(Q37412337)

20 August 2017

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title

Fibroblast growth factor 21: an overview from a clinical perspective (English)

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20 August 2017

Mikael Rydén

1

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20 August 2017

publication date

11 March 2009

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Cellular and Molecular Life Sciences

20 August 2017

published in

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20 August 2017

volume

66

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20 August 2017

issue

13

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20 August 2017

page(s)

2067-2073

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Identification of a novel FGF, FGF-21, preferentially expressed in the liver

20 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0003-9

Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0003-9

FGF21 N- and C-termini play different roles in receptor interaction and activation

21 January 2018

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12 December 2020

Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.

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12 December 2020

Fibroblast growth factor-21 as a therapeutic agent for metabolic diseases

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12 December 2020

FGF21 is an Akt-regulated myokine

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12 December 2020

PPARalpha is a key regulator of hepatic FGF21.

1 reference

12 December 2020

FGF23 is a hormone-regulating phosphate metabolism--unique biological characteristics of FGF23.

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12 December 2020

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

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12 December 2020

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

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12 December 2020

The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.

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12 December 2020

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

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12 December 2020

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

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12 December 2020

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

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12 December 2020

Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes

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12 December 2020

FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity

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12 December 2020

Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain

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12 December 2020

Plasma FGF-21 levels in type 2 diabetic patients with ketosis.

1 reference

12 December 2020

Leptin: pathophysiology and implications for therapy.

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12 December 2020

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

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12 December 2020

Molecular determinants of FGF-21 activity-synergy and cross-talk with PPARgamma signaling

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12 December 2020

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

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12 December 2020

Different roles of N- and C- termini in the functional activity of FGF21

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12 December 2020

Transcriptional profile of a myotube starvation model of atrophy.

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12 December 2020

Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.

1 reference

12 December 2020

Evolution of the Fgf and Fgfr gene families

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12 December 2020

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

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12 December 2020

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

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12 December 2020

FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho

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12 December 2020

Regulation of fibroblast growth factor-23 signaling by klotho

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12 December 2020

Fibroblast growth factor 21 corrects obesity in mice

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12 December 2020

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

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12 December 2020

FGF21: a missing link in the biology of fasting.

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12 December 2020

Serum levels of the adipokine FGF21 depend on renal function

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12 December 2020

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

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12 December 2020

Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.

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12 December 2020

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

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12 December 2020

Insulin resistance in type 2 diabetes: role of fatty acids

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12 December 2020

FGF-21 as a novel metabolic regulator

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12 December 2020

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

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12 December 2020

The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity

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12 December 2020

Plasma concentrations of fibroblast growth factors 19 and 21 in patients with anorexia nervosa.

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12 December 2020

Klotho converts canonical FGF receptor into a specific receptor for FGF23

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12 December 2020

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

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12 December 2020

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

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12 December 2020

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

1 reference

12 December 2020

10.1007/S00018-009-0003-9

Identifiers

DOI

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20 August 2017

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