(Q37479222)

English

Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.

scientific article published on 28 October 2009

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864413%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864413%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Alzheimer's disease

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13

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11 February 2020

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Saori Hata

1

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11 February 2020

Sayaka Fujishige

2

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11 February 2020

Yoichi Araki

3

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11 February 2020

Naoko Kato

4

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11 February 2020

Masahiko Araseki

5

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11 February 2020

Masaki Nishimura

6

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11 February 2020

Dieter Hartmann

7

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11 February 2020

Paul Saftig

8

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11 February 2020

Falk Fahrenholz

9

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11 February 2020

Miyako Taniguchi

10

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11 February 2020

Katsuya Urakami

11

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11 February 2020

Hiroyasu Akatsu

12

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11 February 2020

Kazuo Yamamoto

14

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11 February 2020

Masahiro Maeda

15

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11 February 2020

Tohru Yamamoto

16

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11 February 2020

Tadashi Nakaya

17

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11 February 2020

Sam Gandy

18

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11 February 2020

Toshiharu Suzuki

19

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11 February 2020

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28 October 2009

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11 February 2020

Journal of Biological Chemistry

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11 February 2020

284

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11 February 2020

52

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11 February 2020

36024-36033

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11 February 2020

Regulation of the physiological function and metabolism of AbetaPP by AbetaPP binding proteins

1 reference

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23 August 2017

A conserved function of C. elegans CASY-1 calsyntenin in associative learning

1 reference

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23 August 2017

Calsyntenins mediate TGN exit of APP in a kinesin-1-dependent manner.

1 reference

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23 August 2017

Regulation of amyloid beta-protein precursor by phosphorylation and protein interactions

1 reference

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23 August 2017

CASY-1, an ortholog of calsyntenins/alcadeins, is essential for learning in Caenorhabditis elegans

1 reference

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23 August 2017

The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport

1 reference

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23 August 2017

Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis

1 reference

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23 August 2017

The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease

1 reference

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23 August 2017

Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation

1 reference

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23 August 2017

ADAMs family members as amyloid precursor protein alpha-secretases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794718

23 August 2017

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism

1 reference

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23 August 2017

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

1 reference

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23 August 2017

Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production

1 reference

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23 August 2017

Alzheimer's disease: genes, proteins, and therapy

1 reference

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23 August 2017

Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain

1 reference

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23 August 2017

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

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23 August 2017

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

1 reference

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23 August 2017

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

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23 August 2017

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

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23 August 2017

Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases

1 reference

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14 September 2017

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

1 reference

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14 September 2017

X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain

1 reference

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26 June 2018

Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan.

1 reference

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26 June 2018

Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype.

1 reference

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26 June 2018

Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation

1 reference

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2 September 2018

Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease.

1 reference

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Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain.

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2 September 2018

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

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Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS.

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Novel presenilin 1 mutations associated with early onset of dementia in a family with both early-onset and late-onset Alzheimer disease

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10.1074/JBC.M109.057497

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11 February 2020

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11 February 2020

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11 February 2020

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