(Q37467580)

English

Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation

scientific article published on December 2009

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Statements

scholarly article

1 reference

Europe PubMed Central

20 August 2017

Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation (English)

1 reference

Europe PubMed Central

20 August 2017

phosphorylation

0 references

1 reference

based on heuristic

inferred from title

author name string

Jeong-Ho Kim

1

1 reference

Europe PubMed Central

20 August 2017

Mee-Sup Yoon

2

1 reference

Europe PubMed Central

20 August 2017

Jie Chen

3

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

1 December 2009

1 reference

Europe PubMed Central

20 August 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

20 August 2017

284

1 reference

Europe PubMed Central

20 August 2017

51

1 reference

Europe PubMed Central

20 August 2017

35425-35432

1 reference

Europe PubMed Central

20 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2790971/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

1 reference

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23 August 2017

Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation

1 reference

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23 August 2017

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

1 reference

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Role of dietary proteins and amino acids in the pathogenesis of insulin resistance

1 reference

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Attenuation of leptin and insulin signaling by SOCS proteins

1 reference

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Notch signalling regulates stem cell numbers in vitro and in vivo

1 reference

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1 reference

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Growing roles for the mTOR pathway

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Upstream and downstream of mTOR

1 reference

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Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

1 reference

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STAT proteins: From normal control of cellular events to tumorigenesis

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BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells

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A new role for SOCS in insulin action. Suppressor of cytokine signaling

1 reference

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Splanchnic glucose and amino acid metabolism in obesity

1 reference

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SOCS: physiological suppressors of cytokine signaling

1 reference

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23 August 2017

Serine phosphorylation of STATs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790971

23 August 2017

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

1 reference

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

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Bidirectional modulation of insulin action by amino acids

1 reference

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23 August 2017

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

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23 August 2017

Interleukin-6 depletion selectively improves hepatic insulin action in obesity

1 reference

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23 August 2017

Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin

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6 September 2017

Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway

1 reference

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14 September 2017

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

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Interleukin-6 induces cellular insulin resistance in hepatocytes

1 reference

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Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells

1 reference

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Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation.

1 reference

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STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta.

1 reference

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The dual function of hepatic SOCS3 in insulin resistance in vivo.

1 reference

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Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.

1 reference

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Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.

1 reference

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Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.

1 reference

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Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo

1 reference

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Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

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Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival

1 reference

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Mechanism of amino acid-induced skeletal muscle insulin resistance in humans

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Effect of long-term dietary protein intake on glucose metabolism in humans.

1 reference

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The disease burden associated with overweight and obesity

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Plasma Amino Acid Levels and Insulin Secretion in Obesity

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FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

1 reference

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Influence of dietary deprivations on plasma concentration of free amino acids of man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19875458

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inferred from PubMed ID database lookup

Are Plasma Amino Acid Levels Elevated in Obesity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19875458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19875458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.051516

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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