379383)

20 August 2017

Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases (English)

1 reference

20 August 2017

R P Xiao

1

1 reference

20 August 2017

E D Tomhave

2

1 reference

20 August 2017

D J Wang

3

1 reference

20 August 2017

X Ji

4

1 reference

20 August 2017

M O Boluyt

5

1 reference

20 August 2017

H Cheng

6

1 reference

20 August 2017

E G Lakatta

7

1 reference

20 August 2017

W J Koch

8

1 reference

20 August 2017

language of work or name

English

0 references

publication date

1 March 1998

1 reference

Journal of Clinical Investigation

20 August 2017

1 reference

20 August 2017

101

1 reference

20 August 2017

1273-1282

1 reference

20 August 2017

6

1 reference

Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Reduced beta 1 receptor messenger RNA abundance in the failing human heart

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Age-associated changes in beta-adrenergic modulation on rat cardiac excitation-contraction coupling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

The functional importance of beta 1 and beta 2 adrenoceptors in the human heart

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Turning off the signal: desensitization of beta-adrenergic receptor function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Model systems for the study of seven-transmembrane-segment receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Deterioration of beta-adrenergic modulation of cardiovascular function with aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Modulation of adrenergic receptors and G-transduction proteins in failing human ventricular myocardium

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Cardiovascular regulatory mechanisms in advanced age.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Structure and mechanism of the G protein-coupled receptor kinases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Transgenic manipulation of beta-adrenergic receptor kinase modifies cardiac myocyte contraction to norepinephrine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Beta-adrenoceptor subtypes in young and old rat ventricular myocytes: a combined patch-clamp and binding study.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Age and gender influence muscle sympathetic nerve activity at rest in healthy humans.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Effects of exercise on myocardial adenylate cyclase and Gi alpha expression in senescence

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Alterations in the properties of β-adrenergic receptors of myocardial membranes in aging: Impairments in agonist—receptor interactions and guanine nucleotide regulation accompany diminished catecholamine-responsiveness of adenylated cyclase

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Isoproterenol Responsiveness and Myocardial -Adrenergic Receptors in Young and Old Rats

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Decreased receptor activation with age. Can it be explained by desensitization?

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Spare receptors for beta-adrenoceptor-mediated positive inotropic effects of catecholamines in the human heart

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Beta 2-adrenergic receptor actions in neonatal and adult rat ventricular myocytes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Upregulation of adrenergic beta receptor subtypes in the senescent rat heart

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508681

Diminished inotropic response of aged myocardium to catecholamines

2 September 2018

1 reference

12 December 2020

1 reference

12 December 2020

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure

1 reference

12 December 2020

Beta-adrenergic agonist-mediated desensitization in senescent rats

1 reference

12 December 2020

Electrophysiological characterization of cardiac β2-adrenoceptors in sheep Purkinje fibers

1 reference

12 December 2020

Contractile response of individual cardiac myocytes to norepinephrine declines with senescence

1 reference

12 December 2020

Increased messenger RNA level of the inhibitory G protein alpha subunit Gi alpha-2 in human end-stage heart failure

1 reference

12 December 2020

On the physiologic role of beta-2 adrenoceptors in the human heart: in vitro and in vivo studies

1 reference

12 December 2020

Forskolin activation of adenylate cyclase in rat myocardium with age: effects of guanine nucleotide analogs

1 reference

12 December 2020

Beta 1-adrenoceptor stimulation and beta 2-adrenoceptor stimulation differ in their effects on contraction, cytosolic Ca2+, and Ca2+ current in single rat ventricular cells

1 reference

12 December 2020

Forskolin binding sites and G-protein immunoreactivity in rat hearts during aging

1 reference

12 December 2020

Beta 2-adrenergic receptor-stimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation

1 reference

12 December 2020

1 reference

12 December 2020

Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes

1 reference

12 December 2020

Response of failing canine and human heart cells to beta 2-adrenergic stimulation

1 reference

12 December 2020

Activation of beta-adrenergic receptor kinase during myocardial ischemia

1 reference

12 December 2020

cAMP signaling mechanisms with aging in rats

1 reference

12 December 2020

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

1 reference

12 December 2020

Localized cAMP-dependent signaling mediates beta 2-adrenergic modulation of cardiac excitation-contraction coupling

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI1335

1 reference

20 August 2017

1 reference

20 August 2017

1 reference