(Q37402992)

20 August 2017

Importance of a hydrophobic residue in binding and catalysis by dihydrofolate reductase (English)

1 reference

20 August 2017

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R J Mayer

1

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20 August 2017

J T Chen

2

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20 August 2017

K Taira

3

1 reference

20 August 2017

C A Fierke

4

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20 August 2017

S J Benkovic

5

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20 August 2017

language of work or name

English

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publication date

1 October 1986

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Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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20 August 2017

83

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20 August 2017

20

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20 August 2017

7718-7720

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Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. II. Environment of bound NADPH and implications for catalysis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Active site of triosephosphate isomerase: in vitro mutagenesis and characterization of an altered enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Functional role of aspartic acid-27 in dihydrofolate reductase revealed by mutagenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Kinetics of ligand binding to dihydrofolate reductase: binary complex formation with NADPH and coenzyme analogues

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Kinetic mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Catalytic mechanism of the dihydrofolate reductase reaction as determined by pH studies.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Active-site mutants of beta-lactamase: use of an inactive double mutant to study requirements for catalysis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Modification of the active site of alkaline phosphatase by site-directed mutagenesis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Helix movements and the reconstruction of the haem pocket during the evolution of the cytochrome c family

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

Kinetics of substrate, coenzyme, and inhibitor binding to Escherichia coli dihydrofolate reductase.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

The pH-dependence of the binding of dihydrofolate and substrate analogues to dihydrofolate reductase from Escherichia coli.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=386792

The solubility of amino acids and two glycine peptides in aqueous ethanol and dioxane solutions. Establishment of a hydrophobicity scale

2 September 2018

1 reference

12 December 2020

Transient state kinetic analysis of the ATP-induced dissociation of the dynein-microtubule complex

1 reference

12 December 2020

Redesigning trypsin: alteration of substrate specificity

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12 December 2020

Site-specific mutagenesis of dihydrofolate reductase from Escherichia coli

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12 December 2020

Methotrexate-agarose in the purification of dihydrofolate reductase

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.83.20.7718

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20 August 2017

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20 August 2017

PubMed publication ID

3463995

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