(Q37440238)

English

Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke.

scientific article published on 16 September 2013

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scholarly article

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21 February 2020

Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke (English)

1 reference

Europe PubMed Central

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21 February 2020

Soluble epoxide hydrolase

0 references

2

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21 February 2020

author name string

Jafar Sadik B Shaik

1

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21 February 2020

Wenjin Li

3

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21 February 2020

Marie E Rose

4

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21 February 2020

Lesley M Foley

5

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21 February 2020

T Kevin Hitchens

6

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21 February 2020

Steven H Graham

7

1 reference

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21 February 2020

Sung Hee Hwang

8

1 reference

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21 February 2020

Bruce D Hammock

9

1 reference

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21 February 2020

Samuel M Poloyac

10

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21 February 2020

publication date

16 September 2013

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21 February 2020

American Journal of Physiology Heart and Circulatory Physiology

1 reference

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21 February 2020

305

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21 February 2020

11

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21 February 2020

H1605-13

1 reference

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21 February 2020

Epoxides and soluble epoxide hydrolase in cardiovascular physiology

1 reference

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23 August 2017

Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs

1 reference

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23 August 2017

Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Soluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single Agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition.

1 reference

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23 August 2017

Epoxyeicosanoid signaling in CNS function and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Update of the stroke therapy academic industry roundtable preclinical recommendations

1 reference

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23 August 2017

Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia

1 reference

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23 August 2017

The soluble epoxide hydrolase as a pharmaceutical target for hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Soluble epoxide hydrolase: a novel therapeutic target in stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Physiologic and pathophysiologic roles of lipid mediators in the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Action of epoxyeicosatrienoic acids on cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Role of astrocytes in cerebrovascular regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Cytochrome P450 in neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Perfusion imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Magnetic resonance imaging of perfusion using spin inversion of arterial water

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

23 August 2017

Free arachidonic acid and other lipids in the nervous system during early ischemia and after electroshock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

28 September 2017

An alternative method for the quantitation of neuronal damage after experimental middle cerebral artery occlusion in rats: analysis of behavioral deficit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

26 June 2018

Enhanced accumulation of free fatty acids in experimental focal cerebral ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

26 June 2018

Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

26 June 2018

Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

26 June 2018

Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

26 June 2018

Recovery of brain mitochondrial function in the rat after complete and incomplete cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

26 June 2018

Neuronal cyclooxygenase-2 activity and prostaglandins PGE2, PGD2, and PGF2 alpha exacerbate hypoxic neuronal injury in neuron-enriched primary culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

bcl-2 Antisense treatment prevents induction of tolerance to focal ischemia in the rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

Early perfusion after controlled cortical impact in rats: quantification by arterial spin-labeled MRI and the influence of spin-lattice relaxation time heterogeneity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

Free Fatty Acids in the Rat Brain in Moderate and Severe Hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

A semiautomated method for measuring brain infarct volume.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882464

2 September 2018

The role of arachidonic acid in vasogenic brain edema

1 reference

https://pubmed.ncbi.nlm.nih.gov/24043255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24043255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/24043255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.00471.2013

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24043255%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

release_ga4osebhtbgfdcngzsjsunuseq

1 reference

https://api.fatcat.wiki/v0/release/ga4osebhtbgfdcngzsjsunuseq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24043255%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

Europe PubMed Central

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21 February 2020

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