(Q37481315)

English

The alpha 1B/D-adrenoceptor knockout mouse permits isolation of the vascular alpha 1A-adrenoceptor and elucidates its relationship to the other subtypes.

scientific article published on 30 June 2009

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scholarly article

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1 February 2020

The alpha 1B/D-adrenoceptor knockout mouse permits isolation of the vascular alpha 1A-adrenoceptor and elucidates its relationship to the other subtypes (English)

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1 February 2020

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John C. McGrath

4

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1 February 2020

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L Methven

1

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1 February 2020

M McBride

2

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1 February 2020

G A Wallace

3

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1 February 2020

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30 June 2009

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1 February 2020

British Journal of Pharmacology

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1 February 2020

158

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1 February 2020

1

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1 February 2020

209-224

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1 February 2020

Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Evidence for involvement of alpha1D-adrenoceptors in contraction of femoral resistance arteries using knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

3-d image analysis of fluorescent drug binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

New aspects of vascular remodelling: the involvement of all vascular cell types.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Fluorescent ligands, antibodies, and proteins for the study of receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Alpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-AR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Knockout of the alpha 1A/C-adrenergic receptor subtype: the alpha 1A/C is expressed in resistance arteries and is required to maintain arterial blood pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Vascular adrenoceptors: an update.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Expression of multiple alpha1-adrenoceptors on vascular smooth muscle: correlation with the regulation of contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Vascular alpha 1D-adrenoceptors have a role in the pressor response to phenylephrine in the pithed rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

23 August 2017

Subtype-specific dimerization of alpha 1-adrenoceptors: effects on receptor expression and pharmacological properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

14 September 2017

International Union of Pharmacology. X. Recommendation for nomenclature of alpha 1-adrenoceptors: consensus update.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

14 September 2017

Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Cellular trafficking of human alpha1a-adrenergic receptors is continuous and primarily agonist-independent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Hepatocytes from alpha1B-adrenoceptor knockout mice reveal compensatory adrenoceptor subtype substitution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Alpha1-adrenoceptor subtypes involved in vasoconstrictor responses to exogenous and neurally released noradrenaline in rat femoral resistance arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Regulation of the cellular localization and signaling properties of the alpha(1B)- and alpha(1D)-adrenoceptors by agonists and inverse agonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

alpha 1D-adrenoceptors contribute to the neurogenic vasopressor response in pithed rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): role of the alpha-1L adrenoceptor in tissue selectivity, part II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): role of the alpha-1L adrenoceptor in tissue selectivity, part I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Characterization of an α1D‐adrenoceptor mediating the contractile response of rat aorta to noradrenaline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

26 June 2018

Beta-arrestin-dependent spontaneous alpha1a-adrenoceptor endocytosis causes intracellular transportation of alpha-blockers via recycling compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

The N terminus of the human alpha1D-adrenergic receptor prevents cell surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

Role of the alpha1D-adrenergic receptor in the development of salt-induced hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

A knockout approach indicates a minor vasoconstrictor role for vascular alpha1B-adrenoceptors in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

Hypothesis for the initiation of vasomotion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

Single-cell recombinant pharmacology: bovine alpha(1a)-adrenoceptors in rat-1 fibroblasts release intracellular ca(2+), display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795267

2 September 2018

5-Methyl-urapidil discriminates between subtypes of the alpha 1-adrenoceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

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Characterization of alpha-1 adrenoceptor subtypes in human and canine prostate membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human liver alpha 1-adrenoceptors: predominance of the alpha 1A subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1-adrenoceptor-induced contractility in rat aorta is mediated by the alpha 1D subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1-adrenoceptors mediating contraction in arteries of normotensive and spontaneously hypertensive rats are of the alpha 1D or alpha 1A subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and in vitro characterization of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective alpha 1A receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subtype-specific differences in subcellular localization of alpha1-adrenoceptors: chlorethylclonidine preferentially alkylates the accessible cell surface alpha1-adrenoceptors irrespective of the subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical localization of the alpha-1B adrenergic receptor and the contribution of this and the other subtypes to vascular smooth muscle contraction: analysis with selective ligands and antisense oligonucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential alpha1-adrenoceptor labeling by [3H]prazosin and [3H]tamsulosin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha1A-adrenoceptors predominate in the control of blood pressure in mouse mesenteric vascular bed

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2009.00269.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19572943%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

release_hp4a64c6rvchxacvbjzixgdjry

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https://api.fatcat.wiki/v0/release/hp4a64c6rvchxacvbjzixgdjry

24 November 2022

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19572943%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19572943%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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