(Q37394545)

English

Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition

scientific article published on 05 April 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

apoptotic process

0 references

author name string

Kristin Anselmi

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Donna B Stolz

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Michael Nalesnik

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Simon C Watkins

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Ravindra Kamath

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Chandrashekhar R Gandhi

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

5 April 2007

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Journal of Hepatology

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

47

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

103-113

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Therapeutic potential of Kupffer cells in prevention of liver metastases outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Endotoxin and Kupffer cell activation in alcoholic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Differentiation and function of Kupffer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Oxidative and alkylating damage in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Mutagenicity, toxicity and repair of DNA base damage induced by oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Oxidative damage to DNA: formation, measurement and biochemical features.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore

1 reference

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6 September 2017

Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Biochemical and cellular mechanisms of toxic liver injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Mechanisms of hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Cellular mechanisms for the repression of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Interactions between hepatic stellate cells and the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Cytokine receptors and signaling in hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Function and activation of NF-kappa B in the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

Immunosuppression in vitro by a metabolite of a human pathogenic fungus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

The chemistry and biology of the immunomodulating agent gliotoxin and related epipolythiodioxopiperazines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

6 September 2017

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

14 September 2017

2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

14 September 2017

Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

28 September 2017

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

28 September 2017

Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

28 September 2017

Activation of p38 mitogen-activated protein kinase and partial reactivation of the cell cycle by cis-4-methylsphingosine direct postmitotic neurons towards apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

NF-kappaB determines between apoptosis and proliferation in hepatocytes during liver regeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

Redox regulation of NF-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

Kupffer cells from CCl4-induced fibrotic livers stimulate proliferation of fat-storing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

The effect of gliotoxin upon macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

Two distinct pathways of platelet-activating factor-induced hydrolysis of phosphoinositides in primary cultures of rat Kupffer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2',7'-dichlorofluorescin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

26 June 2018

Mechanisms of endotoxin-induced NO, IL-6, and TNF-alpha production in activated rat hepatic stellate cells: role of p38 MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Sphinganine causes early activation of JNK and p38 MAPK and inhibition of AKT activation in HT-29 human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Superoxide-induced apoptosis of activated rat hepatic stellate cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Gliotoxin-mediated apoptosis of activated human hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Gadolinium chloride reverses dimethylnitrosamine (DMN)-induced rat liver fibrosis with increased matrix metalloproteinases (MMPs) of Kupffer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764960

2 September 2018

Identification of an agent in cultures of Aspergillus fumigatus displaying anti-phagocytic and immunomodulating activity in vitro

1 reference

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2 September 2018

Kupffer cells: Another player in liver tolerance induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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Cell population kinetics of Kupffer cells during the onset of fibrosis in rat liver by chronic carbon tetrachloride administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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inferred from PubMed ID database lookup

Inhibition of LPS-mediated activation in rat Kupffer cells by N-acetylcysteine occurs subsequent to NF-kappaB translocation and requires protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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An endothelin receptor antagonist TAK-044 ameliorates carbon tetrachloride-induced acute liver injury and portal hypertension in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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Expression of TNF-alpha and immunohistochemical distribution of hepatic macrophage surface markers in carbon tetrachloride-induced chronic liver injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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Kupffer cell inactivation delays repair in a rat model of reversible biliary obstruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17466404

12 December 2020

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Identifiers

10.1016/J.JHEP.2007.02.024

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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