(Q37474894)

20 August 2017

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title

Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters (English)

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20 August 2017

2

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20 August 2017

Tadashi Yokosuka

1

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20 August 2017

publication date

1 May 2009

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20 August 2017

published in

Immunological Reviews

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20 August 2017

volume

229

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20 August 2017

issue

1

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20 August 2017

page(s)

27-40

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Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells

20 August 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

CD28 signals in the immature immunological synapse

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

CD28 and lipid rafts coordinate recruitment of Lck to the immunological synapse of human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Filamin A is required for T cell activation mediated by protein kinase C-theta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Immunological synapse formation licenses CD40-CD40L accumulations at T-APC contact sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Relevance of CD6-mediated interactions in T cell activation and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Supported planar membranes in studies of cell-cell recognition in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the g

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Vav-1 and the IKK alpha subunit of I kappa B kinase functionally associate to induce NF-kappa B activation in response to CD28 engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

Engagement of CD28 outside of the immunological synapse results in up-regulation of IL-2 mRNA stability but not IL-2 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2009.00779.X

10.1111/J.1600-065X.2009.00779.X

21 January 2018

Identifiers

DOI

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20 August 2017

1 reference