(Q37474990)

20 August 2017

Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1. (English)

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20 August 2017

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Guofei Zhou

1

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20 August 2017

Laura A Dada

2

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20 August 2017

Minghua Wu

3

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20 August 2017

Aileen Kelly

4

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20 August 2017

Humberto Trejo

5

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20 August 2017

Qiyuan Zhou

6

1 reference

20 August 2017

John Varga

7

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20 August 2017

Jacob I Sznajder

8

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20 August 2017

2 October 2009

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American Journal of Physiology - Lung Cellular and Molecular Physiology

20 August 2017

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20 August 2017

297

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20 August 2017

6

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20 August 2017

L1120-30

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describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2793183/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Notch signaling mediates hypoxia-induced tumor cell migration and invasion

23 August 2017

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23 August 2017

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Direct regulation of TWIST by HIF-1alpha promotes metastasis

23 August 2017

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A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

23 August 2017

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Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

23 August 2017

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23 August 2017

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23 August 2017

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

23 August 2017

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Hypoxia induces transforming growth factor-beta1 gene expression in the pulmonary artery of rats via hypoxia-inducible factor-1alpha

23 August 2017

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Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse

23 August 2017

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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

23 August 2017

1 reference

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RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

23 August 2017

1 reference

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Complex networks orchestrate epithelial-mesenchymal transitions

23 August 2017

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Multiple roles of alpha-smooth muscle actin in mechanotransduction

23 August 2017

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Reactive oxygen species production via NADPH oxidase mediates TGF-beta-induced cytoskeletal alterations in endothelial cells

23 August 2017

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23 August 2017

1 reference

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Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung

23 August 2017

1 reference

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

23 August 2017

1 reference

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TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

23 August 2017

1 reference

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Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis

23 August 2017

1 reference

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HIF-1 and hypoxic response: the plot thickens.

23 August 2017

1 reference

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The role of epithelial-to-mesenchymal transition in renal fibrosis

23 August 2017

1 reference

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Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury

23 August 2017

1 reference

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Targeting HIF-1 for cancer therapy

23 August 2017

1 reference

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

23 August 2017

1 reference

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Transcription. Oxygen sensing gets a second wind

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

23 August 2017

1 reference

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

23 August 2017

1 reference

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Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)

23 August 2017

1 reference

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Cells depleted of mitochondrial DNA (rho0) yield insight into physiological mechanisms

23 August 2017

1 reference

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

23 August 2017

1 reference

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Redox-mediated activation of latent transforming growth factor-beta 1

23 August 2017

1 reference

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Renewal of alveolar epithelium in the rat following exposure to NO2

23 August 2017

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Pulmonary alveolar epithelial cell differentiation

23 August 2017

1 reference

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Hypoxia-inducible factor-1 transactivates transforming growth factor-beta3 in trophoblast

23 August 2017

1 reference

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Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

6 September 2017

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Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function.

6 September 2017

1 reference

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Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

TGF beta1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lu cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Asbestos-derived reactive oxygen species activate TGF-beta1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Type II alveolar cell. Defender of the alveolus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Alveolar type 1 cells express the alpha2 Na,K-ATPase, which contributes to lung liquid clearance

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Differential effects of TGF-beta1 and BMP-4 on the hypoxic induction of cyclooxygenase-2 in human pulmonary artery smooth muscle cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793183

Impaired homeostasis and phenotypic abnormalities in Prdx6-/-mice lens epithelial cells by reactive oxygen species: increased expression and activation of TGFbeta

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19801454

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparative expression profiling in pulmonary fibrosis suggests a role of hypoxia-inducible factor-1alpha in disease pathogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19801454

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPLUNG.00007.2009

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

19801454

1 reference