(Q37462415)

20 August 2017

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title

Antizyme and antizyme inhibitor, a regulatory tango (English)

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20 August 2017

Chaim Kahana

1

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20 August 2017

publication date

28 April 2009

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Cellular and Molecular Life Sciences

20 August 2017

published in

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20 August 2017

volume

66

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20 August 2017

issue

15

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20 August 2017

page(s)

2479-2488

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The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Feedback repression of polyamine transport is mediated by antizyme in mammalian tissue-culture cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

A macromolecular inhibitor of the antizyme to ornithine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Overproduction of stable ornithine decarboxylase and antizyme in the difluoromethylornithine-resistant cell line DH23b

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Antizyme modifications affecting polyamine homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Osmotic stress induces variation in cellular levels of ornithine decarboxylase-antizyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

cis-recognition and degradation of ornithine decarboxylase subunits in reticulocyte lysate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Degradation of ornithine decarboxylase: exposure of the C-terminal target by a polyamine-inducible inhibitory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Distinct domains of antizyme required for binding and proteolysis of ornithine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Forced expression of antizyme abolishes ornithine decarboxylase activity, suppresses cellular levels of polyamines and inhibits cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Properties and fluctuations in vivo of rat liver antizyme inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0033-3

Antizyme and antizyme inhibitor activities influence cellular responses to polyamine analogs.

21 January 2018

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12 December 2020

Regulation of cellular polyamines by antizyme

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12 December 2020

Role of polyamines and their antimetabolites in clinical medicine

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12 December 2020

The nucleic acid-binding zinc finger protein of potato virus M is translated by internal initiation as well as by ribosomal frameshifting involving a shifty stop codon and a novel mechanism of P-site slippage

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12 December 2020

Reduction of ornithine decarboxylase antizyme (ODC-Az) level in the 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model

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12 December 2020

Structural elements of antizymes 1 and 2 are required for proteasomal degradation of ornithine decarboxylase

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12 December 2020

Characterization of sequences involved in mediating degradation of ornithine decarboxylase in cells and in reticulocyte lysate

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12 December 2020

Prevention of rapid intracellular degradation of ODC by a carboxyl-terminal truncation

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12 December 2020

The mechanisms of ornithine decarboxylase deregulation in c-Ha-ras oncogene-transformed NIH 3T3 cells.

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12 December 2020

Recoding: reprogrammed genetic decoding

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12 December 2020

Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis.

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12 December 2020

Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases

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12 December 2020

Yeast antizyme mediates degradation of yeast ornithine decarboxylase by yeast but not by mammalian proteasome: new insights on yeast antizyme

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12 December 2020

Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining repair of DNA double-strand breaks in human oral cancer cells

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12 December 2020

Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation

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12 December 2020

Purification and characterization of antizyme inhibitor of ornithine decarboxylase from rat liver

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12 December 2020

ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1.

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12 December 2020

Isolation of cloned cDNA encoding mammalian ornithine decarboxylase

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12 December 2020

Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme

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12 December 2020

Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase

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12 December 2020

A newly discovered function for RNase L in regulating translation termination

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12 December 2020

Induction of ornithine decarboxylase by 12-O-tetradecanoylphorbol 13-acetate in hamster fibroblasts. Relationship between levels of enzyme activity, immunoreactive protein, and RNA during the induction process.

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12 December 2020

Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function

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12 December 2020

Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity

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12 December 2020

Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures

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12 December 2020

Mitochondrial localization of antizyme is determined by context-dependent alternative utilization of two AUG initiation codons

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12 December 2020

Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cells

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12 December 2020

Polyamines and neoplastic growth

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12 December 2020

Antizyme inhibitor is rapidly induced in growth-stimulated mouse fibroblasts and releases ornithine decarboxylase from antizyme suppression

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12 December 2020

Identification and characterization of testis specific ornithine decarboxylase antizyme (OAZ-t) gene: expression in haploid germ cells and polyamine-induced frameshifting

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12 December 2020

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy

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12 December 2020

Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

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12 December 2020

A unified pathway for the degradation of ornithine decarboxylase in reticulocyte lysate requires interaction with the polyamine-induced protein, ornithine decarboxylase antizyme

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12 December 2020

A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs).

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12 December 2020

Anti-tumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation.

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12 December 2020

Role of ornithine decarboxylase antizyme inhibitor in vivo

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12 December 2020

Expression of antizyme inhibitor 2 in male haploid germinal cells suggests a role in spermiogenesis

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12 December 2020

High-resolution array comparative genomic hybridization of chromosome arm 8q: evaluation of genetic progression markers for prostate cancer.

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12 December 2020

Intersubunit location of the active site of mammalian ornithine decarboxylase as determined by hybridization of site-directed mutants

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12 December 2020

Cell culture analysis of the regulatory frameshift event required for the expression of mammalian antizymes

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12 December 2020

Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction

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12 December 2020

Antizyme2 is a negative regulator of ornithine decarboxylase and polyamine transport

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12 December 2020

A second mammalian antizyme: conservation of programmed ribosomal frameshifting

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12 December 2020

Degradation of antizyme inhibitor, an ornithine decarboxylase homologous protein, is ubiquitin-dependent and is inhibited by antizyme

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12 December 2020

Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting

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12 December 2020

Identification of differentially expressed genes in normal and tumor human gastric tissue.

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12 December 2020

Rearrangement between ornithine decarboxylase and the switch region of the gamma 1 immunoglobulin gene in alpha-difluoromethylornithine resistant mouse myeloma cells

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12 December 2020

Antizyme, a mediator of ubiquitin-independent proteasomal degradation and its inhibitor localize to centrosomes and modulate centriole amplification

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12 December 2020

Ornithine decarboxylase as a biologic marker in familial colonic polyposis

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12 December 2020

Ornithine decarboxylase activity is critical for cell transformation

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12 December 2020

Polyamine transport by mammalian cells and mitochondria: role of antizyme and glycosaminoglycans

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12 December 2020

Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis.

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12 December 2020

Antizyme, a mediator of ubiquitin-independent proteasomal degradation

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12 December 2020

Degradation of ornithine decarboxylase in Saccharomyces cerevisiae is ubiquitin independent

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12 December 2020

Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3

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12 December 2020

P-site tRNA is a crucial initiator of ribosomal frameshifting.

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12 December 2020

Antizyme protects against abnormal accumulation and toxicity of polyamines in ornithine decarboxylase-overproducing cells

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12 December 2020

Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression

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12 December 2020

Programmed frameshifting in the synthesis of mammalian antizyme is +1 in mammals, predominantly +1 in fission yeast, but -2 in budding yeast

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12 December 2020

Proteasomal degradation of Smad1 induced by bone morphogenetic proteins

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12 December 2020

Antizyme 3 inhibits polyamine uptake and ornithine decarboxylase (ODC) activity, but does not stimulate ODC degradation

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12 December 2020

[Exogenous antizyme 1 gene transfection inhibits proliferation and promotes apoptosis of human neuroblastoma SH-SY5Y cells in vitro]

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12 December 2020

The N terminus of antizyme promotes degradation of heterologous proteins

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12 December 2020

Cloning and characterization of a rat gene encoding ornithine decarboxylase antizyme

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12 December 2020

Polyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting

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12 December 2020

Nuclear translocation of antizyme and expression of ornithine decarboxylase and antizyme are developmentally regulated

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12 December 2020

1,4-Diaminobutane (putrescine), spermidine, and spermine

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12 December 2020

Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1

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12 December 2020

Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme

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12 December 2020

Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism.

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12 December 2020

Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides growth advantage through neutralization of antizyme functions

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12 December 2020

Expression of a novel human ornithine decarboxylase-like protein in the central nervous system and testes

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12 December 2020

Antizyme1 mediates AURKAIP1-dependent degradation of Aurora-A.

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12 December 2020

Polyamines as targets for therapeutic intervention

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12 December 2020

Stable siRNA-mediated silencing of antizyme inhibitor: regulation of ornithine decarboxylase activity

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12 December 2020

Intracellular localization of ornithine decarboxylase and its regulatory protein, antizyme-1.

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12 December 2020

Increased ornithine decarboxylase activity in murine sarcoma virus infected cells

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12 December 2020

The antizyme family: polyamines and beyond

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12 December 2020

Rapid exchange of subunits of mammalian ornithine decarboxylase

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12 December 2020

Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit

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12 December 2020

Polyamines are essential for cell transformation by pp60v-src: delineation of molecular events relevant for the transformed phenotype

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12 December 2020

Properties of a polyamine transporter regulated by antizyme

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12 December 2020

Cloning of antizyme inhibitor, a highly homologous protein to ornithine decarboxylase

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12 December 2020

Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth

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12 December 2020

Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients

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12 December 2020

Polyamine-dependent gene expression

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12 December 2020

Ornithine decarboxylase induction during B1 progression of normal and Rous sarcoma virus-transformed cells

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12 December 2020

Polyamine metabolism in normal and in virus-transformed chick embryo fibroblasts

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12 December 2020

Identification of nuclear export signals in antizyme-1.

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12 December 2020

Antizyme, a natural ornithine decarboxylase inhibitor, induces apoptosis of haematopoietic cells through mitochondrial membrane depolarization and caspases' cascade.

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12 December 2020

Regulation of all members of the antizyme family by antizyme inhibitor

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12 December 2020

Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding

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12 December 2020

Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity

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12 December 2020

The cellular response to induction of the p21 c-Ha-ras oncoprotein includes stimulation of jun gene expression

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12 December 2020

An ‘integrated model’ of programmed ribosomal frameshifting

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12 December 2020

Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis.

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12 December 2020

Polyamines and cancer: old molecules, new understanding

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12 December 2020

Polyamine sensing during antizyme mRNA programmed frameshifting

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12 December 2020

Trypanosome ornithine decarboxylase is stable because it lacks sequences found in the carboxyl terminus of the mouse enzyme which target the latter for intracellular degradation.

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12 December 2020

Prion: disease or relief?

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12 December 2020

Epigenetic control of polyamines by the prion [PSI+]

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12 December 2020

Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase

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12 December 2020

10.1007/S00018-009-0033-3

Identifiers

DOI

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20 August 2017

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