(Q37393446)

English

Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor.

scientific article published on May 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19460614%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19460614%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

malignant hyperthermia

1 reference

based on heuristic

inferred from title

Takeshi Suetomi

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19460614%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Shigeki Kobayashi

1

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28 January 2020

Masafumi Yano

2

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28 January 2020

Makoto Ono

4

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28 January 2020

Hiroki Tateishi

5

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28 January 2020

Mamoru Mochizuki

6

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28 January 2020

Xiaojuan Xu

7

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28 January 2020

Hitoshi Uchinoumi

8

1 reference

Europe PubMed Central

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28 January 2020

Shinichi Okuda

9

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28 January 2020

Takeshi Yamamoto

10

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28 January 2020

Noritaka Koseki

11

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28 January 2020

Hiroyuki Kyushiki

12

1 reference

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28 January 2020

Noriaki Ikemoto

13

1 reference

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28 January 2020

Masunori Matsuzaki

14

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28 January 2020

language of work or name

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publication date

1 May 2009

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28 January 2020

Journal of the American College of Cardiology

1 reference

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28 January 2020

53

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28 January 2020

21

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28 January 2020

1993-2005

1 reference

Europe PubMed Central

PMC publication ID

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28 January 2020

Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

6 September 2017

Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

6 September 2017

Abnormal ryanodine receptor function in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

6 September 2017

Dantrolene inhibition of ryanodine receptor Ca2+ release channels. Molecular mechanism and isoform selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

28 September 2017

Malignant hyperthermia: excitation-contraction coupling, Ca2+ release channel, and cell Ca2+ regulation defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

28 September 2017

Probing a putative dantrolene-binding site on the cardiac ryanodine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

26 June 2018

The RyR2 central domain peptide DPc10 lowers the threshold for spontaneous Ca2+ release in permeabilized cardiomyocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

Correction of defective interdomain interaction within ryanodine receptor by antioxidant is a new therapeutic strategy against heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

Dantrolene stabilizes domain interactions within the ryanodine receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

Dantrolene: effects on abnormal intracellular Ca(2+) handling and inotropy in postinfarcted rat myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

Identification of a dantrolene-binding sequence on the skeletal muscle ryanodine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

Spectroscopic monitoring of local conformational changes during the intramolecular domain-domain interaction of the ryanodine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764410

2 September 2018

Effects of dantrolene sodium on intracellular Ca2(+)-handling in normal and Ca2(+)-overloaded cardiac muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19460614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postulated role of interdomain interaction within the ryanodine receptor in Ca(2+) channel regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19460614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dantrolene sodium improves the force-frequency relationship and beta-adregenic responsiveness in failing human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19460614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19460614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JACC.2009.01.065

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19460614%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19460614%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19460614%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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