(Q37468546)

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Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications.

scientific article published on March 2006

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27 January 2020

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Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications (English)

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27 January 2020

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based on heuristic

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hepatic encephalopathy

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1

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27 January 2020

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27 January 2020

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27 January 2020

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Pilar Monfort

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27 January 2020

Slaven Erceg

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1 March 2006

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27 January 2020

Neuropsychiatric Disease and Treatment

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27 January 2020

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27 January 2020

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27 January 2020

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27 January 2020

Characteristics of minimal hepatic encephalopathy

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23 August 2017

Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells

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23 August 2017

Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998.

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23 August 2017

Quality of life in cirrhotics with minimal hepatic encephalopathy

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Factors associated with poor health-related quality of life of patients with cirrhosis

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Genetic analysis of learning behavior-induced structural plasticity

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Formation of temporal memory requires NMDA receptors within CA1 pyramidal neurons

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Genetic enhancement of learning and memory in mice

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23 August 2017

The type and the localization of cAMP-dependent protein kinase regulate transmission of cAMP signals to the nucleus in cortical and cerebellar granule cells

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Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice

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The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

1 reference

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23 August 2017

PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice

1 reference

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Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

1 reference

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23 August 2017

Nonalcoholic cirrhosis associated with neuropsychological dysfunction in the absence of overt evidence of hepatic encephalopathy.

1 reference

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23 August 2017

Excitatory amino acid antagonists and memory: effect of drugs acting at N-methyl-D-aspartate receptors in learning and memory tasks

1 reference

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23 August 2017

Quantitative EEG analysis and evoked potentials to measure (latent) hepatic encephalopathy

1 reference

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23 August 2017

Cognitive deficits associated with chronic hepatic encephalopathy and their response to levodopa

1 reference

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23 August 2017

Spectral versus visual EEG analysis in mild hepatic encephalopathy

1 reference

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6 September 2017

Altered adaptive behaviour expressed in an open-field paradigm in experimental hepatic encephalopathy.

1 reference

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26 June 2018

Chronic hyperammonemia impairs the glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Diurnal and gender effects by chronic portacaval shunting in rats on spontaneous locomotor and rearing activities in an open-field

1 reference

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26 June 2018

Stenosis of a portacaval anastomosis affects circadian locomotor activity in the rat: a multivariable analysis

1 reference

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26 June 2018

Inhibitory learning and memory in newborn rats

1 reference

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26 June 2018

Further evidence for the involvement of a hippocampal cGMP/cGMP-dependent protein kinase cascade in memory consolidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Posttraining injections of MK-801 produce a time-dependent impairment of memory in two water maze tasks.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Diagnostic tools for the detection of subclinical hepatic encephalopathy: comparison of standard and computerized psychometric tests with spectral-EEG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

A low-protein diet ameliorates disrupted diurnal locomotor activity in rats after portacaval anastomosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Allocentric spatial learning by hippocampectomised rats: a further test of the "spatial mapping" and "working memory" theories of hippocampal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Behavioral effects of experimental portacaval anastomosis measured in Dashiell and radial tunnel maze configurations.

1 reference

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26 June 2018

Memory impairments concomitant with nonalcoholic cirrhosis.

1 reference

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26 June 2018

Brain 5-HT1 and 5-HT2 binding sites following portacaval shunt in the rat.

1 reference

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26 June 2018

A simple animal model of hyperammonemia

1 reference

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26 June 2018

Portacaval shunt in the rat: selective alterations in behavior and brain serotonin

1 reference

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26 June 2018

Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy.

1 reference

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26 June 2018

Portacaval anastomosis disrupts circadian locomotor activity and pineal melatonin rhythms in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

26 June 2018

Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671733

2 September 2018

Evaluation of two experimental models of hepatic encephalopathy in rats

1 reference

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2 September 2018

Bile duct ligation plus hyperammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patients

1 reference

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2 September 2018

Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts

1 reference

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2 September 2018

Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites.

1 reference

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2 September 2018

Lack of detrimental effects of nitric oxide inhibition in bile duct-ligated rats with hepatic encephalopathy

1 reference

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2 September 2018

Memory function in early hepatic encephalopathy.

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2 September 2018

Ammonia levels and the severity of hepatic encephalopathy.

1 reference

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2 September 2018

Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients.

1 reference

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2 September 2018

Neuronal nitric oxide has a role as a perfusion regulator and a synaptic modulator in cerebellum but not in neocortex during somatosensory stimulation--an animal PET study.

1 reference

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2 September 2018

Sildenafil (viagra) is a risk factor for acute variceal bleeding

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2 September 2018

Effect of repeated L-histidine administration on plasma prolactin and growth hormone levels in rats.

1 reference

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2 September 2018

cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation

1 reference

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2 September 2018

Attention deficits in minimal hepatic encephalopathy.

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2 September 2018

Subclinical hepatic encephalopathy predicts the development of overt hepatic encephalopathy

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2 September 2018

Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patients

1 reference

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2 September 2018

Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis

1 reference

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2 September 2018

Modulation of learning processes by ionotropic glutamate receptor ligands.

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2 September 2018

A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze

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2 September 2018

Effects of the histamine H(1) receptor blocker, pyrilamine, on spontaneous locomotor activity of rats with long-term portacaval anastomosis.

1 reference

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Neuropsychological aspects of portal-systemic encephalopathy

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2 September 2018

The effect of dizocilpine (MK-801) on conditional discrimination learning in the rat.

1 reference

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2 September 2018

Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats.

1 reference

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2 September 2018

Phenserine, a novel acetylcholinesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockade of the N-methyl-D-aspartate receptor.

1 reference

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2 September 2018

Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit T-maze.

1 reference

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2 September 2018

Intracerebroventricular injection of N omega-nitro-L-arginine in rats impairs learning in a 14-unit T-maze.

1 reference

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2 September 2018

Learning in a 14-unit T-maze is impaired in rats following systemic treatment with N omega-nitro-L-arginine.

1 reference

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2 September 2018

High prevalence of sleep disturbance in cirrhosis.

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2 September 2018

Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: effects of 7-nitroindazole and zaprinast.

1 reference

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2 September 2018

Reduction of dizocilpine and scopolamine-induced deficits in avoidance responding by SCH 54388, a metabolite of felbamate.

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2 September 2018

NMDA receptor antagonist MK-801 selectively impairs learning of the contiguity of the conditioned stimulus and unconditioned stimulus in goldfish.

1 reference

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2 September 2018

Memory-related changes of nitric oxide synthase activity and nitrite level in rat brain.

1 reference

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2 September 2018

Neuropsychological characterization and detection of subclinical hepatic encephalopathy.

1 reference

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2 September 2018

Effects of combined block of alpha 1-adrenoceptors and NMDA receptors on spatial and passive avoidance behavior in rats.

1 reference

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2 September 2018

Disruption of the diurnal rhythm of plasma melatonin in cirrhosis.

1 reference

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2 September 2018

Latent portasystemic encephalopathy. I. Nature of cerebral functional defects and their effect on fitness to drive.

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2 September 2018

Changes in Glutamate Receptors on Synaptic Membranes Associated with Hepatic Encephalopathy or Hyperammonemia in the Rabbit

1 reference

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2 September 2018

Clinical features and survivial of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric tests

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclinical hepatic encephalopathy impairs daily functioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver cirrhosis and circadian rhythm

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic significance of subclinical hepatic encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fitness to drive in patients with cirrhosis and portal-systemic shunting: a pilot study evaluating driving performance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome Oxidase Activity of the Suprachiasmatic Nucleus and Pineal Gland in Rats with Portacaval Shunt

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic hepatic encephalopathy. A psychometrical study

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https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclinical hepatic encephalopathy: detection, prevalence, and relationship to nitrogen metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melatonin serum levels and metabolic clearance rate in patients with liver cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The electroencephalograph in liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Release and Neosynthesis of Glutamic Acid Are Increased in Experimental Models of Hepatic Encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychomotor performance defects in cirrhotic patients without overt encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19412446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19412446%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19412446%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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