(Q37408155)

20 August 2017

1 reference

title

Mitochondrial dynamics as a bridge between mitochondrial dysfunction and insulin resistance (English)

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20 August 2017

1 reference

1 reference

1 reference

Antonio Zorzano

1

1 reference

PubMed ID

19267277

20 August 2017

Marc Liesa

series ordinal

2

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PubMed ID

19267277

20 August 2017

Manuel Palacín

series ordinal

3

1 reference

20 August 2017

1 February 2009

1 reference

Archives of Physiology and Biochemistry

20 August 2017

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20 August 2017

115

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20 August 2017

1

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20 August 2017

1-12

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

20 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Coupling membranes as energy-transmitting cables. I. Filamentous mitochondria in fibroblasts and mitochondrial clusters in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial framework (reticulum mitochondriale) in rat diaphragm muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Dysregulation of HSG triggers vascular proliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PARL Leu262Val is not associated with fasting insulin levels in UK populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Upregulation of peroxisome proliferator-activated receptor gamma coactivator gene (PGC1A) during weight loss is related to insulin sensitivity but not to energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

hFis1, a novel component of the mammalian mitochondrial fission machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Analysis of functional domains of rat mitochondrial Fis1, the mitochondrial fission-stimulating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Fuel selection in human skeletal muscle in insulin resistance: a reexamination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Separate fusion of outer and inner mitochondrial membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial fusion intermediates revealed in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Could the low level of expression of the gene encoding skeletal muscle mitofusin-2 account for the metabolic inflexibility of obesity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Ras is involved in nerve-activity-dependent regulation of muscle genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Calcineurin controls nerve activity-dependent specification of slow skeletal muscle fibers but not muscle growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mitochondrial filaments and clusters as intracellular power-transmitting cables

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

A human dynamin-related protein controls the distribution of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PPARGC1A mRNA levels of in vitro differentiated human skeletal muscle cells are negatively associated with the plasma oleate concentrations of the donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

21 January 2018

Metabolic flexibility

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Regulation of muscle fiber type and running endurance by PPARdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The machinery of mitochondrial inheritance and behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PPARδ, but not PPARα, activates PGC-1α gene transcription in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450802676335

10.1080/13813450802676335

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19267277