(Q37397418)

20 August 2017

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title

A new perspective on the treatment of aromatic L-amino acid decarboxylase deficiency (English)

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aromatic L-amino acid decarboxylase deficiency

20 August 2017

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author name string

George F G Allen

series ordinal

1

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PubMed ID

19231266

20 August 2017

John M Land

series ordinal

2

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PubMed ID

19231266

20 August 2017

Simon J R Heales

series ordinal

3

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20 August 2017

27 January 2009

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Molecular Genetics and Metabolism

20 August 2017

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20 August 2017

97

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20 August 2017

1

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20 August 2017

6-14

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Trace amines: identification of a family of mammalian G protein-coupled receptors

20 August 2017

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Pig kidney dopa decarboxylase. Structure and function

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Aromatic L-amino acid decarboxylase: biological characterization and functional role.

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Decarboxylation of L-dopa by cultured mouse astrocytes

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Gene expression of aromatic L-amino acid decarboxylase in cultured rat glial cells

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Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme

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Intrarenal dopamine: a key signal in the interactive regulation of sodium metabolism

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Clinical and therapeutic observations in aromatic L-amino acid decarboxylase deficiency.

7 January 2021

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Development of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin.

7 January 2021

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Perturbed pattern of catecholamine-containing neurons in mutant Drosophila deficient in the enzyme dopa decarboxylase.

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The pediatric neurotransmitter disorders

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Inherited disorders affecting dopamine and serotonin: critical neurotransmitters derived from aromatic amino acids

7 January 2021

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The influence of L-dopa on methylation capacity in aromatic L-amino acid decarboxylase deficiency: biochemical findings in two patients

7 January 2021

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Levodopa-responsive aromatic L-amino acid decarboxylase deficiency

7 January 2021

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L-3,4-dihydroxyphenylalanine (levodopa) lowers central nervous system S-adenosylmethionine concentrations in humans

7 January 2021

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Demyelination and decreased S-adenosylmethionine in 5,10-methylenetetrahydrofolate reductase deficiency.

7 January 2021

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Medical management of levodopa-associated motor complications in patients with Parkinson's disease

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7 January 2021

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Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

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Aromatic L-amino acid decarboxylase modulation and Parkinson's disease.

7 January 2021

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Dopamine receptor pharmacology

7 January 2021

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A review of the receptor-binding and pharmacokinetic properties of dopamine agonists

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Prolactin and dopamine: what is the connection? A review article

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Aromatic L-amino acid decarboxylase deficiency: overview of clinical features and outcomes

7 January 2021

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Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a second family.

7 January 2021

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D1 dopamine receptor activity of anti-parkinsonian drugs

7 January 2021

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Valvular heart disease and the use of dopamine agonists for Parkinson's disease

7 January 2021

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Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

7 January 2021

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Regulation of striatal aromatic L-amino acid decarboxylase: effects of blockade or activation of dopamine receptors.

7 January 2021

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Regulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase by dopaminergic drugs.

7 January 2021

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Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors.

7 January 2021

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Tyrosine hydroxylase, aromatic L-amino acid decarboxylase and dopamine metabolism after chronic treatment with dopaminergic drugs.

7 January 2021

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Unusually mild phenotype of AADC deficiency in 2 siblings.

7 January 2021

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Modulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase after inhibiting monoamine oxidase-A.

7 January 2021

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Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells

7 January 2021

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The effects of administration of monoamine oxidase-B inhibitors on rat striatal neurone responses to dopamine

7 January 2021

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The effect of deprenyl, a selective monoamine oxidase B inhibitor, on sleep and mood in man.

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(-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.

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Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a new inborn error of neurotransmitter amine synthesis

7 January 2021

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Effect of pyridoxine deficiency on aromatic L-amino acid decarboxylase in adult rat brain.

7 January 2021

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Instability of the apo form of aromatic L-amino acid decarboxylase in vivo and in vitro: implications for the involvement of the flexible loop that covers the active site

7 January 2021

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Degradation of tyrosine aminotransferase (TAT) via the ubiquitin-proteasome pathway

7 January 2021

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B6-responsive disorders: a model of vitamin dependency

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Failure of vitamin B6 to reverse the L-dopa effect in patients on a dopa decarboxylase inhibitor

7 January 2021

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Evaluation of the holoenzyme content of aromatic L-amino acid decarboxylase in brain and liver tissues

7 January 2021

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What do we know about serotonin?

7 January 2021

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Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase

7 January 2021

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Pyridoxal 5'-phosphate may be curative in early-onset epileptic encephalopathy.

7 January 2021

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Aromatic L-amino acid decarboxylase deficiency with hyperdopaminuria. Clinical and laboratory findings in response to different therapies.

7 January 2021

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The mammalian pineal gland: known facts, unknown facets

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Changes in dopa decarboxylase mRNA but not tyrosine hydroxylase mRNA levels in rat brain following antipsychotic treatment

7 January 2021

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Regulation of aromatic L-amino acid decarboxylase by dopamine receptors in the rat brain

7 January 2021

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The emerging role of clozapine in the treatment of movement disorders

7 January 2021

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Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum

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Induction of aromatic-L-amino acid decarboxylase by decarboxylase inhibitors in idiopathic parkinsonism

7 January 2021

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NSD-1015 alters the gene expression of aromatic L-amino acid decarboxylase in rat PC12 pheochromocytoma cells

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Interaction of N-(DL-seryl)N′-(2,3,4-trihydroxybenzyl)-hydrazine with L-Dopa decarboxylase from pig kidney

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Restoration of the striatal dopamine synthesis for Parkinson's disease: viral vector-mediated enzyme replacement strategy.

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Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC.

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Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach

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Gene delivery using herpes simplex virus vectors

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Surface properties, more than size, limiting convective distribution of virus-sized particles and viruses in the central nervous system

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Potential of gene therapy for pediatric neurotransmitter diseases: lessons from Parkinson's disease

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Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development

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Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

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Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism

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7 January 2021

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19231266