(Q37399985)

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Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.

scientific article published on 24 February 2009

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Europe PubMed Central

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22 January 2020

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Europe PubMed Central

Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238500%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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Tetsushi Sadakata

1

1 reference

Europe PubMed Central

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22 January 2020

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Teiichi Furuichi

2

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Europe PubMed Central

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22 January 2020

publication date

24 February 2009

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238500%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238500%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

8

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Europe PubMed Central

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22 January 2020

3

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Europe PubMed Central

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22 January 2020

312-322

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238500%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Hypoplasia of Cerebellar Vermal Lobules VI and VII in Autism

1 reference

https://api.crossref.org/works/10.1007%2FS12311-009-0097-5

21 January 2018

Histoanatomic observations of the brain in early infantile autism

1 reference

https://api.crossref.org/works/10.1007%2FS12311-009-0097-5

21 January 2018

Practice parameter: screening and diagnosis of autism: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society

1 reference

https://api.crossref.org/works/10.1007%2FS12311-009-0097-5

21 January 2018

CAPS Acts at a Prefusion Step in Dense-Core Vesicle Exocytosis as a PIP2 Binding Protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+-dependent activator protein for secretion 1 is critical for constitutive and regulated exocytosis but not for loading of transmitters into dense core vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane association domains in Ca2+-dependent activator protein for secretion mediate plasma membrane and dense-core vesicle binding required for Ca2+-dependent exocytosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 controls proliferation of granular precursors as well as survival of mature granule neurons in the developing rat cerebellum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential patterns of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNA and protein levels in developing regions of rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Secretory Granule Phosphatidylinositol 4,5-Bisphosphate-interacting Proteins Using an Affinity Pulldown Strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the responses of Purkinje cells to neurotrophin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption in the inhibitory architecture of the cell minicolumn: implications for autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UNC-31 (CAPS) is required for dense-core vesicle but not synaptic vesicle exocytosis in Caenorhabditis elegans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pursuit eye movement deficits in autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sleep/wake rhythm in children with autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine hydroxylase immunoreactivity in cerebellar Purkinje cells of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-dependent activator protein for secretion is critical for the fusion of dense-core vesicles with the membrane in calf adrenal chromaffin cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in autism genetics: on the threshold of a new neurobiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is expressed in developing mouse cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+-dependent activator proteins of secretion promote vesicular monoamine uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Management of hyperactivity and other acting-out problems in patients with autism spectrum disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Homer family proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping Early Brain Development in Autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin induces tyrosine phosphorylation of the insulin receptor and SHC, and SHC/GRB2 association in cerebellum but not in forebrain cortex of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of Asperger syndrome and high-functioning autistic children on a Test of Motor Impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of phosphoinositide signaling in the control of insulin exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 is required for proper cerebellar development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins and cerebellar development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing variations in mouse CAPS2: differential expression and functional properties of splicing variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-4/5 (NT-4/5) and brain-derived neurotrophic factor (BDNF) act at later stages of cerebellar granule cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Climbing fiber development: do neurotrophins have a part to play?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAPS and syntaxin dock dense core vesicles to the plasma membrane in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel Ca2+-binding protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drosophila CAPS is an essential gene that regulates dense-core vesicle release and synaptic vesicle fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of age on elements of insulin-signaling pathway in central nervous system of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of dopamine-beta-hydroxylase-like immunoreactive fibers in the rat cerebellar cortex during ontogeny

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic UNC-31 (CAPS) is required to activate the G alpha(s) pathway of the Caenorhabditis elegans synaptic signaling network

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of tyrosine hydroxylase in cerebellar Purkinje neurons of the mutant tottering and leaner mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of austim: complex aetiology for a heterogeneous disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAPS1 regulates catecholamine loading of large dense-core vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacotherapy for hyperactivity in children with autism and other pervasive developmental disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 promotes cerebellar granule cell exit from the EGL.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebellar development transcriptome database (CDT-DB): Profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKA activation bypasses the requirement for UNC-31 in the docking of dense core vesicles from C. elegans neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynactin is required for bidirectional organelle transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/19238500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12311-009-0097-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238500%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238500%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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