(Q37474767)

English

Selective abstraction of 2H from C-5' of thymidylate in an oligodeoxynucleotide by the radical center at C-6 of the diradical species of neocarzinostatin: chemical evidence for the structure of the activated drug-DNA complex

scientific article published on April 15, 1991

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Selective abstraction of 2H from C-5' of thymidylate in an oligodeoxynucleotide by the radical center at C-6 of the diradical species of neocarzinostatin: chemical evidence for the structure of the activated drug-DNA complex (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

S. M. Meschwitz

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826561

3 December 2022

I. H. Goldberg

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826561

3 December 2022

language of work or name

0 references

publication date

1 April 1991

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

15 April 1991

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1826561

3 December 2022

full work available at URL

https://europepmc.org/articles/PMC51381

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826561

3 December 2022

https://europepmc.org/articles/PMC51381?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826561

3 December 2022

https://pnas.org/doi/pdf/10.1073/pnas.88.8.3047

1 reference

10.1073/PNAS.88.8.3047

https://api.crossref.org/works/10.1073/PNAS.88.8.3047

3 December 2022

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

88

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

3047-3051

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Polymer support oligonucleotide synthesis XVIII: use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

23 August 2017

57 Sequencing end-labeled DNA with base-specific chemical cleavages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

23 August 2017

Activation of neocarzinostatin chromophore and formation of nascent DNA damage do not require molecular oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

23 August 2017

Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

23 August 2017

Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at cytosine residues in DNA: evidence for a possible role in mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

23 August 2017

Molecular models of neocarzinostatin damage of DNA: analysis of sequence dependence in 5'GAGCG:5'CGCTC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

23 August 2017

Neocarzinostatin: Spectral characterization and separation of a non-protein chromophore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

6 September 2017

Free radical mechanisms in neocarzinostatin-induced DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

6 September 2017

Duplex-hairpin transitions in DNA: NMR studies on CGCGTATACGCG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

14 September 2017

Neocarzinostatin chromophore. Assignment of spectral properties and structural requirements for binding to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

26 June 2018

Neocarzinostatin-induced DNA base release accompanied by staggered oxidative cleavage of the complementary strand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

26 June 2018

Neocarzinostatin-induced hydrogen atom abstraction from C-4' and C-5' of the T residue at a d(GT) step in oligonucleotides: shuttling between deoxyribose attack sites based on isotope selection effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

26 June 2018

Strand-scission of DNA by neocarzinostatin, auromomycin, and bleomycin: studies on base release and nucleotide sequence specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

2 September 2018

Atypical abasic sites generated by neocarzinostatin at sequence-specific cytidylate residues in oligodeoxynucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51381

2 September 2018

Mode of reversible binding of neocarzinostatin chromophore to DNA: evidence for binding via the minor groove

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of 2-deoxyribonolactone at the site of neocarzinostatin-induced cytosine release in the sequence d(AGC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence-specific double-strand breakage of DNA by neocarzinostatin involves different chemical mechanisms within a staggered cleavage site

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neocarzinostatin chromophore: Presence of a highly strained ether ring and its reaction with mercaptan and sodium borohydride

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5' of deoxyribose

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of the nonprotein chromophore of neocarzinostatin to deoxyribonucleic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neocarzinostatin chromophore binds to deoxyribonucleic acid by intercalation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sites in the diyne-ene bicyclic core of neocarzinostatin chromophore responsible for hydrogen abstraction from DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of activation of the antitumor antibiotic neocarzinostatin by mercaptan and sodium borohydride

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.88.8.3047

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1991PNAS...88.3047M

0 references

release_cbakthqz2rhz3jywix6iuzdth4

1 reference

https://api.fatcat.wiki/v0/release/cbakthqz2rhz3jywix6iuzdth4

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

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