(Q37465071)

20 August 2017

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title

The beta-thymosins: intracellular and extracellular activities of a versatile actin binding protein family (English)

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20 August 2017

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Hans Georg Mannherz

1

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PubMed ID

19405116

20 August 2017

Ewald Hannappel

series ordinal

2

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20 August 2017

1 October 2009

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20 August 2017

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20 August 2017

66

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20 August 2017

10

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20 August 2017

839-851

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Mapping the binding site of thymosin beta4 on actin by competition with G-actin binding proteins indicates negative co-operativity between binding sites located on opposite subdomains of actin

20 August 2017

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Role of thymosin beta4 in tumor metastasis and angiogenesis

21 January 2018

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The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells

21 January 2018

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Thymosin-beta4 regulates motility and metastasis of malignant mouse fibrosarcoma cells

21 January 2018

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The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins.

21 January 2018

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7 January 2021

Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin.

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7 January 2021

Widely distributed residues in thymosin beta4 are critical for actin binding

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7 January 2021

Identification and quantification of thymosin beta4 in human saliva and tears

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7 January 2021

Induction of the polymerization of actin from the actin:thymosin beta 4 complex by phalloidin, skeletal myosin subfragment 1, chicken intestinal myosin I and free ends of filamentous actin.

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7 January 2021

Plant profilin induces actin polymerization from actin : beta-thymosin complexes and competes directly with beta-thymosins and with negative co-operativity with DNase I for binding to actin

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7 January 2021

Polymerisation of chemically cross-linked actin:thymosin beta(4) complex to filamentous actin: alteration in helical parameters and visualisation of thymosin beta(4) binding on F-actin

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7 January 2021

Thymosin beta 15: a novel regulator of tumor cell motility upregulated in metastatic prostate cancer

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7 January 2021

Ku80 as a novel receptor for thymosin beta4 that mediates its intracellular activity different from G-actin sequestering.

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7 January 2021

Profilin, a multi-modal regulator of neuronal plasticity

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7 January 2021

Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair

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7 January 2021

Ciboulot regulates actin assembly during Drosophila brain metamorphosis

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7 January 2021

Determination of thymosin beta4 and protein in human wound fluid after abdominal surgery

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7 January 2021

Thymosin beta 4 expression and nuclear transport are regulated by hMLH1

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7 January 2021

Actin assembly in response to extracellular signals: role of capping proteins, thymosin beta 4 and profilin

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7 January 2021

Modulation of the interaction between G-actin and thymosin beta 4 by the ATP/ADP ratio: possible implication in the regulation of actin dynamics

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7 January 2021

Tbeta 4 is not a simple G-actin sequestering protein and interacts with F-actin at high concentration

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7 January 2021

Thymosin beta 4 sequesters the majority of G-actin in resting human polymorphonuclear leukocytes

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7 January 2021

Thymosin beta-15 predicts for distant failure in patients with clinically localized prostate cancer-results from a pilot study

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7 January 2021

Probing the phosphoinositide 4,5-bisphosphate binding site of human profilin I

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7 January 2021

The many faces of actin: matching assembly factors with cellular structures

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7 January 2021

Adenosine: trigger and mediator of cardioprotection

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7 January 2021

How is actin polymerization nucleated in vivo?

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7 January 2021

The beta-thymosin/WH2 fold: multifunctionality and structure

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7 January 2021

Rho GTPases in cell biology

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7 January 2021

Proteomic studies of the intrinsically unstructured mammalian proteome.

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7 January 2021

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

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7 January 2021

Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues

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7 January 2021

Co-ordinate regulation of the cytoskeleton in 3T3 cells overexpressing thymosin-beta4.

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7 January 2021

Differential expression of thymosin genes in human tumors and in the developing human kidney

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7 January 2021

Determination of thymosin beta 4 in human blood cells and serum

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7 January 2021

The thymosins. Prothymosin alpha, parathymosin, and beta-thymosins: structure and function

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7 January 2021

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

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7 January 2021

The beta-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly

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7 January 2021

beta-Thymosins, small acidic peptides with multiple functions

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7 January 2021

Thymosin beta4 is released from human blood platelets and attached by factor XIIIa (transglutaminase) to fibrin and collagen

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7 January 2021

Nuclear localisation of the G-actin sequestering peptide thymosin beta4.

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7 January 2021

Thymosin beta4 is not always the main beta-thymosin in mammalian platelets

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7 January 2021

HPLC-ESI-MS analysis of oral human fluids reveals that gingival crevicular fluid is the main source of oral thymosins β4and β10

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7 January 2021

Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins

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7 January 2021

Atomic structure of the actin:DNase I complex

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7 January 2021

Synergy of silent and hot spot mutations in importin beta reveals a dynamic mechanism for recognition of a nuclear localization signal

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7 January 2021

Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces

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7 January 2021

Arp2/3 complex interactions and actin network turnover in lamellipodia.

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7 January 2021

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

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7 January 2021

Evidence that the phosphatidylinositol cycle is linked to cell motility

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7 January 2021

Structure of gelsolin segment 1-actin complex and the mechanism of filament severing

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7 January 2021

Factor XIIIa incorporates thymosin beta4 preferentially into the fibrin(ogen) alphaC-domains.

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7 January 2021

Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.

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7 January 2021

Acanthamoeba profilin interacts with G-actin to increase the rate of exchange of actin-bound adenosine 5'-triphosphate

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7 January 2021

Immunochemical studies on thymosin: radioimmunoassay of thymosin beta 4

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7 January 2021

Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP.

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7 January 2021

How profilin promotes actin filament assembly in the presence of thymosin beta 4.

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7 January 2021

Increased plasma concentrations of cytoskeletal and Ca2+-binding proteins and their peptides in psoriasis patients

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7 January 2021

The rate constant for ATP hydrolysis by polymerized actin.

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7 January 2021

Actin and actin-binding proteins. A critical evaluation of mechanisms and functions

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7 January 2021

Cellular motility driven by assembly and disassembly of actin filaments

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7 January 2021

Drosophila Spire is an actin nucleation factor

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7 January 2021

Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis

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7 January 2021

Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning

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7 January 2021

Isolation of a 5-kilodalton actin-sequestering peptide from human blood platelets

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7 January 2021

Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends

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7 January 2021

Increasing intracellular concentrations of thymosin beta 4 in PtK2 cells: effects on stress fibers, cytokinesis, and cell spreading

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7 January 2021

The structure of crystalline profilin-beta-actin

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7 January 2021

Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury.

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7 January 2021

Thymosin beta4 inhibits benzalkonium chloride-mediated apoptosis in corneal and conjunctival epithelial cells in vitro

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7 January 2021

Thymosin beta 4 suppression of corneal NFkappaB: a potential anti-inflammatory pathway

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7 January 2021

Mechanism of coupled folding and binding of an intrinsically disordered protein

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7 January 2021

The beta-thymosin enigma

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7 January 2021

Actin polymerization induced by GTP gamma S in permeabilized neutrophils is induced and maintained by free barbed ends.

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7 January 2021

Actin binding proteins that change extent and rate of actin monomer-polymer distribution by different mechanisms

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7 January 2021

Interaction of thymosin beta 4 with muscle and platelet actin: implications for actin sequestration in resting platelets

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7 January 2021

Head to tail polymerization of actin

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7 January 2021

The role of profilin complexes in cell motility and other cellular processes

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7 January 2021

In vitro synthesis of thymosin beta 4 encoded by rat spleen mRNA

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7 January 2021

Cloning and sequence analysis of cDNA for rat spleen thymosin beta 4

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7 January 2021

Formation and implications of a ternary complex of profilin, thymosin beta 4, and actin

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7 January 2021

Effects of thymosin beta 4 and thymosin beta 10 on actin structures in living cells

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7 January 2021

Solution conformation of thymosin beta 4: a nuclear magnetic resonance and simulated annealing study

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7 January 2021

Identifiers

DOI

10.1002/CM.20371

1 reference

release_fo7glqe6ujcxli7mxvlpvszz7m

20 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fo7glqe6ujcxli7mxvlpvszz7m

24 November 2022

mapped directly with Wikidata item

PubMed ID

19405116

1 reference

PubMed ID

19405116