(Q37387501)

English

A two-amino acid insertion in the Cys146- Cys167 loop of the alphaIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding

scientific article published on September 1998

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

A two-amino acid insertion in the Cys146- Cys167 loop of the alphaIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1 reference

based on heuristic

inferred from title

author name string

Honda S

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Tomiyama Y

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Shiraga M

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Tadokoro S

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Takamatsu J

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Saito H

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Kurata Y

7

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Matsuzawa Y

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

1 September 1998

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

102

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1183-1192

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function

1 reference

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Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia

1 reference

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A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

1 reference

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GPIIb-IIIa: the responsive integrin

1 reference

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6 September 2017

1 reference

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A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation

1 reference

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Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

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A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3

1 reference

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Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia

1 reference

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Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics

1 reference

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Molecular basis of CD36 deficiency. Evidence that a 478C-->T substitution (proline90-->serine) in CD36 cDNA accounts for CD36 deficiency

1 reference

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28 September 2017

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3.

1 reference

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28 September 2017

A novel regulatory epitope defined by a murine monoclonal antibody to the platelet GPIIb-IIIa complex (alpha IIb beta 3 integrin).

1 reference

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26 June 2018

Molecular requirements for assembly and function of a minimized human integrin alphaIIbbeta3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509101

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Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

1 reference

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A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509101

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Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

1 reference

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Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor

1 reference

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A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen.

1 reference

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Interchain and intrachain disulphide bonds in human platelet glycoprotein IIb. Localization of the epitopes for several monoclonal antibodies

1 reference

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Organization of the gene for platelet glycoprotein IIb.

1 reference

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The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit.

1 reference

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A discrete sequence in a platelet integrin is involved in ligand recognition

1 reference

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Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide

1 reference

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The Arg-Gly-Asp (RGD) recognition site of platelet glycoprotein IIb-IIIa on nonactivated platelets is accessible to high-affinity macromolecules

1 reference

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A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site.

1 reference

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26 June 2018

The amino-terminal one-third of alpha IIb defines the ligand recognition specificity of integrin alpha IIb beta 3.

1 reference

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1 reference

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Mutation of a ligand binding domain of beta 3 integrin. Integral role of oxygenated residues in alpha IIb beta 3 (GPIIb-IIIa) receptor function.

1 reference

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1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

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based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-binding properties of the platelet glycoprotein IIb ligand-interacting domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

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based on heuristic

inferred from PubMed ID database lookup

Activation of the fibrinogen binding site on platelets isolated from a patient with the Strasbourg I variant of Glanzmann's thrombasthenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of a marked reduction in the amount of GPIIb in most type II patients with Glanzmann's thrombasthenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

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based on heuristic

inferred from PubMed ID database lookup

Abnormal processing of the glycoprotein IIb transcript due to a nonsense mutation in exon 17 associated with Glanzmann's thrombasthenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affinity modulation of the platelet integrin alpha IIb beta 3 by alpha-chymotrypsin: a possible role for Na+/Ca2+ exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

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based on heuristic

inferred from PubMed ID database lookup

The anti-platelet and anti-thrombotic effects of FK633, a peptide-mimetic GPIIB/IIIA antagonist

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Glycoprotein IIb Leu214Pro mutation produces glanzmann thrombasthenia with both quantitative and qualitative abnormalities in GPIIb/IIIa

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of fibrinogen with its platelet receptor. Differential effects of alpha and gamma chain fibrinogen peptides on the glycoprotein IIb-IIIa complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9739052

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based on heuristic

inferred from PubMed ID database lookup

Platelet aggregation caused by dithiothreitol

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI3206

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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