(Q37443917)

20 August 2017

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title

Barrett's oesophagus: an ideal model to study cancer genetics (English)

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20 August 2017

Massimiliano di Pietro

series ordinal

1

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PubMed ID

19365640

20 August 2017

Rebecca C Fitzgerald

series ordinal

2

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20 August 2017

14 April 2009

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20 August 2017

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20 August 2017

126

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20 August 2017

2

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20 August 2017

233-246

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https://scigraph.springernature.com/pub.10.1007/s00439-009-0665-2

20 August 2017

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cites work

Adenocarcinoma complicating columnar epithelium-lined (Barrett's) esophagus

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00439-009-0665-2

The columnar-lined esophagus, intestinal metaplasia, and Norman Barrett

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00439-009-0665-2

Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma

21 January 2018

1 reference

12 December 2020

Retinoic acid-induced glandular differentiation of the oesophagus.

1 reference

12 December 2020

Acid suppression and adenocarcinoma of the esophagus: cause or cure?

1 reference

12 December 2020

Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia.

1 reference

12 December 2020

Abdominal obesity and body mass index as risk factors for Barrett's esophagus

1 reference

12 December 2020

The hitch-hiking effect of a favourable gene

1 reference

12 December 2020

The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence

1 reference

12 December 2020

Is there publication bias in the reporting of cancer risk in Barrett's esophagus?

1 reference

12 December 2020

Reactive oxygen species: are they involved in the pathogenesis of GERD, Barrett's esophagus, and the latter's progression toward esophageal cancer?

1 reference

12 December 2020

Impaired transforming growth factor beta signalling in Barrett's carcinogenesis due to frequent SMAD4 inactivation

1 reference

12 December 2020

The role of Cdx genes in the mammalian gut.

1 reference

12 December 2020

Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure

1 reference

12 December 2020

Silencing of MGMT expression by promoter hypermethylation in the metaplasia-dysplasia-carcinoma sequence of Barrett's esophagus

1 reference

12 December 2020

Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus

1 reference

12 December 2020

Consortium approach to identifying genes for Barrett's esophagus and esophageal adenocarcinoma

1 reference

12 December 2020

Esophageal acid exposure at pH < or = 2 is more common in Barrett's esophagus patients and is associated with oxidative stress

1 reference

12 December 2020

Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells.

1 reference

12 December 2020

Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation.

1 reference

12 December 2020

Alterations in Barrett's-related adenocarcinomas: a proteomic approach

1 reference

12 December 2020

Increased expression of the cyclin D1 gene in Barrett's esophagus.

1 reference

12 December 2020

Systematic review: the application of molecular pathogenesis to prevention and treatment of oesophageal adenocarcinoma

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12 December 2020

Cyclin A Immunocytology as a Risk Stratification Tool for Barrett's Esophagus Surveillance

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12 December 2020

Intratumoral genetic heterogeneity in Barrett adenocarcinoma

1 reference

12 December 2020

Stepwise radical endoscopic resection of the complete Barrett's esophagus with early neoplasia successfully eradicates pre-existing genetic abnormalities

1 reference

12 December 2020

Cytostatic drug treatment causes seeding of gene promoter methylation

1 reference

12 December 2020

TP53 and progression from Barrett's metaplasia to oesophageal adenocarcinoma in a UK population cohort

1 reference

12 December 2020

CDX1 is an important molecular mediator of Barrett's metaplasia

1 reference

12 December 2020

Familial Barrett's esophagus associated with adenocarcinoma

1 reference

12 December 2020

Cyclin D1 polymorphism (G870A) and risk for esophageal adenocarcinoma

1 reference

12 December 2020

Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells

1 reference

12 December 2020

Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosa

1 reference

12 December 2020

Genetic polymorphisms of microsomal epoxide hydroxylase and glutathione S-transferases M1, T1 and P1, interactions with smoking, and risk for esophageal (Barrett) adenocarcinoma.

1 reference

12 December 2020

NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma

1 reference

12 December 2020

Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation

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12 December 2020

Matrix metalloproteinases, angiogenesis, and cancer: commentary re: A. C. Lockhart et al., Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor. Clin. Cancer Res., 9: 00-00, 2003.

1 reference

12 December 2020

Relevance of the detection of intestinal metaplasia in non-dysplastic columnar-lined oesophagus

1 reference

12 December 2020

Deoxycholic acid at neutral and acid pH, is genotoxic to oesophageal cells through the induction of ROS: The potential role of anti-oxidants in Barrett's oesophagus

1 reference

12 December 2020

p53 mutations in Barrett's adenocarcinoma and high-grade dysplasia

1 reference

12 December 2020

Chromosomal rearrangements in Barrett's esophagus. A premalignant lesion of esophageal adenocarcinoma

1 reference

12 December 2020

Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma.

1 reference

12 December 2020

Met expression is an independent prognostic risk factor in patients with oesophageal adenocarcinoma

1 reference

12 December 2020

Genetic polymorphisms of XRCC1 and risk of the esophageal cancer

1 reference

12 December 2020

Polymorphisms in DNA repair genes in the molecular pathogenesis of esophageal (Barrett) adenocarcinoma

1 reference

12 December 2020

Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma

1 reference

12 December 2020

Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus

1 reference

12 December 2020

Biomarkers of esophageal adenocarcinoma and Barrett's esophagus

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12 December 2020

p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium

1 reference

12 December 2020

Dilated intercellular spaces: a morphological feature of acid reflux--damaged human esophageal epithelium

1 reference

12 December 2020

A comparative analysis by SAGE of gene expression profiles of Barrett's esophagus, normal squamous esophagus, and gastric cardia

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12 December 2020

Is intestinal metaplasia a necessary precursor lesion for adenocarcinomas of the distal esophagus, gastroesophageal junction and gastric cardia?

1 reference

12 December 2020

Acid and bile salts induce DNA damage in human oesophageal cell lines

1 reference

12 December 2020

Helicobacter pylori infection and the risk of Barrett's oesophagus: a community-based study

1 reference

12 December 2020

Familial clustering of reflux symptoms

1 reference

12 December 2020

XRCC1 and XPD polymorphisms and esophageal adenocarcinoma risk.

1 reference

12 December 2020

Role of nitric oxide in carcinogenesis and tumour progression

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12 December 2020

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12 December 2020

Clonal expansion and loss of heterozygosity at chromosomes 9p and 17p in premalignant esophageal (Barrett's) tissue

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12 December 2020

Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK2 receptor

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12 December 2020

Activators and target genes of Rel/NF-kappaB transcription factors

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12 December 2020

Dedifferentiation precedes invasion in the progression from Barrett's metaplasia to esophageal adenocarcinoma

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12 December 2020

Identification of Barrett's esophagus in relatives by endoscopic screening

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12 December 2020

Angiogenic switch in Barrett's adenocarcinoma: the role of vascular endothelial growth factor

1 reference

12 December 2020

Hypermethylation of tumor suppressor genes (p16INK4A, p14ARF and APC) in adenocarcinomas of the upper gastrointestinal tract

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12 December 2020

Histopathology of Barrett's esophagus after ablation and endoscopic mucosal resection therapy

1 reference

12 December 2020

Progressive silencing of p14ARF in oesophageal adenocarcinoma

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12 December 2020

Epidemiologic risk factors for Barrett's esophagus and associated adenocarcinoma

1 reference

12 December 2020

Obesity prevalence from a European perspective: a systematic review

1 reference

12 December 2020

Principles of tumor suppression

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12 December 2020

Genetics of gastroesophageal cancer: paradigms, paradoxes, and prognostic utility.

1 reference

12 December 2020

Evolution of neoplastic cell lineages in Barrett oesophagus

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12 December 2020

Sonic hedgehog is essential to foregut development

1 reference

12 December 2020

Malignant degeneration of Barrett's esophagus: the role of the Ki-67 proliferation fraction, expression of E-cadherin and p53

1 reference

12 December 2020

Gastric acid suppression and risk of oesophageal and gastric adenocarcinoma: a nested case control study in the UK

1 reference

12 December 2020

Selectively advantageous mutations and hitchhikers in neoplasms: p16 lesions are selected in Barrett's esophagus

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12 December 2020

COX-2 CA-haplotype is a risk factor for the development of esophageal adenocarcinoma

1 reference

12 December 2020

Microsatellite instability in esophageal adenocarcinoma.

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12 December 2020

Extent of high-grade dysplasia in Barrett's esophagus correlates with risk of adenocarcinoma

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12 December 2020

The prognostic impact of O6-Methylguanine-DNA Methyltransferase (MGMT) promotor hypermethylation in esophageal adenocarcinoma.

1 reference

12 December 2020

Familial Barrett esophagus and adenocarcinoma of the gastroesophageal junction

1 reference

12 December 2020

Anti-p53 antibodies in patients with Barrett's esophagus or esophageal carcinoma can predate cancer diagnosis.

1 reference

12 December 2020

Persistent clonal areas and clonal expansion in Barrett's esophagus

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12 December 2020

FGF signal transduction and the regulation of Cdx gene expression.

1 reference

12 December 2020

COX2 expression, angiogenesis, proliferation and survival in Barrett's cancer

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12 December 2020

Recruitment of DNA methyltransferase I to DNA repair sites

1 reference

12 December 2020

Prevalence and characteristics of Barrett esophagus in patients with adenocarcinoma of the esophagus or esophagogastric junction

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12 December 2020

Predictors of progression to cancer in Barrett's esophagus: baseline histology and flow cytometry identify low- and high-risk patient subsets.

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12 December 2020

Cancer epigenomics: DNA methylomes and histone-modification maps

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12 December 2020

CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium

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12 December 2020

Interaction of Wnt and caudal-related genes in zebrafish posterior body formation

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12 December 2020

Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture

1 reference

12 December 2020

Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells

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12 December 2020

Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis

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12 December 2020

Polymorphisms of glutathione S-transferase M1, T1 and P1 in patients with reflux esophagitis and Barrett's esophagus

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12 December 2020

Epidemiology of gastro-oesophageal reflux disease: a systematic review

1 reference

12 December 2020

Central adiposity and risk of Barrett's esophagus

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12 December 2020

Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma

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12 December 2020

Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus

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12 December 2020

Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes

1 reference

12 December 2020

Chromosomal numerical aberrations are frequent in oesophageal and gastric adenocarcinomas: a study using in-situ hybridization

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12 December 2020

Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus

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12 December 2020

Surface expression of minichromosome maintenance proteins provides a novel method for detecting patients at risk for developing adenocarcinoma in Barrett's esophagus

1 reference

12 December 2020

DNA damage levels are raised in Barrett's oesophageal mucosa relative to the squamous epithelium of the oesophagus.

1 reference

12 December 2020

Familial gastroesophageal reflux and development of Barrett's esophagus

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12 December 2020

Stem cells of the oesophageal epithelium

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12 December 2020

Overexpression of TGF-beta1 in esophageal (Barrett's) adenocarcinoma is associated with advanced stage of disease and poor prognosis

1 reference

12 December 2020

Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery

1 reference

12 December 2020

Neoplastic risk assessment in Barrett’s esophagus: how far have we come?

1 reference

12 December 2020

Role of endoscopy in the management of GERD.

1 reference

12 December 2020

Wnt signaling in the intestinal epithelium: from endoderm to cancer

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12 December 2020

Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps

1 reference

12 December 2020

Novel mechanism of nitrosative stress from dietary nitrate with relevance to gastro-oesophageal junction cancers

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12 December 2020

Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention

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12 December 2020

Developmental changes in the oesophageal epithelium in man.

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12 December 2020

Ageing or cancer: a review on the role of caretakers and gatekeepers

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12 December 2020

Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

1 reference

12 December 2020

Role of Sonic hedgehog in the development of the trachea and oesophagus

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12 December 2020

Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma

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12 December 2020

Leptin and the risk of Barrett's oesophagus.

1 reference

12 December 2020

Interphase cytogenetics of esophageal adenocarcinoma and precursor lesions

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12 December 2020

Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors

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12 December 2020

Acid, bile, and CDX: the ABCs of making Barrett's metaplasia

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12 December 2020

Nitrate and nitrosative chemistry within Barrett's oesophagus during acid reflux

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12 December 2020

Met receptor signaling: a key effector in esophageal adenocarcinoma

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12 December 2020

Serum selenium levels in relation to markers of neoplastic progression among persons with Barrett's esophagus.

1 reference

12 December 2020

Incipient angiogenesis in Barrett's epithelium and lymphangiogenesis in Barrett's adenocarcinoma

1 reference

12 December 2020

Prevalence of Barrett's esophagus in the general population: an endoscopic study

1 reference

12 December 2020

Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium

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12 December 2020

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

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12 December 2020

Utility of biomarkers in prediction of response to ablative therapy in Barrett's esophagus

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12 December 2020

Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus

1 reference

12 December 2020

Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma

1 reference

12 December 2020

A population-based association study of SNPs of GSTP1, MnSOD, GPX2 and Barrett's esophagus and esophageal adenocarcinoma.

1 reference

12 December 2020

Preferred location for the development of esophageal adenocarcinoma within a segment of intestinal metaplasia

1 reference

12 December 2020

New British Society of Gastroenterology (BSG) guidelines for the diagnosis and management of Barrett's oesophagus

1 reference

12 December 2020

Oxidative stress has a role in malignant transformation in Barrett's oesophagus

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12 December 2020

Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction.

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12 December 2020

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

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12 December 2020

Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age.

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12 December 2020

Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis.

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12 December 2020

Cross-talks between cyclooxygenase-2 and tumor suppressor protein p53: Balancing life and death during inflammatory stress and carcinogenesis

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12 December 2020

Adenocarcinoma in the columnar epithelial lined lower (Barrett) oesophagus

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12 December 2020

Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus

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12 December 2020

Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma

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12 December 2020

The incidence of esophageal cancer and high-grade dysplasia in Barrett's esophagus: a systematic review and meta-analysis

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12 December 2020

Demographic and phenotypic features of 70 families segregating Barrett's oesophagus and oesophageal adenocarcinoma

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12 December 2020

Nitric oxide and acid induce double-strand DNA breaks in Barrett's esophagus carcinogenesis via distinct mechanisms

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12 December 2020

Expression analysis of Barrett's esophagus-associated high-grade dysplasia in laser capture microdissected archival tissue

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12 December 2020

Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinoma

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12 December 2020

Familial aggregation of Barrett's oesophagus, oesophageal adenocarcinoma, and oesophagogastric junctional adenocarcinoma in Caucasian adults

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12 December 2020

Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus

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12 December 2020

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

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12 December 2020

Multifocal heterogeneity in villin and Ep-CAM expression in Barrett's esophagus.

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12 December 2020

COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma

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12 December 2020

Defective mismatch-repair as a minor tumorigenic pathway in Barrett esophagus-associated adenocarcinoma

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12 December 2020

Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk

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12 December 2020

GERD is associated with shortened telomeres in the squamous epithelium of the distal esophagus.

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12 December 2020

Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Gene Polymorphisms and Risk of Reflux Esophagitis, Barrett's Esophagus, and Esophageal Adenocarcinoma

1 reference

12 December 2020

Temporal trends (1973-1997) in survival of patients with esophageal adenocarcinoma in the United States: a glimmer of hope?

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12 December 2020

Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence

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12 December 2020

In vivo and in vitro evidence for transforming growth factor-beta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma.

1 reference

12 December 2020

Familial aggregation of gastroesophageal reflux in patients with Barrett's esophagus and esophageal adenocarcinoma

1 reference

12 December 2020

Review article: prevalence of Barrett's oesophagus and metaplasia at the gastro-oesophageal junction

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12 December 2020

Chromosomal instability in Barrett's esophagus is related to telomere shortening.

1 reference

12 December 2020

Genetic influences in gastro-oesophageal reflux disease: a twin study

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12 December 2020

Replicative aging, telomeres, and oxidative stress

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12 December 2020

Development of the human gastrointestinal tract: twenty years of progress

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12 December 2020

Cyclooxygenase-2 expression in esophageal epithelium before and after photodynamic therapy for Barrett's esophagus with high-grade dysplasia or intramucosal carcinoma

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12 December 2020

BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway.

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12 December 2020

Long-term nonsurgical management of Barrett's esophagus with high-grade dysplasia

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12 December 2020

EGFR and HER-2 antagonists in breast cancer.

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12 December 2020

Endoscopic therapy for Barrett's oesophagus

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12 December 2020

Role of acid and duodenogastroesophageal reflux in gastroesophageal reflux disease.

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12 December 2020

Cardiac rather than intestinal-type background in endoscopic resection specimens of minute Barrett adenocarcinoma

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12 December 2020

LOH at the sites of the DCC, APC, and TP53 tumor suppressor genes occurs in Barrett's metaplasia and dysplasia adjacent to adenocarcinoma of the esophagus.

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12 December 2020

Prospective study of cyclin D1 overexpression in Barrett's esophagus: association with increased risk of adenocarcinoma.

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12 December 2020

Gastroesophageal reflux disease in monozygotic and dizygotic twins

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12 December 2020

10.1007/S00439-009-0665-2

Identifiers

DOI

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20 August 2017

1 reference

PubMed ID

19365640