(Q37396511)

English

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo

scientific article published on 14 July 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

photoreceptor protein

0 references

Samantha Roshani De Silva

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27416076%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Peter Charbel Issa

2

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Europe PubMed Central

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10 June 2020

Robert MacLaren

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27416076%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Mandeep S Singh

3

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10 June 2020

Daniel M Lipinski

4

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10 June 2020

Alona O Barnea-Cramer

5

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10 June 2020

Nathan J Walker

6

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10 June 2020

Alun R Barnard

7

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10 June 2020

Mark W Hankins

8

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10 June 2020

publication date

14 July 2016

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20 August 2017

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10 June 2020

23

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10 June 2020

11

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10 June 2020

767-774

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10 June 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5097463/fullTextXML

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Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice

1 reference

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Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.

1 reference

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1 reference

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6 September 2017

Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology

1 reference

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6 September 2017

Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo

1 reference

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6 September 2017

Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors

1 reference

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6 September 2017

Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina

1 reference

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6 September 2017

Three-year follow-up after unilateral subretinal delivery of adeno-associated virus in patients with Leber congenital Amaurosis type 2

1 reference

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6 September 2017

Retinal gene therapy with a large MYO7A cDNA using adeno-associated virus

1 reference

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6 September 2017

Clinical applications of retinal gene therapy.

1 reference

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6 September 2017

AAV2 gene therapy readministration in three adults with congenital blindness.

1 reference

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6 September 2017

Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration

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6 September 2017

Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years

1 reference

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6 September 2017

Gene therapy using self-complementary Y733F capsid mutant AAV2/8 restores vision in a model of early onset Leber congenital amaurosis

1 reference

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6 September 2017

Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey

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6 September 2017

Intravitreal injection of AAV2 transduces macaque inner retina

1 reference

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6 September 2017

Gene therapy in ophthalmology: validation on cultured retinal cells and explants from postmortem human eyes

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Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina

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6 September 2017

Vision 1 year after gene therapy for Leber's congenital amaurosis

1 reference

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6 September 2017

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

1 reference

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6 September 2017

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

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Effect of gene therapy on visual function in Leber's congenital amaurosis

1 reference

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Safety and efficacy of gene transfer for Leber's congenital amaurosis

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Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration

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Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

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10.1038/GT.2016.54

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Europe PubMed Central

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10 June 2020

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10 June 2020

PubMed publication ID

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Europe PubMed Central

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10 June 2020

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